Effect of candidate gene polymorphisms on reproductive traits in a Large White pig population

2016 ◽  
Vol 87 (12) ◽  
pp. 1455-1463 ◽  
Author(s):  
Shuji Sato ◽  
Takashi Kikuchi ◽  
Yoshinobu Uemoto ◽  
Satoshi Mikawa ◽  
Keiichi Suzuki
Keyword(s):  
Candidate Gene ◽  
Gene Polymorphisms ◽  
Reproductive Traits ◽  
Large White ◽  
Large White Pig

scholarly journals 7. Associations between Polymorphisms in the DIO3 Gene and Reproductive Traits and Carcass Performance in Pigs

2016 ◽  
Vol 16 (2) ◽  
pp. 399-413
Author(s):  
Maria Oczkowicz ◽  
Anna Dunkowska ◽  
Katarzyna Piórkowska ◽  
Aurelia Mucha ◽  
Mirosław Tyra ◽  
...  
Keyword(s):  
Association Study ◽  
Candidate Gene ◽  
Carcass Traits ◽  
Reproductive Traits ◽  
Large White ◽  
The Third ◽  
Large White Breed ◽  
Population Average ◽  
White Breed ◽  
Carcass Performance

Abstract Recently, DIO3 gene has been proposed as a candidate gene for litter size in pigs. Moreover, it was shown that polymorphism in this gene is associated with carcass traits. In this study we identified several SNPs within coding sequence of DIO3 by HRM method and performed association study between two polymorphisms and reproductive and carcass traits in pigs bred in Poland. Analysis of 350 pigs of Landrace and Large White breed revealed several significant associations for rs80999359, like period between the second and third parities (2IP)(P<0.0008) in the whole population, period between the third and fourth parities (3IP) (P<0.022), number of piglets born alive (L3NBA) (P<0.0084) and number of piglets at 21 days (L3NB21d) (P<0.0176) at the third parity in Large White as well as period between the second and third parities (2IP) (P<0.0012) in Landrace breed. The second polymorphism (rs80983654) was associated with 1IP (P<0.0218), number of piglets born alive at the fourth parity (L4NBA, P<0.027), number of piglets at 21 day at the fourth litter (L4NB21d, P<0.01), in the whole population, average number of piglets born alive (ANBA, P<0.01250), average number of piglets at 21 day (ANB21d, P<0.009), average interparity period (AIP, P<0.016), age at the first parity (1AP, P<0.003), (1IP, P<0.001, L4NBA, P<0.017, L4NB21d, P<0.005) in Large White breed. In contrast, we have found only few associations between DIO3 polymorphisms and carcass traits. rs80999359 was associated with backfat thickness (p<0.01) while rs80983654 with the weight of ham. Our results suggest that polymorphisms within DIO3 gene may be associated with reproductive traits.

scholarly journals Variants in BMP7 and BMP15 3’-UTRs Associated with Reproductive Traits in a Large White Pig Population

Animals ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 905 ◽  
Author(s):  
Yin ◽  
Du ◽  
Li ◽  
Pan ◽  
Wu ◽  
...  
Keyword(s):  
Point Mutations ◽  
Reproductive Traits ◽  
Regulatory Elements ◽  
Large White ◽  
Morphogenetic Protein ◽  
Pooled Dna ◽  
Trait Locus ◽  
Whole Genome Resequencing ◽  
Weight Trait ◽  
Large White Pig

Bone morphogenetic protein 7 (BMP7) and BMP15, which encode members of the BMP family, have been identified by whole-genome resequencing as breeding-related genes that overlap with a known quantitative trait locus for reproductive traits. In this study, we investigated the effects of variants at the BMP7 and BMP15 gene loci on sow reproductive traits. We isolated 669 and 1213 bp sequences of the 3’-untranslated region (3’-UTR) of the porcine BMP7 and BMP15 genes, respectively, and detected several RNA regulatory elements, such as miRNA response elements and AU-rich elements. Pooled DNA sequencing identified two novel point mutations (viz., BMP7 c.1569A>G and BMP15 c.2366G>A) in the 3’-UTR. Association analysis showed that the c.1569A>G polymorphism was associated with the litter weight trait in a Large White pig population. Furthermore, analysis of the combined genetic effects revealed that AA/GA and AG/GG were the favorable combined genotypes for the total number of piglets born (TNB) and the total number of piglets born alive (NBA), whereas. Together, our findings confirm that BMP7 and BMP15 are candidate genes for porcine reproductive performance.

scholarly journals Genome-wide association study for reproductive traits in a Large White pig population

2018 ◽  
Vol 49 (2) ◽  
pp. 127-131 ◽  
Author(s):  
Y. Wang ◽  
X. Ding ◽  
Z. Tan ◽  
K. Xing ◽  
T. Yang ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Large White ◽  
Genome Wide ◽  
Large White Pig

scholarly journals Effects of KPNA7 gene polymorphisms on reproductive traits in France Large White pigs

2021 ◽  
Vol 49 (1) ◽  
pp. 352-356
Author(s):  
Yunxia Zhang ◽  
Mingyang Li ◽  
Jun Liu ◽  
Yaxin Peng ◽  
Bo Zuo ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Reproductive Traits ◽  
Large White

Associations of QTL Region Genes of Chromosome 2 with Meat Quality Traits and Productivity of the Ukrainian Large White Pig Breed

2021 ◽  
Vol 55 (1) ◽  
pp. 53-62
Author(s):  
V. N. Balatsky ◽  
Y. K. Oliinychenko ◽  
T. V. Buslyk ◽  
I. B. Bankovska ◽  
S. N. Korinnyi ◽  
...  
Keyword(s):  
Meat Quality ◽  
Quality Traits ◽  
Chromosome 2 ◽  
Large White ◽  
Meat Quality Traits ◽  
Large White Pig
Sign in / Sign up

Export Citation Format

Share Document