Safety and immunogenicity of a novel cold-adapted modified-live equine influenza virus vaccine

2014 ◽  
Vol 92 (11) ◽  
pp. 450-457 ◽  
Author(s):  
K Tabynov ◽  
Z Kydyrbayev ◽  
S Ryskeldinova ◽  
N Assanzhanova ◽  
Y Kozhamkulov ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Virus Vaccine ◽  
Influenza Virus Vaccine ◽  
Equine Influenza Virus ◽  
Cold Adapted ◽  
Equine Influenza

Antigenic differences between equine influenza virus vaccine strains and Florida sublineage clade 1 strains isolated in Europe in 2019

2021 ◽  
Vol 272 ◽  
pp. 105674
Author(s):  
Manabu Nemoto ◽  
Minoru Ohta ◽  
Takashi Yamanaka ◽  
Yoshinori Kambayashi ◽  
Hiroshi Bannai ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Virus Vaccine ◽  
Influenza Virus Vaccine ◽  
Equine Influenza Virus ◽  
Equine Influenza ◽  
Clade 1

Formulation with CpG ODN enhances antibody responses to an equine influenza virus vaccine

2006 ◽  
Vol 114 (1-2) ◽  
pp. 103-110 ◽  
Author(s):  
A.M. Lopez ◽  
R. Hecker ◽  
G. Mutwiri ◽  
S. van Drunen Littel-van den Hurk ◽  
L.A. Babiuk ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Virus Vaccine ◽  
Influenza Virus Vaccine ◽  
Antibody Responses ◽  
Cpg Odn ◽  
Equine Influenza Virus ◽  
Equine Influenza

scholarly journals Protection against the New Equine Influenza Virus Florida Clade I Outbreak Strain Provided by a Whole Inactivated Virus Vaccine

Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 784
Author(s):  
Sylvia Reemers ◽  
Sander van Bommel ◽  
Qi Cao ◽  
David Sutton ◽  
Saskia van de Zande
Keyword(s):  
Influenza Virus ◽  
Virus Vaccine ◽  
Clinical Signs ◽  
Field Strain ◽  
Equine Influenza Virus ◽  
Outbreak Strain ◽  
Virus Shedding ◽  
Equine Influenza ◽  
Vaccine Type ◽  
High Level

Equine influenza virus (EIV) is a major cause of respiratory disease in horses. Vaccination is an effective tool for infection control. Although various EIV vaccines are widely available, major outbreaks occurred in Europe in 2018 involving a new EIV H3N8 FC1 strain. In France, it was reported that both unvaccinated and vaccinated horses were affected despite >80% vaccination coverage and most horses being vaccinated with a vaccine expressing FC1 antigen. This study assessed whether vaccine type, next to antigenic difference between vaccine and field strain, plays a role. Horses were vaccinated with an ISCOMatrix-adjuvanted, whole inactivated virus vaccine (Equilis Prequenza) and experimentally infected with the new FC1 outbreak strain. Serology (HI), clinical signs, and virus shedding were evaluated in vaccinated compared to unvaccinated horses. Results showed a significant reduction in clinical signs and a lack of virus shedding in vaccinated horses compared to unvaccinated controls. From these results, it can be concluded that Equilis Prequenza provides a high level of protection to challenge with the new FC1 outbreak strain. This suggests that, apart from antigenic differences between vaccine and field strain, other aspects of the vaccine may also play an important role in determining field efficacy.

scholarly journals Immunogenicity and Protective Efficacy of Seasonal Human Live Attenuated Cold-Adapted Influenza Virus Vaccine in Pigs

2019 ◽  
Vol 10 ◽  
Author(s):  
Barbara Holzer ◽  
Sophie B. Morgan ◽  
Veronica Martini ◽  
Rajni Sharma ◽  
Becky Clark ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Virus Vaccine ◽  
Protective Efficacy ◽  
Influenza Virus Vaccine ◽  
Cold Adapted
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