scholarly journals Moment reconstruction and moment‐adjusted imputation when exposure is generated by a complex, nonlinear random effects modeling process

Biometrics ◽  
2016 ◽  
Vol 72 (4) ◽  
pp. 1369-1377
Author(s):  
Cornelis J. Potgieter ◽  
Rubin Wei ◽  
Victor Kipnis ◽  
Laurence S. Freedman ◽  
Raymond J. Carroll
Keyword(s):  
Random Effects ◽  
Modeling Process ◽  
Random Effects Modeling

Electrocautery Adenoidectomy Outcomes: A Metaanalysis

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P33-P34
Author(s):  
Jeremy T. Reed ◽  
Shankar K. Sridhara ◽  
Scott E Brietzke
Keyword(s):  
Sample Size ◽  
Random Effects ◽  
English Language ◽  
Operative Time ◽  
Inclusion Criteria ◽  
Subjective Success ◽  
Random Effects Modeling ◽  
Lost To Follow Up

Objective Review and assess the current published literature regarding clinical outcomes of suction electrocautery adenoidectomy (ECA) in pediatric patients. Methods The MEDLINE database was systematically reviewed for articles reporting on the use of ECA. Inclusion criteria included English language, sample size greater than 5, and presentation of extractable data regarding pediatric outcomes with ECA. Random effects modeling was used to estimate summary outcomes. Results 9 studies met the inclusion criteria. There were 2 level 1b studies, 2 level 3b studies, and 5 level 4 studies. The mean sample size was 276 patients with a grand mean age of 6.0 years. Random effects modeling of summary estimates of intra-operative hemorrhage (4.1 cc vs. 24.0 cc 95% CI of difference = 16.5–23.1, p<0.001) and operative time (10.0 minutes vs. 11.9 minutes 95% CI of difference=0.82–2.90, p<0.001) favored ECA vs. traditional curette adenoidectomy. Subjective success was reported in 95.0% (95% CI=92.7–97.3%, p<0.001) of ECA patients with a grand mean of 5.8 months of postoperative follow-up and a grand mean lost to follow-up rate of 23.2%. Adenoid regrowth was evaluated objectively (endoscopy or X-ray) in only 116 of 2,132 (5.4%) total patients with an observed regrowth rate of 2.8% (95% CI=0–5.5%, p=0.052) with 846 total person years of follow-up. Conclusions The preponderance of evidence favors ECA versus curette adenoidectomy in terms of decreased intraoperative hemorrhage and decreased operative time. Long-term outcomes data for ECA are scarce, despite the fact that the procedure is likely performed hundreds of times each day, but suggest a low regrowth rate.

2. Random-Effects Modeling of Categorical Response Data

2000 ◽  
Vol 30 (1) ◽  
pp. 27-80 ◽  
Author(s):  
Alan Agresti ◽  
James G. Booth ◽  
James P. Hobert ◽  
Brian Caffo
Keyword(s):  
Random Effects ◽  
Response Data ◽  
Categorical Response ◽  
Random Effects Modeling

Random-Effects Modeling

2013 ◽  
pp. 1618-1618
Author(s):  
Kristine M. Molina ◽  
Kristine M. Molina ◽  
Heather Honoré Goltz ◽  
Marc A. Kowalkouski ◽  
Stacey L. Hart ◽  
...  
Keyword(s):  
Random Effects ◽  
Random Effects Modeling

Prevalence of Barrett’s esophagus in obese patients undergoing pre-bariatric surgery evaluation: a systematic review and meta-analysis

Endoscopy ◽  
2020 ◽  
Vol 52 (07) ◽  
pp. 537-547 ◽  
Author(s):  
Bashar Qumseya ◽  
Sherif Gendy ◽  
Alexander Wallace ◽  
Dennis Yang ◽  
Davis Estores ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Risk Factor ◽  
Barrett’S Esophagus ◽  
Random Effects ◽  
Barrett's Esophagus ◽  
Positive Association ◽  
Major Risk Factor ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Random Effects Modeling

Abstract Introduction Obesity is a known risk factor for gastroesophageal reflux disease (GERD), Barrett’s esophagus (BE), and esophageal adenocarcinoma (EAC). Obese patients routinely undergo preoperative esophagogastroduodenoscopy (EGD) before bariatric procedures. We aimed to assess the prevalence of BE in this patient population. Methods We conducted a comprehensive literature search ending in March 2019. Search results were imported into covidence.org and screened by two independent reviewers. Heterogeneity was assessed using I 2 and Q statistics and publication bias using funnel plots and the Orwin fail-safe test. Random-effects modeling was used in all analyses. Results Of 4087 citations, 77 were reviewed in full text and 29 were included in the final analysis based on our predetermined inclusion/exclusion criteria. A total of 13 434 patients underwent pre-bariatric surgery EGD. The pooled prevalence of BE using random-effects modeling was 0.9 % (95 % confidence interval [CI] 0.7 % – 1.3 %); P < 0.001; I 2 = 58 %, Q = 67). In meta-regression analyses, controlling for sex and GERD, we found a positive association between mean body mass index (BMI) and the prevalence of BE (β = 0.15 [95 %CI 0.02 – 0.28]; P = 0.03). A linear relationship between the prevalence of BE and the prevalence of GERD was also noted (β = 3.9 [95 %CI 0.4 – 7.5]; P = 0.03). Conclusions Obesity has been postulated as a major risk factor for BE, yet we found that the prevalence of BE in morbidly obese patients undergoing preoperative EGD was very low. Therefore, obesity alone may not be a major risk factor for BE.

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