Efficacy of a buccal meloxicam formulation for pain relief in Merino lambs undergoing knife castration and tail docking in a randomised field trial

AH Small; S Belson; M Holm; IG Colditz

doi:10.1111/avj.12241

Efficacy of a buccal meloxicam formulation for pain relief in Merino lambs undergoing knife castration and tail docking in a randomised field trial

Australian Veterinary Journal ◽

10.1111/avj.12241 ◽

2014 ◽

Vol 92 (10) ◽

pp. 381-388 ◽

Cited By ~ 22

Author(s):

AH Small ◽

S Belson ◽

M Holm ◽

IG Colditz

Keyword(s):

Pain Relief ◽

Field Trial ◽

Tail Docking

Download Full-text

Three Studies Evaluating the Potential for Lidocaine, Bupivacaine or Procaine to Reduce Pain-Related Behaviors following Ring Castration and/or Tail Docking in Lambs

Animals ◽

10.3390/ani11123583 ◽

2021 ◽

Vol 11 (12) ◽

pp. 3583

Author(s):

Alison Small ◽

Manon Fetiveau ◽

Robin Smith ◽

Ian Colditz

Keyword(s):

Pain Relief ◽

Local Anesthesia ◽

Acute Pain ◽

Local Anesthetics ◽

Behavioral Responses ◽

Pain Behavior ◽

Duration Of Action ◽

Duration Of Effect ◽

Post Procedure ◽

Tail Docking

The use of local anesthesia at the time of ring castration and tail docking can improve lamb welfare. However, few local anesthetics are registered for sheep, and data on their duration of effect is limited. Three studies were conducted to evaluate the efficacy of procaine (P), lidocaine (L), and bupivacaine (B) in terms of observed alleviation of behavioral responses to castration and/or tail docking in 10-min blocks in the first 60 min post-treatment. In each study, comparisons were made between two groups of lambs castrated and/or tail docked with rubber rings and either receiving the agent using the NUMNUTS® instrument (N) or receiving no anesthetic agent (RR). Acute pain behavior was lower in NL (n = 28) than RRL (n = 15) males in the first 10 min post-procedure (p < 0.05); lower in NB (n = 16) than RRB (n = 16) males in periods 10–20 min (0.05 < p < 0.01), 20–30 min (p < 0.05) and 40–50 min (0.05 < p < 0.01); lower in NB (n = 16) than RRB (n = 16) females between 20 and 40 min post-procedure (0.05 < p < 0.01); lower in NP (n = 8) than RRP (n = 7) males in period 10–20 min (0.05 < p < 0.01), and lower in NP (n = 9) than RRP (n = 9) females in periods 0–10 min (0.05 < p < 0.01), and 10–40 min (p < 0.05). Benefits were modest, and the effects of procaine appear to last longer than lidocaine, while bupivacaine is slower to take effect than either procaine or lidocaine but may provide longer-lasting pain relief. The duration of action of local anesthetics is short in sheep, and detailed behavioral evaluations are required in the first hour post-procedure to establish efficacy.

Download Full-text

Electro-analgesia for sheep husbandry practices: a review

Animal Production Science ◽

10.1071/an15195 ◽

2017 ◽

Vol 57 (5) ◽

pp. 801

Author(s):

P. I. Hynd

Keyword(s):

Pain Relief ◽

High Frequency ◽

Electrical Current ◽

Very High Frequency ◽

Electrical Nerve Stimulation ◽

Tail Docking ◽

Husbandry Practices ◽

The Brain ◽

Very High ◽

A Current

Several sheep-husbandry practices such as mulesing, castration, ear-tagging and tail-docking are currently performed with no, or little, anaesthesia or analgesia. The potential for using electrotherapies to provide analgesia during and after these operations is examined in this review. The most common electrotherapy is transcutaneous electrical nerve stimulation (TENS). TENS is the application of an electrical current from electrodes placed on the skin. Analysis of a large number of trials in humans and in animal models indicates that TENS provides effective relief from acute and chronic pain, including pain associated with surgery. There is strong evidence now that TENS analgesia operates at the levels of the periphery, the spinal cord and in the brain. The mechanisms involve the autonomic nervous system, the opioid pathways and neurotransmitters involved in descending inhibitory pathways from the brain. Centrally operating pathways mean the current does not have to be applied near the injured site and there is evidence of sustained pain relief lasting hours, days or even weeks post-treatment, particularly after very high-frequency, randomly variable current applications. Treatment of sheep during painful operations with such a current has the potential to provide immediate and possibly sustained pain relief. Combining such a treatment with electro-immobilisation of the animal would be advantageous for sheep-husbandry operations, but there is considerable evidence that high-intensity currents producing tetanic contractions are aversive and probably painful for sheep. Investigations of the application and efficacy of electrotherapies for painful sheep operations should be undertaken.

Download Full-text