scholarly journals Altered N170 and mood symptoms in bipolar disorder: An electrophysiological study of configural face processing

2017 ◽  
Vol 20 (5) ◽  
pp. 477-487 ◽  
Author(s):  
Ivy F Tso ◽  
Tyler B Grove ◽  
Savanna A Mueller ◽  
Lisa O'Donnell ◽  
Jinsoo Chun ◽  
...  
2016 ◽  
Vol 22 (6) ◽  
pp. 652-661 ◽  
Author(s):  
Nicole Joshua ◽  
Tamsyn E. Van Rheenen ◽  
David J Castle ◽  
Susan L. Rossell

AbstractObjectives: Use of appropriate face processing strategies is important for facial emotion recognition, which is known to be impaired in schizophrenia (SZ) and bipolar disorder (BD). There is preliminary evidence of abnormalities in the use of face processing strategies in the former, but there has been no explicit attempt to assess face processing in patients with BD. Methods: Twenty-eight BD I, 28 SZ, and 28 healthy control participants completed tasks assessing featural and configural face processing. The facial inversion effect was used as a proxy of second order configural face processing and compared to featural face processing performance (which is known to be relatively less affected by facial inversion). Results: Controls demonstrated the usual second-order inversion pattern. In the BD group, the absence of a second-order configural inversion effect in the presence of a disproportionate bias toward a featural inversion effect was evident. Despite reduced accuracy performance in the SZ group compared to controls, this group unexpectedly showed a normal second-order configural accuracy inversion pattern. This was in the context of a reverse inversion effect for response latency, suggesting a speed-versus-accuracy trade-off. Conclusions: To our knowledge, this is the first study to explicitly examine and contrast face processing in BD and SZ. Our findings indicate a generalized impairment on face processing tasks in SZ, and the presence of a second-order configural face processing impairment in BD. It is possible that these face processing impairments represent a catalyst for the facial emotion recognition deficits that are commonly reported in the literature. (JINS, 2016, 22, 652–661)


2017 ◽  
Vol 23 (3) ◽  
pp. 287-291 ◽  
Author(s):  
Tamsyn E. Van Rheenen ◽  
Nicole Joshua ◽  
David J Castle ◽  
Susan L. Rossell

AbstractObjectives: Emotion recognition impairments have been demonstrated in schizophrenia (Sz), but are less consistent and lesser in magnitude in bipolar disorder (BD). This may be related to the extent to which different face processing strategies are engaged during emotion recognition in each of these disorders. We recently showed that Sz patients had impairments in the use of both featural and configural face processing strategies, whereas BD patients were impaired only in the use of the latter. Here we examine the influence that these impairments have on facial emotion recognition in these cohorts. Methods: Twenty-eight individuals with Sz, 28 individuals with BD, and 28 healthy controls completed a facial emotion labeling task with two conditions designed to separate the use of featural and configural face processing strategies; part-based and whole-face emotion recognition. Results: Sz patients performed worse than controls on both conditions, and worse than BD patients on the whole-face condition. BD patients performed worse than controls on the whole-face condition only. Conclusions: Configural processing deficits appear to influence the recognition of facial emotions in BD, whereas both configural and featural processing abnormalities impair emotion recognition in Sz. This may explain discrepancies in the profiles of emotion recognition between the disorders. (JINS, 2017, 23, 287–291)


2015 ◽  
Vol 29 (2) ◽  
pp. 197-204 ◽  
Author(s):  
Eric Fakra ◽  
Elisabeth Jouve ◽  
Fabrice Guillaume ◽  
Jean-Michel Azorin ◽  
Olivier Blin

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Anja W. M. M. Stevens ◽  
Stasja Draisma ◽  
Peter J. J. Goossens ◽  
Birit F. P. Broekman ◽  
Adriaan Honig ◽  
...  

Abstract Background and rationale Although it has been suggested that pregnancy may influence the course of bipolar disorder (BD), studies show contradictory results. Until now, no studies included a finegrained validated method to report mood symptoms on a daily basis, such as the lifechart method (LCM). The aim of the present study is to investigate the course of BD during pregnancy by comparing LCM scores of pregnant and non-pregnant women. Methods Study design: Comparison of LCM scores of two prospective observational BD cohort studies, a cohort of pregnant women (n = 34) and a cohort of non-pregnant women of childbearing age (n = 52). Main study parameters are: (1) proportions of symptomatic and non-symptomatic days; (2) symptom severity, frequency, and duration of episodes; (3) state sequences, longitudinal variation of symptom severity scores. Results No differences in clinical course variables (symptomatic days, average severity scores, frequency, and duration of episodes in BD were found between pregnant and non-pregnant women. With a combination of State Sequence Analysis (SSA) and cluster analysis on the sequences of daily mood scores three comparable clusters were found in both samples: euthymic, moderately ill and severely ill. The distribution differences between pregnant and non-pregnant women were significant, with a majority of the pregnant women (68%) belonging to the moderately ill cluster and a majority of the non-pregnant women (46%) to the euthymic cluster. In pregnant women the average daily variation in mood symptoms as assessed with Shannon’s entropy was less than in non-pregnant women (respectively 0.43 versus 0.56). Conclusions Although the use of daily mood scores revealed no difference in overall course of BD in pregnant versus non-pregnant women, more pregnant than non-pregnant women belonged to the moderately ill cluster, and during pregnancy the variation in mood state was less than in non-pregnant women. Further research is necessary to clarify these findings.


2007 ◽  
Vol 68 (08) ◽  
pp. 1237-1245 ◽  
Author(s):  
Gregory E. Simon ◽  
Mark S. Bauer ◽  
Evette J. Ludman ◽  
Belinda H. Operskalski ◽  
Jürgen Unützer

2020 ◽  
Vol 273 ◽  
pp. 517-523
Author(s):  
Esther Ching-Lan Lin ◽  
Marc J. Weintraub ◽  
David J. Miklowitz ◽  
Po-See Chen ◽  
Shih-Kai Lee ◽  
...  

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