scholarly journals Intravenous Lipid Emulsion as an Antidote for the Treatment of Acute Poisoning: A Bibliometric Analysis of Human and Animal Studies

2016 ◽  
Vol 119 (5) ◽  
pp. 512-519 ◽  
Author(s):  
Sa'ed H. Zyoud ◽  
W. Stephen Waring ◽  
Samah W. Al-Jabi ◽  
Waleed M. Sweileh ◽  
Belal Rahhal ◽  
...  
Keyword(s):  
Bibliometric Analysis ◽  
Lipid Emulsion ◽  
Animal Studies ◽  
Acute Poisoning ◽  
Intravenous Lipid Emulsion

scholarly journals Intravenous lipid emulsion in treatment of cardiocirculatory disturbances caused by glyphosate-surfactant herbicide poisoning

2016 ◽  
Vol 73 (4) ◽  
pp. 390-392 ◽  
Author(s):  
Jasmina Jovic-Stosic ◽  
Vesna Putic ◽  
Natasa Perkovic-Vukcevic ◽  
Gordana Babic ◽  
Snezana Djordjevic ◽  
...  
Keyword(s):  
Case Report ◽  
Lipid Emulsion ◽  
Genetically Modified Crops ◽  
Acute Poisoning ◽  
Commercial Products ◽  
Arterial Blood Gas ◽  
Intravenous Lipid Emulsion ◽  
Arterial Blood ◽  
Low Toxicity ◽  
Glyphosate Herbicide

Introduction. Glyphosate is the first widely used herbicide against weed in genetically modified crops. Though glyphosate itself has a low toxicity, commercial products are more dangerous because of increased toxicity due to surfactants addition. There is no specific antidote for the poisoning with glyphosate-surfactant (Gly-SH). In recent times, the efficacy of intravenous lipid emulsion (ILE) administration for the treatment of acute poisoning caused by Gly- SH has been investigated. Case Report. A 50-year-old man was admitted 3 hours after self-poisoning with herbicide containing glyphosate and polyoxyethyleneamine, as a surfactant. On admission, the patient was in a coma, hypotensive (80/50 mmHg) and without spontaneous breathing. Electrocardiogram showed widecomplex tachycardia, and arterial blood gas (ABG) revealed acidosis (pH 7.07). Conventional treatment included mechanical ventilation, intravenous fluids, bicarbonate and dopamine. As there was no improvement, ILE was started. The patient received 100 mL of 20% Intralipid? bolus followed by infusion of 400 mL over 20 minutes. Prior to expiration of infusion, a gradual rise in blood pressure was noted, and within 2 hours sinus rhythm was restored. Conclusion. This case report suggests that the use of ILE may be an additional option for the treatment of cardiocirculatory disturbances caused by commercial products of glyphosate herbicide.

The use of intravenous lipid emulsion therapy in acute methamphetamine toxicity

2016 ◽  
Vol 34 (8) ◽  
pp. 1732.e3-1732.e4 ◽  
Author(s):  
James Tse ◽  
Kevin Ferguson ◽  
K. Scott Whitlow ◽  
Karly Erickson
Keyword(s):  
Lipid Emulsion ◽  
Intravenous Lipid Emulsion

Intravenous Lipid Emulsion as Salvage Treatment for Haloperidol Toxicity

2020 ◽  
Vol 28 (5) ◽  
pp. e612-e614
Author(s):  
Mohammed T. Awad ◽  
Mujahed Alkhathlan ◽  
Samantha L. Spetz ◽  
Michael Conley ◽  
Ragheb Assaly
Keyword(s):  
Lipid Emulsion ◽  
Salvage Treatment ◽  
Intravenous Lipid Emulsion

Low‐dose intravenous lipid emulsion as a safe treatment for lipophilic intoxications in five cats

2018 ◽  
Vol 6 (4) ◽  
Author(s):  
Marco Pelizzola ◽  
Clara Mattavelli ◽  
Roberta Troìa ◽  
Elsa Murgia ◽  
Massimo Giunti
Keyword(s):  
Lipid Emulsion ◽  
Low Dose ◽  
Safe Treatment ◽  
Intravenous Lipid Emulsion

Intravenous lipid emulsion prolongs survival in rats intoxicated with digoxin

2016 ◽  
Vol 34 (6) ◽  
pp. 1112-1116 ◽  
Author(s):  
Bülent Serhan Yurtlu ◽  
Şule Özbilgin ◽  
Derya Arslan Yurtlu ◽  
Nilay Boztaş ◽  
Gonca Kamacı ◽  
...  
Keyword(s):  
Lipid Emulsion ◽  
Intravenous Lipid Emulsion

Intravenous lipid emulsion entraps amitriptyline in blood and may lower its brain concentration in pigs

2013 ◽  
Vol 30 ◽  
pp. 3-3
Author(s):  
J. Heinonen ◽  
E. Litonius ◽  
J. T. Backman ◽  
P. J. Neuvonen ◽  
P. H. Rosenberg
Keyword(s):  
Lipid Emulsion ◽  
Brain Concentration ◽  
Intravenous Lipid Emulsion

scholarly journals Resolution of Severe Neurologic Signs Following Intravenous Lipid Emulsion Therapy in a Young Dog With a Portosystemic Shunt: Case Report

2021 ◽  
Vol 8 ◽  
Author(s):  
Amanda M. Spillane ◽  
Jenica L. Haraschak ◽  
Maureen A. McMichael
Keyword(s):  
Hepatic Encephalopathy ◽  
Lipid Emulsion ◽  
Reference Interval ◽  
Ammonia Concentration ◽  
Acute Onset ◽  
Portosystemic Shunt ◽  
Dramatic Improvement ◽  
Intravenous Lipid Emulsion ◽  
Life Threatening ◽  
Patient’S History

A 5-month-old male intact Great Pyrenees was presented for an acute onset of severe neurologic signs (stupor, absent menace, intermittent head turn to the left). The patient's history included possible naproxen ingestion with a maximum ingested dose of 59 mg/kg, exceeding the reported dose of >50 mg/kg known to cause neurologic signs. Blood sampling for baseline bloodwork was performed, and intravenous lipid emulsion (ILE) was subsequently administered, for treatment of the suspected toxicosis. Due to severe and life-threatening neurologic signs, other methods of decontamination were contraindicated and unlikely to be effective; extracorporeal therapy was also unavailable. Complete resolution of neurologic signs occurred 30 min after completion of ILE therapy. At this time, the owners found the missing naproxen tablets after returning home and the bloodwork results returned revealing findings consistent with hepatic encephalopathy. The fasted blood ammonia concentration immediately prior to ILE administration was 702.1 μg/dL (reference interval, RI: 24–36 μg/dL) and decreased to 194.1 μg/dL 24 h later. In the first 24 h, the patient also received three doses of lactulose, N-acetylcysteine, and intravenous fluids. The patient was subsequently diagnosed with a single, large intrahepatic portosystemic shunt via computed tomography and underwent an endovascular coil embolization procedure. Given the rapid and dramatic improvement in severe neurologic signs after ILE therapy alone, it is strongly suspected that this treatment resulted in improvement of hepatic encephalopathy.

scholarly journals Intravenous Lipid Emulsion During Heart Transplantation

2021 ◽  
Author(s):  
Frederick C. Cobey ◽  
Masashi Kawabori ◽  
Roman Schumann ◽  
Gregory Couper ◽  
Iwona Bonney ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Lipid Emulsion ◽  
Intravenous Lipid Emulsion

Management of severe bupropion poisoning with intravenous lipid emulsion

2017 ◽  
Vol 56 (1) ◽  
pp. 51-54 ◽  
Author(s):  
Neeraj Chhabra ◽  
Carol DesLauriers ◽  
Michael Wahl ◽  
Sean M. Bryant
Keyword(s):  
Lipid Emulsion ◽  
Intravenous Lipid Emulsion
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