scholarly journals Cortical thickness differences between bipolar depression and major depressive disorder

2014 ◽  
Vol 16 (4) ◽  
pp. 378-388 ◽  
Author(s):  
Martin J Lan ◽  
Binod Thapa Chhetry ◽  
Maria A Oquendo ◽  
M Elizabeth Sublette ◽  
Gregory Sullivan ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Cortical Thickness ◽  
Bipolar Depression ◽  
Major Depressive

scholarly journals Asymmetry in cortical thickness and subcortical volume in treatment-naïve major depressive disorder

2019 ◽  
Vol 21 ◽  
pp. 101614 ◽  
Author(s):  
Zhiwei Zuo ◽  
Shuhua Ran ◽  
Yao Wang ◽  
Chang Li ◽  
Qi Han ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Cortical Thickness ◽  
Major Depressive ◽  
Treatment Naïve ◽  
Subcortical Volume

scholarly journals An investigation of cortical thickness and antidepressant response in major depressive disorder: A CAN-BIND study report

2020 ◽  
Vol 25 ◽  
pp. 102178
Author(s):  
Jee Su Suh ◽  
Luciano Minuzzi ◽  
Pradeep Reddy Raamana ◽  
Andrew Davis ◽  
Geoffrey B. Hall ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Cortical Thickness ◽  
Antidepressant Response ◽  
Major Depressive ◽  
Study Report

scholarly journals Electroconvulsive Therapy Induces Cortical Morphological Alterations in Major Depressive Disorder Revealed with Surface-Based Morphometry Analysis

2019 ◽  
Vol 29 (07) ◽  
pp. 1950005 ◽  
Author(s):  
Jinping Xu ◽  
Jiaojian Wang ◽  
Tongjian Bai ◽  
Xiaodong Zhang ◽  
Tian Li ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Surface Area ◽  
Cortical Thickness ◽  
Electroconvulsive Therapy ◽  
Therapeutic Efficacy ◽  
Support Vector ◽  
Major Depressive ◽  
Before And After ◽  
Surface Based Morphometry

Although electroconvulsive therapy (ECT) is one of the most effective treatments for major depressive disorder (MDD), the mechanism underlying the therapeutic efficacy and side effects of ECT remains poorly understood. Here, we investigated alterations in the cortical morphological measurements including cortical thickness (CT), surface area (SA), and local gyrification index (LGI) in 23 MDD patients before and after ECT. Furthermore, multivariate pattern analysis using linear support vector machine (SVM) was applied to investigate whether the changed morphological measurements can be effective indicators for therapeutic efficacy of ECT. Surface-based morphometry (SBM) analysis found significantly increased vertex-wise and regional cortical thickness (CT) and surface area (SA) in widespread regions, mainly located in the left insula (INS) and left fusiform gyrus, as well as hypergyrification in the left middle temporal gyrus (MTG) in MDD patients after ECT. Partial correlational analyses identified associations between the morphological properties and depressive symptom scores and impaired memory scores. Moreover, SVM result showed that the changed morphological measurements were effective to classify the MDD patients before and after ECT. Our findings suggested that ECT may enhance cortical neuroplasticity to facilitate neurogenesis to remit depressive symptoms and to impair delayed memory. These findings indicated that the cortical morphometry is a good index for therapeutic efficacy of ECT.

Salience-thalamic circuit uncouples in major depressive disorder, but not in bipolar depression

2020 ◽  
Vol 269 ◽  
pp. 43-50 ◽  
Author(s):  
Can Zeng ◽  
Zhimin Xue ◽  
Brendan Ross ◽  
Manqi Zhang ◽  
Zhening Liu ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Bipolar Depression ◽  
Major Depressive
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