Prescribers' compliance with summary of product characteristics of dabigatran, rivaroxaban and apixaban—A European comparative drug utilization study

2020 ◽  
Author(s):  
Marietta Rottenkolber ◽  
Sven Schmiedl ◽  
Luisa Ibánez ◽  
Mònica Sabaté ◽  
Elena Ballarín ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Product Characteristics ◽  
Drug Utilization Study ◽  
Summary Of Product Characteristics

A drug utilization study of oral hypoglycemic drugs and insulin in diabetic patients: Face to face with reality

2019 ◽  
Vol 11 (3) ◽  
pp. 25-29
Author(s):  
Suyog S Chopade ◽  
◽  
Rahul P Bhavsar ◽  
Devendra R Chaudhari ◽  
Bapurao M Bite ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Diabetic Patients ◽  
Drug Utilization Study ◽  
Face To Face ◽  
Oral Hypoglycemic Drugs

scholarly journals Automatic Extraction of Adverse Drug Reactions from Summary of Product Characteristics

2021 ◽  
Vol 11 (6) ◽  
pp. 2663
Author(s):  
Zhengru Shen ◽  
Marco Spruit
Keyword(s):  
Natural Language Processing ◽  
Natural Language ◽  
Adverse Drug Reactions ◽  
Language Processing ◽  
European Medicines Agency ◽  
Drug Reactions ◽  
Clinical Practices ◽  
Product Characteristics ◽  
Textual Information ◽  
Summary Of Product Characteristics

The summary of product characteristics from the European Medicines Agency is a reference document on medicines in the EU. It contains textual information for clinical experts on how to safely use medicines, including adverse drug reactions. Using natural language processing (NLP) techniques to automatically extract adverse drug reactions from such unstructured textual information helps clinical experts to effectively and efficiently use them in daily practices. Such techniques have been developed for Structured Product Labels from the Food and Drug Administration (FDA), but there is no research focusing on extracting from the Summary of Product Characteristics. In this work, we built a natural language processing pipeline that automatically scrapes the summary of product characteristics online and then extracts adverse drug reactions from them. Besides, we have made the method and its output publicly available so that it can be reused and further evaluated in clinical practices. In total, we extracted 32,797 common adverse drug reactions for 647 common medicines scraped from the Electronic Medicines Compendium. A manual review of 37 commonly used medicines has indicated a good performance, with a recall and precision of 0.99 and 0.934, respectively.

scholarly journals Drug utilization study of antihypertensive drugs and prevalence of blood pressure control in adult hypertensive patients based on JNC VIII guidelines in a tertiary care hospital: a cross sectional study

2019 ◽  
Vol 8 (2) ◽  
pp. 245
Author(s):  
Saumya Ramadas ◽  
M. B. Sujatha ◽  
M. A. Andrews ◽  
Sanalkumar K. B.
Keyword(s):  
Blood Pressure ◽  
Combination Therapy ◽  
Drug Utilization ◽  
Antihypertensive Drug ◽  
Blood Pressure Control ◽  
Antihypertensive Drugs ◽  
Pressure Control ◽  
Antihypertensive Drug Therapy ◽  
Care Hospital ◽  
Drug Utilization Study

Background: Hypertension is a major independent risk factor for coronary artery disease, congestive heart failure, stroke, chronic kidney disease and peripheral vascular diseases if left untreated. Drug utilization study of antihypertensive drugs and the study on prevalence of blood pressure control would help in reducing the burden of the disease and health expenditure.Methods: The study was conducted in the Outpatient Department of Medicine in Government Medical College, Thrissur. Patients aged 18yrs or above diagnosed with hypertension, on antihypertensive drugs were enrolled in the study. Patients suffering from secondary hypertension and acutely ill were excluded. Patients were enrolled after taking an informed consent. Demographic data, present treatment for hypertension, associated co- morbid conditions if any, and treatment of the same were recorded. BP was recorded, and cost of treatment was calculated using CIMS.Results: A total of 250 patients were included in the study. Mono therapy was used in 64.8% patients and combination therapy in 35.2%. Overall drug utilization pattern showed that CCBs (42.8%) were most commonly prescribed, followed by ACEIs (32.4%) and ARBs (29.2%). Most commonly prescribed combination therapy was ACE I + BB (29.3%), followed by ARB + CCB (21.3%). Mean cost of antihypertensive drug therapy was 3057.8 Rs / yr. Recommended target BP was achieved in 49.6% of patients.Conclusions: The prescription pattern of antihypertensive drug was in accordance to the JNC-VIII guidelines. The blood pressure target was achieved only in less than 50% of patients.

Use of Pregabalin – A Nationwide Pharmacoepidemiological Drug Utilization Study with Focus on Abuse Potential

2016 ◽  
Vol 49 (04) ◽  
pp. 155-161 ◽  
Author(s):  
O. Schjerning ◽  
A. Pottegård ◽  
P. Damkier ◽  
M. Rosenzweig ◽  
J. Nielsen
Keyword(s):  
Drug Utilization ◽  
Abuse Potential ◽  
Drug Utilization Study
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