scholarly journals Drug disposition and modelling before and after gastric bypass: immediate and controlled-release metoprolol formulations

2015 ◽  
Vol 80 (5) ◽  
pp. 1021-1030 ◽  
Author(s):  
Ina Gesquiere ◽  
Adam S. Darwich ◽  
Bart Van der Schueren ◽  
Jan de Hoon ◽  
Matthias Lannoo ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Controlled Release ◽  
Drug Disposition ◽  
Before And After

scholarly journals Drug disposition before and after gastric bypass: fenofibrate and posaconazole

2016 ◽  
Vol 82 (5) ◽  
pp. 1325-1332 ◽  
Author(s):  
Ina Gesquiere ◽  
Bart Hens ◽  
Bart Van der Schueren ◽  
Raf Mols ◽  
Jan de Hoon ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Drug Disposition ◽  
Before And After

GLP-1, insulin and glucose levels during mixed test meal before and after gastric bypass surgery in obese patients

2014 ◽  
Author(s):  
Dragan Micic ◽  
Snezana Polovina ◽  
Danka Jeremic ◽  
Dusan Micic ◽  
Mirjana Sumarac-Dumanovic
Keyword(s):  
Gastric Bypass ◽  
Test Meal ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Obese Patients ◽  
Glucose Levels ◽  
Before And After

Controlled Release of Protein from Hydrocolloid Gel Microbeads Before and After Drying

2004 ◽  
Vol 1 (3) ◽  
pp. 265-273 ◽  
Author(s):  
R. Mukai-Correa ◽  
A. Prata ◽  
I. Alvim ◽  
C. Grosso
Keyword(s):  
Controlled Release ◽  
Before And After

scholarly journals Orosensory Perception of Fat/Sweet Stimuli and Appetite-Regulating Peptides before and after Sleeve Gastrectomy or Gastric Bypass in Adult Women with Obesity

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 878
Author(s):  
Arnaud Bernard ◽  
Johanne Le Beyec-Le Bihan ◽  
Loredana Radoi ◽  
Muriel Coupaye ◽  
Ouidad Sami ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Gut Hormones ◽  
Sweet Taste ◽  
Taste Perception ◽  
Taste Sensitivity ◽  
Adult Women ◽  
Before And After ◽  
The Impact

The aim of this study was to explore the impact of bariatric surgery on fat and sweet taste perceptions and to determine the possible correlations with gut appetite-regulating peptides and subjective food sensations. Women suffering from severe obesity (BMI > 35 kg/m2) were studied 2 weeks before and 6 months after a vertical sleeve gastrectomy (VSG, n = 32) or a Roux-en-Y gastric bypass (RYGB, n = 12). Linoleic acid (LA) and sucrose perception thresholds were determined using the three-alternative forced-choice procedure, gut hormones were assayed before and after a test meal and subjective changes in oral food sensations were self-reported using a standardized questionnaire. Despite a global positive effect of both surgeries on the reported gustatory sensations, a change in the taste sensitivity was only found after RYGB for LA. However, the fat and sweet taste perceptions were not homogenous between patients who underwent the same surgery procedure, suggesting the existence of two subgroups: patients with and without taste improvement. These gustatory changes were not correlated to the surgery-mediated modifications of the main gut appetite-regulating hormones. Collectively these data highlight the complexity of relationships between bariatric surgery and taste sensitivity and suggest that VSG and RYGB might impact the fatty taste perception differently.

Energy Expenditure Before and After Roux-en-Y Gastric Bypass

2012 ◽  
Vol 22 (9) ◽  
pp. 1450-1455 ◽  
Author(s):  
Silvia Leite Faria ◽  
Orlando Pereira Faria ◽  
Cynthia Buffington ◽  
Mariane de Almeida Cardeal ◽  
Heloisa Rodrigues de Gouvêa
Keyword(s):  
Gastric Bypass ◽  
Energy Expenditure ◽  
Before And After

scholarly journals MP012PROBABILITY OF RENAL STONE FORMATION (PSF) IN OBESE PATIENTS BEFORE AND AFTER GASTRIC BYPASS SURGERY; APPLICABILITY OF A PREVENTIVE STRATEGY

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii432-iii432
Author(s):  
Thomas Ernandez ◽  
Catherine Stoermann-Chopard ◽  
Minoa Jung ◽  
William Robertson ◽  
Pierre-Yves Martin ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Bypass Surgery ◽  
Renal Stone ◽  
Stone Formation ◽  
Gastric Bypass Surgery ◽  
Preventive Strategy ◽  
Obese Patients ◽  
Before And After

Thyroid function before and after Roux-en-Y gastric bypass: an observational study

2020 ◽  
Vol 16 (2) ◽  
pp. 261-269
Author(s):  
Paula Carolina Dambros Granzotto ◽  
Cleo Otaviano Mesa Junior ◽  
Rodrigo Strobel ◽  
Rosana Radominski ◽  
Hans Graf ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Observational Study ◽  
Thyroid Function ◽  
Before And After

scholarly journals Investigating Intestinal Glucagon After Roux-en-Y Gastric Bypass Surgery

2019 ◽  
Vol 104 (12) ◽  
pp. 6403-6416 ◽  
Author(s):  
Tina Jorsal ◽  
Nicolai J Wewer Albrechtsen ◽  
Marie M Christensen ◽  
Brynjulf Mortensen ◽  
Erik Wandall ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Small Intestine ◽  
Gastric Bypass Surgery ◽  
Plasma Concentrations ◽  
University Hospital ◽  
Morbidly Obese ◽  
Mucosal Biopsy ◽  
Cross Sectional ◽  
Biopsy Specimens ◽  
Before And After

Abstract Context After Roux-en-Y gastric bypass (RYGB) surgery, postprandial plasma glucagon concentrations have been reported to increase. This occurs despite concomitant improved glucose tolerance and increased circulating plasma concentrations of insulin and the glucagon-inhibiting hormone glucagon-like peptide 1 (GLP-1). Objective To investigate whether RYGB-induced hyperglucagonemia may be derived from the gut. Design and Setting Substudy of a prospective cross-sectional study at a university hospital in Copenhagen, Denmark. Participants Morbidly obese individuals undergoing RYGB (n = 8) with or without type 2 diabetes. Interventions Three months before and after RYGB, participants underwent upper enteroscopy with retrieval of gastrointestinal mucosal biopsy specimens. Mixed-meal tests were performed 1 week and 3 months before and after RYGB. Main Outcome Measures The 29–amino acid glucagon concentrations in plasma and in mucosal gastrointestinal biopsy specimens were assessed using mass spectrometry–validated immunoassays, and a new monoclonal antibody reacting with immunoreactive glucagon was used for immunohistochemistry. Results Postprandial plasma concentrations of glucagon after RYGB were increased. Expression of the glucagon gene in the small intestine increased after surgery. Glucagon was identified in the small-intestine biopsy specimens obtained after, but not before, RYGB. Immunohistochemically, mucosal biopsy specimens from the small intestine harbored cells costained for GLP-1 and immunoreactive glucagon. Conclusion Increased concentrations of glucagon were observed in small-intestine biopsy specimens and postprandially in plasma after RYGB. The small intestine harbored cells immunohistochemically costaining for GLP-1 and glucagon-like immunoreactivity after RYGB. Glucagon derived from small-intestine enteroendocrine l cells may contribute to postprandial plasma concentrations of glucagon after RYGB.

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