The predictive validity of bipolar at-risk (prodromal) criteria in help-seeking adolescents and young adults: a prospective study

2014 ◽  
Vol 16 (5) ◽  
pp. 493-504 ◽  
Author(s):  
Andreas Bechdolf ◽  
Aswin Ratheesh ◽  
Sue M Cotton ◽  
Barnaby Nelson ◽  
Andrew M Chanen ◽  
...  
2012 ◽  
Vol 51 (1) ◽  
pp. 86-92 ◽  
Author(s):  
Andrea B. Goldschmidt ◽  
Melanie Wall ◽  
Katie A. Loth ◽  
Daniel Le Grange ◽  
Dianne Neumark-Sztainer

2008 ◽  
Vol 29 (2) ◽  
pp. 182-192 ◽  
Author(s):  
Julie H. Goldberg ◽  
Susan Millstein ◽  
Alan Schwartz ◽  
Bonnie Halpern-Felsher

2010 ◽  
Vol 127 (1-3) ◽  
pp. 316-320 ◽  
Author(s):  
Andreas Bechdolf ◽  
Barnaby Nelson ◽  
Sue M. Cotton ◽  
Andrew Chanen ◽  
Andrew Thompson ◽  
...  

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
A. Bechdolf ◽  
B. Nelson ◽  
S.M. Cotton ◽  
A. Chanen ◽  
A. Thompson ◽  
...  

Introduction:We have developed ultra-high risk criteria for bipolar affective disorder (bipolar at-risk - BAR) which include general criteria such as being in the peak age range of the onset of the disorder and a combination of specific criteria including sub-threshold mania, depressive symptoms, cyclothymic features and genetic risk. In the current study, the predictive and discriminant validity of these criteria were tested in help seeking adolescents and young adults.Method:This medical file-audit study was conducted at ORYGEN Youth Health (OYH), a public mental health program for young people aged between 15 and 24 years and living in metropolitan Melbourne, Australia. BAR criteria were applied to the intake assessments of all non-psychotic patients who were being treated in OYH on 31 January.08. All entries were then checked for conversion criteria. Hypomania/mania related additions or alterations to existing treatments or initiation of new treatment by the treating psychiatrist served as conversion criteria to mania.Results:The BAR criteria were applied to 173 intake assessments. Of these, 22 patients (12.7%) met BAR criteria. The follow-up period of the sample was 265.5 days on average (SD 214.7). There were significantly more cases in the BAR group (22.7%, n = 5) than in the non-BAR group (0.7%, n = 1) who met conversion criteria (p < .001).Conclusions:These findings support the notion that people who develop a first episode of mania can be identified during the prodromal phase. The proposed criteria need further evaluation in prospective clinical trials.


2011 ◽  
Vol 36 (4) ◽  
pp. 476-487 ◽  
Author(s):  
A. Casier ◽  
L. Goubert ◽  
M. Theunis ◽  
D. Huse ◽  
F. De Baets ◽  
...  

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