Immune response during the onset of coliform mastitis in dairy cows vaccinated with STARTVAC ®

2021 ◽  
Vol 92 (1) ◽  
Author(s):  
Kazuhiro Kawai ◽  
Yasuha Kondo ◽  
Yasunori Shinozuka ◽  
Ryusaku Kawata ◽  
Sohei Kaneko ◽  
...  
Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1858
Author(s):  
Karen Wagener ◽  
Marc Drillich ◽  
Christine Aurich ◽  
Christoph Gabler

Our objective was to investigate the level of endometrial immune response at artificial insemination (AI) and to relate it to subsequent fertility. From 71 healthy cows, endometrial cytobrush samples were taken at the first AI for cytological and mRNA analyses. Total RNA isolated from the cytobrushes was used for reverse transcription qPCR for selected transcripts. Animals were grouped into pregnant (PREG; n = 32) and non-pregnant (non-PREG; n = 39) cows following their first AI. The mRNA abundance of the neutrophil-related factor CEACAM1 and the chemokine CXCL5 was 1.2- (p = 0.03) and 2.0-fold (p = 0.04) greater in PREG than in non-PREG cows, respectively. Animals were further subdivided according to the number of inseminations until pregnancy (PREG1, n = 32; PREG2-3, n = 19) and in repeat breeder cows (RBC, n = 13). CEACAM1 and CXCL8 mRNA expression was 1.7- (p = 0.01) and 2.3-fold (p = 0.03) greater in PREG1 than in RBC, respectively. Cox regression showed that cows with PMN ≥ 1% had a 1.8-fold increased chance of pregnancy within 150 days postpartum compared with cows with fewer PMNs. We conclude that a certain level of inflammation before the stimulus of AI might be beneficial for subsequent fertility.


2020 ◽  
Vol 82 (4) ◽  
pp. 457-462 ◽  
Author(s):  
Keiichi HISAEDA ◽  
Tomoko KOSHIISHI ◽  
Ayuna SASAKI ◽  
Yasunori SHINOZUKA ◽  
Naoki ISOBE ◽  
...  

2014 ◽  
Vol 97 (12) ◽  
pp. 7426-7436 ◽  
Author(s):  
I.M.T. Thompson ◽  
S. Tao ◽  
A.P.A. Monteiro ◽  
K.C. Jeong ◽  
G.E. Dahl

Reproduction ◽  
1971 ◽  
Vol 25 (2) ◽  
pp. 193-199 ◽  
Author(s):  
J. F. T. GRIFFIN ◽  
W. R. NUNN ◽  
P. J. HARTIGAN
Keyword(s):  

2016 ◽  
Vol 1 (4) ◽  
Author(s):  
Matthew Barden

Clinical bottom line In spite of limitations to the available studies, in cattle with clinical mastitis and an absence of systemic signs there is no evidence that combined systemic and intramammary antimicrobial therapy improves clinical cure rates compared to intramammary antimicrobial therapy only. In two studies, cattle with severe coliform mastitis showed improved clinical parameters following combined systemic and intramammary antimicrobial therapy compared to intramammary antimicrobial therapy only. 


2016 ◽  
Vol 146 ◽  
pp. 99-108 ◽  
Author(s):  
Li Min ◽  
Jianbo Cheng ◽  
Shengguo Zhao ◽  
He Tian ◽  
Yangdong Zhang ◽  
...  

2009 ◽  
Vol 10 (1) ◽  
pp. 21-38 ◽  
Author(s):  
Manuela Rinaldi ◽  
Robert W. Li ◽  
Douglas D. Bannerman ◽  
Kristy M. Daniels ◽  
Christina Evock-Clover ◽  
...  

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