scholarly journals Improving Amphetamine Therapeutic Selectivity:N,N-dimethyl-MTA has Dopaminergic Effects and does not Produce Aortic Contraction

2013 ◽  
Vol 114 (5) ◽  
pp. 395-399 ◽  
Author(s):  
Ramón Sotomayor-Zárate ◽  
Pablo Jara ◽  
Patricio Araos ◽  
Raúl Vinet ◽  
Gabriel Quiroz ◽  
...  
Keyword(s):  
Aortic Contraction

Lack of Sumatriptan-Induced Aortic Contraction or Relaxation: 5-HT 1B Receptor Protein Detected in Endothelium and Smooth Muscle of Vasa Vasorum but Not Aorta

2002 ◽  
Vol 8 (2) ◽  
pp. 71-78 ◽  
Author(s):  
Marlene L. Cohen ◽  
Elizabeth J. Galbreath ◽  
Kathryn W. Schenck ◽  
Danqing Li ◽  
Beth J. Hoffman ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vasa Vasorum ◽  
Receptor Protein ◽  
Aortic Contraction

Degranulation enhances release of a stable contractile factor from rabbit polymorphonuclear leukocytes

1998 ◽  
Vol 274 (5) ◽  
pp. H1545-H1551
Author(s):  
Justin R. Hamilton ◽  
Joanne L. Hart ◽  
Owen L. Woodman
Keyword(s):  
Slow Rate ◽  
Polymorphonuclear Leukocytes ◽  
Cytochalasin B ◽  
Contractile Activity ◽  
90 C 10 ◽  
Isolated Aorta ◽  
Aortic Contraction ◽  
Factor Release

We investigated the release of a stable contractile factor(s) from rabbit isolated polymorphonuclear leukocytes (PMNs; 108cells/ml) incubated in Tyrode buffer at 37°C. PMNs were untreated, stimulated with N-formylmethionyl-leucyl-phenylalanine (FMLP; 0.1 μM), or degranulated with cytochalasin B (1 μM) in combination with FMLP (0.1 μM). Products from unstimulated PMNs incubated for 60 min caused significantly greater contraction of rabbit isolated aorta (0.56 ± 0.12 g, n = 8) than did products released from PMNs during a 5-min incubation (0.32 ± 0.07 g, n = 11, P < 0.05). Stimulation alone did not affect contractile factor release; however, products released from degranulated PMNs caused significantly greater aortic contraction (0.48 ± 0.08 g, n = 5) than products from nondegranulated PMNs (0.24 ± 0.04 g, n = 5, P < 0.05) after a 5-min incubation. The contractile activity of PMN-derived products was virtually abolished by heat (90°C, 10 min) or protease (trypsin; 166 U/ml, 5 h) treatment. These findings suggest a PMN-derived protein vasoconstrictor(s) is spontaneously released at a slow rate in vitro and that degranulation can enhance this rate of release. Because PMN degranulation in vivo is associated with inflammation, these results support suggestions that PMN-derived contractile factors may contribute to the impaired blood flow observed during postischemic reperfusion.

Insulin Attenuates α-adrenergic Aortic Contraction in Normotensive But not Borderline Hypertensive Rats

1995 ◽  
Vol 17 (5) ◽  
pp. 787-801 ◽  
Author(s):  
Allison P. Winecoff ◽  
Randall L. Tackett ◽  
Leslie C. Fuchs
Keyword(s):  
Hypertensive Rats ◽  
Aortic Contraction

Lack of Sumatriptan-Induced Aortic Contraction or Relaxation: 5-HT 1B Receptor Protein Detected in Endothelium and Smooth Muscle of Vasa Vasorum but Not Aorta

2002 ◽  
Vol 8 (2) ◽  
pp. 71-78
Author(s):  
Beth J. Hoffman ◽  
Anindya Bhattacharya ◽  
Marlene L. Cohen ◽  
Elizabeth J. Galbreath ◽  
Kathryn W. Schenck ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vasa Vasorum ◽  
Receptor Protein ◽  
Aortic Contraction

scholarly journals Data on the mechanisms underlying succinate-induced aortic contraction

Data in Brief ◽  
2016 ◽  
Vol 9 ◽  
pp. 206-212
Author(s):  
Natália A. Gonzaga ◽  
Janaina A. Simplicio ◽  
Letícia N. Leite ◽  
Gabriel T. Vale ◽  
José M. Carballido ◽  
...  
Keyword(s):  
Aortic Contraction

scholarly journals High-Glucose Enhances a Thromboxane A2-Induced Aortic Contraction Mediated by an Alteration of Phosphatidylinositol Turnover

2003 ◽  
Vol 92 (3) ◽  
pp. 267-282 ◽  
Author(s):  
Koji Nobe ◽  
Hikaru Suzuki ◽  
Hiromi Nobe ◽  
Yasushi Sakai ◽  
Kazutaka Momose
Keyword(s):  
High Glucose ◽  
Thromboxane A2 ◽  
Phosphatidylinositol Turnover ◽  
Aortic Contraction

Gallic acid attenuates pulmonary fibrosis in a mouse model of transverse aortic contraction-induced heart failure

2017 ◽  
Vol 99 ◽  
pp. 74-82 ◽  
Author(s):  
Li Jin ◽  
Zhe Hao Piao ◽  
Simei Sun ◽  
Bin Liu ◽  
Yuhee Ryu ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Fibrosis ◽  
Mouse Model ◽  
Gallic Acid ◽  
Aortic Contraction
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