scholarly journals The role of different patterns of psychomotor symptoms in major depressive episode: Pooled analysis of the BRIDGE and BRIDGE‐II‐MIX cohorts

2019 ◽  
Vol 21 (8) ◽  
pp. 785-793 ◽  
Author(s):  
Margherita Barbuti ◽  
Cecilia Mainardi ◽  
Isabella Pacchiarotti ◽  
Norma Verdolini ◽  
Giuseppe Maccariello ◽  
...  
Keyword(s):  
Depressive Episode ◽  
Major Depressive Episode ◽  
Pooled Analysis ◽  
Major Depressive ◽  
Psychomotor Symptoms

scholarly journals Structural abnormalities associated with poor outcome of a major depressive episode: The role of thalamus

2020 ◽  
Vol 305 ◽  
pp. 111158
Author(s):  
JM. Batail ◽  
J. Coloigner ◽  
M. Soulas ◽  
G. Robert ◽  
C. Barillot ◽  
...  
Keyword(s):  
Depressive Episode ◽  
Major Depressive Episode ◽  
Major Depressive ◽  
Poor Outcome ◽  
Structural Abnormalities

scholarly journals Antidepressant-Resistant Depression and Antidepressant-Associated Suicidal Behaviour: The Role of Underlying Bipolarity

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Zoltan Rihmer ◽  
Xenia Gonda
Keyword(s):  
Depressive Episode ◽  
Suicidal Behaviour ◽  
Major Depressive Episode ◽  
Age At Onset ◽  
Early Age ◽  
Bipolar Spectrum ◽  
Clinical Markers ◽  
Major Depressive ◽  
Resistant Depression

The complex relationship between the use of antidepressants and suicidal behaviour is one of the hottest topics of our contemporary psychiatry. Based on the literature, this paper summarizes the author's view on antidepressant-resistant depression and antidepressant-associated suicidal behaviour. Antidepressant-resistance, antidepressant-induced worsening of depression, antidepressant-associated (hypo)manic switches, mixed depressive episode, and antidepressant-associated suicidality among depressed patients are relatively most frequent in bipolar/bipolar spectrum depression and in children and adolescents. As early age at onset of major depressive episode and mixed depression are powerful clinical markers of bipolarity and the manic component of bipolar disorder (and possible its biological background) shows a declining tendency with age antidepressant-resistance/worsening, antidepressant-induced (hypo)manic switches and “suicide-inducing” potential of antidepressants seem to be related to the underlying bipolarity.

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