Symptomatic improvement of acute mania associated with a single session of electroconvulsive therapy: a proposed concept of neuroversion

2021 ◽  
Author(s):  
Amílcar Silva‐dos‐Santos ◽  
Miguel Bruno Sales ◽  
Diana Venda
Keyword(s):  
Electroconvulsive Therapy ◽  
Symptomatic Improvement ◽  
Acute Mania ◽  
Single Session

Electroconvulsive Therapy in Treatment-resistant Schizophrenia: Prediction of Response and the Nature of Symptomatic Improvement

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
W. Chanpattana ◽  
H. Sackeim
Keyword(s):  
Clinical Features ◽  
Electroconvulsive Therapy ◽  
Negative Symptoms ◽  
Critical Role ◽  
Poor Response ◽  
Symptomatic Improvement ◽  
Treatment Resistant ◽  
Affective Symptoms ◽  
Duration Of Illness ◽  
Long Duration

The clinical features of patients with schizophrenia who respond to electroconvulsive therapy (ECT) are uncertain. There is also little information on the nature of symptomatic improvement with this treatment. Using a standardized protocol, 253 patients with treatment-resistant schizophrenia (TRS) were treated with combination ECT and flupenthixol, and 138 (54.5%) patients met response criteria. Independent of gender, duration of the current episode and severity of baseline negative symptoms were predictive of outcome. Duration of illness had weak relations with outcome and only among females. There were marked sex differences in other clinical features and symptoms associated with response. In contrast, no gender differences were observed in the nature of symptomatic improvement. Treatment resulted in marked improvement in specific positive symptoms, with an intermediate effect on affective symptoms, and no effect or worsening of specific negative symptoms. The findings challenge recommendations that long duration of illness or absence of affective symptoms portends poor response to ECT in patients with TRS. Gender may play a critical role in determining the features of the illness that predict outcome.

scholarly journals Acute Mania and Catatonia in a Teenager Successfully Treated with Electroconvulsive Therapy and Diagnosed with Turner Syndrome and Bipolar Disorder

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Maria Ygland Rödström ◽  
Björn Axel Johansson ◽  
Beata Bäckström ◽  
Pouya Movahed ◽  
Carl-Magnus Forslund ◽  
...  
Keyword(s):  
Turner Syndrome ◽  
Electroconvulsive Therapy ◽  
Psychiatric Symptoms ◽  
Manic Episode ◽  
Acute Mania ◽  
Successful Outcome ◽  
Psychotic Symptoms ◽  
X Chromosomes ◽  
Efficient Treatment ◽  
Affective Symptoms

Background. Turner syndrome (TS) is an X-linked chromosomal abnormality with a global prevalence of 1/2000 live-born girls. The physiological symptoms of TS have been thoroughly characterized, but only a few studies have described associated psychiatric symptoms. We report a case of an adolescent girl who presented with acute mania with psychotic features and was successfully treated with electroconvulsive therapy (ECT). She was subsequently diagnosed with bipolar syndrome and TS. Case Presentation. A 17-year-old girl presented to us with manic symptoms, including disorganized speech, auditory hallucinations, and affect lability. Initially, she was treated with antipsychotics and benzodiazepines, whereby the positive affective symptoms declined. However, the psychotic symptoms progressed, and she developed a catatonic state. ECT was started 6 days after admission, with improvement after two treatments. When ECT was tapered after seven sessions, she relapsed, and the treatment was extended to twelve sessions, with successful outcome. Following discharge, she was diagnosed with TS with partial loss on one of the X-chromosomes (46X, del (X)(p21)), which might have contributed to the development of her sudden acute manic episode. Conclusions. This case demonstrates for the first time that ECT may be a safe and efficient treatment strategy for acute mania in adolescents with concomitant TS and that severely affected adolescents may require a prolonged series with gradual tapering of ECT. The present case also demonstrates a possible association between TS and bipolar syndrome and that the clinical presentation of a manic episode in a patient with this comorbidity could be more complex and the treatment response slower.

The Development of Swallowing Respiratory Coordination

2009 ◽  
Vol 18 (1) ◽  
pp. 19-24
Author(s):  
Maggie-Lee Huckabee
Keyword(s):  
Cortical Activation ◽  
First Year ◽  
Healthy Children ◽  
Nasal Airflow ◽  
Single Session ◽  
Primary Finding ◽  
Patterns Of Behavior ◽  
Cortical Modulation ◽  
First Year Of Life ◽  
Swallowing Apnea

Abstract Research exists that evaluates the mechanics of swallowing respiratory coordination in healthy children and adults as well and individuals with swallowing impairment. The research program summarized in this article represents a systematic examination of swallowing respiratory coordination across the lifespan as a means of behaviorally investigating mechanisms of cortical modulation. Using time-locked recordings of submental surface electromyography, nasal airflow, and thyroid acoustics, three conditions of swallowing were evaluated in 20 adults in a single session and 10 infants in 10 sessions across the first year of life. The three swallowing conditions were selected to represent a continuum of volitional through nonvolitional swallowing control on the basis of a decreasing level of cortical activation. Our primary finding is that, across the lifespan, brainstem control strongly dictates the duration of swallowing apnea and is heavily involved in organizing the integration of swallowing and respiration, even in very early infancy. However, there is evidence that cortical modulation increases across the first 12 months of life to approximate more adult-like patterns of behavior. This modulation influences primarily conditions of volitional swallowing; sleep and naïve swallows appear to not be easily adapted by cortical regulation. Thus, it is attention, not arousal that engages cortical mechanisms.

A Case of Catatonia in a 14-Year-Old Girl with Schizophrenia Treated with Electroconvulsive Therapy

2013 ◽  
Vol 41 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Frank Häßler ◽  
Olaf Reis ◽  
Steffen Weirich ◽  
Jacqueline Höppner ◽  
Birgit Pohl ◽  
...  
Keyword(s):  
Case Report ◽  
Treatment Response ◽  
Electroconvulsive Therapy ◽  
Rating Scale ◽  
Combined Treatment ◽  
Adolescent Patient

This article presents a case of a 14-year-old female twin with schizophrenia who developed severe catatonia following treatment with olanzapine. Under a combined treatment with amantadine, electroconvulsive therapy (ECT), and (currently) ziprasidone alone she improved markedly. Severity and course of catatonia including treatment response were evaluated with the Bush-Francis Catatonia Rating Scale (BFCRS). This case report emphasizes the benefit of ECT in the treatment of catatonic symptoms in an adolescent patient with schizophrenic illness.

Electroconvulsive Therapy: Something for Everyone

1994 ◽  
Vol 39 (1) ◽  
pp. 39-40
Author(s):  
P. V. Nickell
Keyword(s):  
Electroconvulsive Therapy
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