Treatment Resistance in Bipolar Affective Disorder with Recurrent Mania Course – Role of Periventricular Leukomalacia

2021 ◽  
Author(s):  
Harkishan Mamtani ◽  
Lakshmi Shiva ◽  
Madhuri H Nanjundaswamy ◽  
Nitish Kamble ◽  
Chandrajit Prasad ◽  
...  
Keyword(s):  
Affective Disorder ◽  
Periventricular Leukomalacia ◽  
Bipolar Affective Disorder ◽  
Treatment Resistance

Bipolar affective disorder in the postnatal period: investigating the role of sleep

2010 ◽  
Vol 12 (5) ◽  
pp. 568-578 ◽  
Author(s):  
Justin L C Bilszta ◽  
Denny Meyer ◽  
Anne E Buist
Keyword(s):  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Postnatal Period

Shoplifting in the Mentally Ill: The role of bipolar affective disorder and mental retardation

2005 ◽  
Vol 45 (4) ◽  
pp. 317-320 ◽  
Author(s):  
Rachel S Y Cheng ◽  
Candy Lin ◽  
Marcella L Y Fok ◽  
Chi-Ming Leung
Keyword(s):  
Mental Retardation ◽  
Affective Disorder ◽  
Mentally Ill ◽  
Matched Control ◽  
Psychiatric Patients ◽  
Bipolar Affective Disorder ◽  
Mental Illnesses ◽  
Control Group ◽  
University Department

This study explores shoplifting behaviour in mentally ill patients, and evaluates the association between shoplifting and different mental illnesses in a local Chinese population. A comparison is made between shoplifting offenders and a matched control group of non-offenders among the psychiatric patients registered at a university department of psychiatry. Major depression, bipolar affective disorder (BAD) and mental retardation (MR) are the most common diagnoses among mentally ill shoplifters, while patients with a diagnosis of BAD or MR are at higher risk of committing an offence than patients with other diagnoses. Bipolar affective disorder has not been described as a risk factor for shoplifting behaviour in the psychiatric literature. Such a possibility should be seriously considered in the psychiatric assessment of shoplifting cases.

scholarly journals Treatment resistance in psychiatry: state of the art and new directions

2021 ◽  
Author(s):  
Oliver D. Howes ◽  
Michael E. Thase ◽  
Toby Pillinger
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Treatment Resistance ◽  
Psychiatric Research ◽  
Total Output ◽  
Post Traumatic Stress ◽  
Major Depressive ◽  
Compulsive Disorder

AbstractTreatment resistance affects 20–60% of patients with psychiatric disorders; and is associated with increased healthcare burden and costs up to ten-fold higher relative to patients in general. Whilst there has been a recent increase in the proportion of psychiatric research focussing on treatment resistance (R2 = 0.71, p < 0.0001), in absolute terms this is less than 1% of the total output and grossly out of proportion to its prevalence and impact. Here, we provide an overview of treatment resistance, considering its conceptualisation, assessment, epidemiology, impact, and common neurobiological models. We also review new treatments in development and future directions. We identify 23 consensus guidelines on its definition, covering schizophrenia, major depressive disorder, bipolar affective disorder, and obsessive compulsive disorder (OCD). This shows three core components to its definition, but also identifies heterogeneity and lack of criteria for a number of disorders, including panic disorder, post-traumatic stress disorder, and substance dependence. We provide a reporting check-list to aid comparisons across studies. We consider the concept of pseudo-resistance, linked to poor adherence or other factors, and provide an algorithm for the clinical assessment of treatment resistance. We identify nine drugs and a number of non-pharmacological approaches being developed for treatment resistance across schizophrenia, major depressive disorder, bipolar affective disorder, and OCD. Key outstanding issues for treatment resistance include heterogeneity and absence of consensus criteria, poor understanding of neurobiology, under-investment, and lack of treatments. We make recommendations to address these issues, including harmonisation of definitions, and research into the mechanisms and novel interventions to enable targeted and personalised therapeutic approaches.

scholarly journals Considerations on assisted resilience and individualized therapy in bipolar affective disorder, with a clinical case exemplification

2015 ◽  
Vol 88 (4) ◽  
pp. 462-467 ◽  
Author(s):  
Alexandra Bolos
Keyword(s):  
Bipolar Disorder ◽  
Affective Disorder ◽  
Clinical Case ◽  
Bipolar Affective Disorder ◽  
Indirect Costs ◽  
Economic Consequences ◽  
Case Presentation ◽  
Affective Symptoms ◽  
Psychosocial Consequences

Morbidity, mortality and economic consequences of bipolar affective disorder are very important to be evaluated because many of the costs entailed by this psychiatric disorder come from indirect costs due to inadequate diagnosis and treatment and from the characteristics of the affective symptoms itself. Psychotherapy focuses on diagnosis and the newest pharmacotherapy determines a decreasing of the morbidity of the disorder and also of its social and economic burden . However, more studies are necessary, with more heterogeneous patients, to find more predictors regarding the psychosocial consequences and to find more information about the prognosis of the bipolar disorder.In this context, in this paper we discuss the role of assisted resilience and the individualization of the therapy of bipolar affective disorder, especially that the resilience must be seen as a continuum and can be used anytime and in any situation, according to the theory of Geanellos. This idea is reflected in a case presentation of a patient with the diagnosis of bipolar disorder.

The role of the arginine-nitric oxide pathway in the pathogenesis of bipolar affective disorder

2004 ◽  
Vol 254 (1) ◽  
pp. 43-47 ◽  
Author(s):  
Medaim Yanik ◽  
H�seyin Vural ◽  
Hamdi Tutkun ◽  
S�leyman Salih Zoroglu ◽  
Haluk Asuman Savas ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Nitric Oxide Pathway

Possible Role of Nitric Oxide and Adrenomedullin in Bipolar Affective Disorder

2002 ◽  
Vol 45 (2) ◽  
pp. 57-61 ◽  
Author(s):  
Haluk A. Savaş ◽  
Hasan Herken ◽  
Muhittin Yürekli ◽  
Efkan Uz ◽  
Hamdi Tutkun ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Affective Disorder ◽  
Bipolar Affective Disorder

scholarly journals The Role of Clozapine as a Mood Regulator in the Treatment of Rapid Cycling Bipolar Affective Disorder

2019 ◽  
Author(s):  
Oguzhan Kilincel ◽  
Senay Kilincel ◽  
Cem Gunduz ◽  
Sengul Cangur ◽  
Cengiz Akkaya
Keyword(s):  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Rapid Cycling

Patterns of treatment resistance in bipolar affective disorder

1993 ◽  
Vol 88 (2) ◽  
pp. 121-123 ◽  
Author(s):  
A. J. Cole ◽  
J. Scott ◽  
I. N. Ferrier ◽  
D. Eccleston
Keyword(s):  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Treatment Resistance
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