Predicting bipolar disorder on the basis of phenomenology: implications for prevention and early intervention

2013 ◽  
Vol 16 (5) ◽  
pp. 455-470 ◽  
Author(s):  
Gin S Malhi ◽  
Danielle M Bargh ◽  
Carissa M Coulston ◽  
Pritha Das ◽  
Michael Berk
2016 ◽  
Vol 22 (3) ◽  
pp. 176-185 ◽  
Author(s):  
Josephine Loftus ◽  
Bruno Etain ◽  
Jan Scott

SummaryWe offer a contemporary review of studies of the offspring of parents with bipolar disorder and explore the clinical characteristics of these populations. We discuss how different methodological approaches may influence study findings and may explain some of the heterogeneity in the results reported. We also highlight some of the environmental risk factors that may increase the likelihood of transition from an ‘at-risk’ or high-risk state to bipolar disorder. Last, we briefly discuss the implications of study findings for early intervention strategies and comment on such issues as genetic counselling and primary and early secondary prevention programmes.


Author(s):  
Vicent Balanzá-Martínez ◽  
María Lacruz ◽  
Rafael Tabarés-Seisdedos

2021 ◽  
Vol 8 (1) ◽  
pp. 64-75 ◽  
Author(s):  
Gayatri Saraf ◽  
Ehsan Moazen-Zadeh ◽  
Jairo Vinícius Pinto ◽  
Kimia Ziafat ◽  
Ivan J Torres ◽  
...  

Author(s):  
Ajeet B. Singh ◽  
Harris A. Eyre ◽  
Edward Callaly ◽  
Michael Berk

The early intervention in psychiatry paradigm has offered the promise of improved tailored treatment. While pioneered in early psychosis, lines of evidence also suggest utility in early bipolar. A challenge is that the emergence of elevated states may post-date depression—preventing early diagnosis. Nonetheless, data suggests neuroprogression and an escalating diathesis to relapse occurs with successive episodes which may be impeded by early intervention. Mitigating psychosocial impacts, improving engagement, reducing the consequences of the progressive nature of the disorder, and enhancing adherence are key potential dividends of early intervention. This chapter provides an overview of the current literature, expert clinical opinions, and hints at future directions pertinent to early intervention. As genomics, informatics, and better appreciation of the importance of diet and lifestyle gain salience, there’s hope for a future rich with technologically enhanced tools to both sooner detect and intervene in early stage bipolar disorders to mitigate consequences.


2014 ◽  
Vol 152-154 ◽  
pp. 403-408 ◽  
Author(s):  
Lars Vedel Kessing ◽  
Hanne Vibe Hansen ◽  
Ellen Margrethe Christensen ◽  
Henrik Dam ◽  
Christian Gluud ◽  
...  

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