scholarly journals Chemical signalling in lizards: an interspecific comparison of femoral pore numbers in Lacertidae

2014 ◽  
Vol 114 (1) ◽  
pp. 44-57 ◽  
Author(s):  
Simon Baeckens ◽  
Shelley Edwards ◽  
Katleen Huyghe ◽  
Raoul Van Damme
Marine Drugs ◽  
2021 ◽  
Vol 19 (2) ◽  
pp. 109
Author(s):  
Hani A. Alhadrami ◽  
Bathini Thissera ◽  
Marwa H. A. Hassan ◽  
Fathy A. Behery ◽  
Che Julius Ngwa ◽  
...  

Coculture is a productive technique to trigger microbes’ biosynthetic capacity by mimicking the natural habitats’ features principally by competition for food and space and interspecies cross-talks. Mixed cultivation of two Red Sea-derived actinobacteria, Actinokineospora spheciospongiae strain EG49 and Rhodococcus sp. UR59, resulted in the induction of several non-traced metabolites in their axenic cultures, which were detected using LC–HRMS metabolomics analysis. Antimalarial guided isolation of the cocultured fermentation led to the isolation of the angucyclines actinosporins E (1), H (2), G (3), tetragulol (5) and the anthraquinone capillasterquinone B (6), which were not reported under axenic conditions. Interestingly, actinosporins were previously induced when the axenic culture of the Actinokineospora spheciospongiae strain EG49 was treated with signalling molecule N-acetyl-d-glucosamine (GluNAc); this finding confirmed the effectiveness of coculture in the discovery of microbial metabolites yet to be discovered in the axenic fermentation with the potential that could be comparable to adding chemical signalling molecules in the fermentation flask. The isolated angucycline and anthraquinone compounds exhibited in vitro antimalarial activity and good biding affinity against lysyl-tRNA synthetase (PfKRS1), highlighting their potential developability as new antimalarial structural motif.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Tim Liebisch ◽  
Armin Drusko ◽  
Biena Mathew ◽  
Ernst H. K. Stelzer ◽  
Sabine C. Fischer ◽  
...  

AbstractDuring the mammalian preimplantation phase, cells undergo two subsequent cell fate decisions. During the first decision, the trophectoderm and the inner cell mass are formed. Subsequently, the inner cell mass segregates into the epiblast and the primitive endoderm. Inner cell mass organoids represent an experimental model system, mimicking the second cell fate decision. It has been shown that cells of the same fate tend to cluster stronger than expected for random cell fate decisions. Three major processes are hypothesised to contribute to the cell fate arrangements: (1) chemical signalling; (2) cell sorting; and (3) cell proliferation. In order to quantify the influence of cell proliferation on the observed cell lineage type clustering, we developed an agent-based model accounting for mechanical cell–cell interaction, i.e. adhesion and repulsion, cell division, stochastic cell fate decision and cell fate heredity. The model supports the hypothesis that initial cell fate acquisition is a stochastically driven process, taking place in the early development of inner cell mass organoids. Further, we show that the observed neighbourhood structures can emerge solely due to cell fate heredity during cell division.


PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0132094 ◽  
Author(s):  
Yongjun Zhang ◽  
Qing S. Cao ◽  
Daniel I. Rubenstein ◽  
Sen Zang ◽  
Melissa Songer ◽  
...  

2005 ◽  
Vol 21 (3) ◽  
pp. 317-328 ◽  
Author(s):  
E. V. J. Tanner ◽  
V. K. Teo ◽  
D. A. Coomes ◽  
J. J. Midgley

To investigate whether seedlings of ten dipterocarp species differed significantly in terms of growth and mortality or whether species were not significantly different and could be considered ecologically similar, seedlings were grown, two per pot, in two experiments: (1) where the two seedlings were of equal height (30 cm); and (2) where one seedling was 10 cm shorter than the other. Seedlings were grown in a shade house with 15% above-canopy light in a 50:50 forest soil–sand mixture and were watered frequently; pots were placed so that seedling density was 130 seedlings m−2 of ground. In the first experiment there were 45 pairwise combinations of species when seedlings were 30 cm tall (AB, AC, AD,…. BC, BD…IJ; where A, B, C…J signify different species); each combination was replicated 10 times so there were 450 pots with 900 seedlings. In the second experiment there were 100 pairwise combinations of species and size e.g. Aa (30 cm A with 20 cm a), Ab (30 cm A with 20 cm b), each combination was replicated 10 times hence there were 1000 pots with 2000 seedlings. After 22 mo 79% of the initial 2900 seedlings survived; on average they had grown 42 cm (i.e. to 72 cm tall from their initial 30 cm). The most frequent outcome of competition-trials between different sized individuals (784 of 1000 trials) was that the initially taller seedling of each pair ‘won’ (it was the taller or surviving seedling). When 900 of these trials (setting aside, Aa, Bb, Cc etc.) were analysed as 45 comparisons between species with different sized individuals (Ab and aB are one interspecific comparison for these purposes), initial height determined the outcome in 23 cases (even in some competitions between light hardwood species and heavy hardwood species); in 6 cases a species (mostly light hardwoods) behaved as a ‘dominant’ – they usually won even if they were smaller initially. We found few significant differences between species in: initial seedling heights; leaf nitrogen concentrations; and specific leaf areas when they were grown in similar conditions, and these attributes were not correlated with growth rates. The similarity of seedlings of different species meant that often a height difference of just 10 cm was enough to determine the outcome of a pairwise competition-trial in high seedling densities and light equivalent to that in forest gaps.


2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Anbalagan Rathinakumar ◽  
Murugavel Baheerathan ◽  
Barbara A. Caspers ◽  
Joseph J. Erinjery ◽  
Perumalswamy Kaliraj ◽  
...  

2019 ◽  
pp. 163-176
Author(s):  
Melanie Clapham ◽  
Owen T. Nevin ◽  
Ian Convery

Author(s):  
ERIC S. ALBONE ◽  
PAULINE E. GOSDEN ◽  
GEORGES C. WARE ◽  
DAVID W. MACDONALD ◽  
NICHOLAS G. HOUGH

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