scholarly journals Discontinuities and disruptions in drug dosage guidelines for the paediatric population

2018 ◽  
Vol 84 (5) ◽  
pp. 1029-1037
Author(s):  
Kate M. Chitty ◽  
Bosco Chan ◽  
Camille L. Pulanco ◽  
Sonya Luu ◽  
Oluwaseun Egunsola ◽  
...  
Keyword(s):  
Paediatric Population ◽  
Drug Dosage ◽  
Dosage Guidelines

Neonatology and neonatal drug dosage guidelines

1996 ◽  
pp. 267-352
Author(s):  
Susan Albersheim ◽  
Emily Ling ◽  
A. Antrim ◽  
Z. Cieslak ◽  
J. Eason ◽  
...  
Keyword(s):  
Drug Dosage ◽  
Dosage Guidelines

scholarly journals How to Modify Drug Release in Paediatric Dosage Forms? Novel Technologies and Modern Approaches with Regard to Children’s Population

2019 ◽  
Vol 20 (13) ◽  
pp. 3200 ◽  
Author(s):  
Monika Trofimiuk ◽  
Katarzyna Wasilewska ◽  
Katarzyna Winnicka
Keyword(s):  
Drug Release ◽  
Paediatric Population ◽  
Drug Dosage ◽  
Dosage Forms ◽  
Oral Dosage ◽  
Modified Release ◽  
Novel Technologies ◽  
Off Label ◽  
Pharmaceutical Technology ◽  
Oral Dosage Forms

In the pharmaceutical technology, paediatric population still presents the greatest challenge in terms of developing flexible and appropriate drug dosage forms. As for many medicines, there is a lack of paediatric dosage forms adequate for a child’s age; it is a prevailing practice to use off label formulations. Children need balanced and personalized treatment, patient-friendly preparations, as well as therapy that facilitates dosing and thus eliminates frequent drug administration, which can be ensured by modified release (MR) forms. MR formulations are commonly used in adult therapy, while rarely available for children. The aim of this article is to elucidate how to modify drug release in paediatric oral dosage forms, discuss the already accessible technologies and to introduce novel approaches of manufacturing with regard to paediatric population.

Hypercalcaemia and osteonecrosis of the jaw in association with denosumab use in the paediatric population

2019 ◽  
Author(s):  
Christie-Lee Wall ◽  
Verity Pacey ◽  
Kelly Gray ◽  
Richard McGee ◽  
Melissa Fiscaletti ◽  
...  
Keyword(s):  
Paediatric Population ◽  
Osteonecrosis Of The Jaw

Vitamin D overdose: Poor dosage guidelines for babies?

2015 ◽  
Author(s):  
Daniela Peeva ◽  
Benjamin Jacobs
Keyword(s):  
Vitamin D ◽  
Dosage Guidelines
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