Novel operative approach to double primary cancers of the breast and thyroid and its effects on cosmesis and the accuracy of follow-up examinations

2018 ◽  
Vol 11 (2) ◽  
pp. 185-188
Author(s):  
Masayuki Tori ◽  
Toshirou Shimo ◽  
Katsuhide Yoshidome
Keyword(s):  
Operative Approach ◽  
Double Primary Cancers

scholarly journals Incarcerated Femoral Hernia Repair with Ventralex™ Hernia Patch through Same Skin Incision and Suprainguinal Laparotomy

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
David Aranovich ◽  
Veacheslav Zilbermints ◽  
Oleg Kaminsky
Keyword(s):  
Hernia Repair ◽  
Femoral Hernia ◽  
Bowel Resection ◽  
Abdominal Cavity ◽  
Skin Incision ◽  
Operative Approach ◽  
Easy Access ◽  
Midline Laparotomy ◽  
Femoral Ring

Purpose. To report our experience with incarcerated femoral hernia procedure, which allows laparotomy through same inguinal skin incision, inspection and resection of compromised bowel, and preperitoneal tension-free transabdominal repair with Ventralex™ Hernia Patch.Materials and Methods. The suprainguinal laparotomy was performed via same groin incision without compromising iliopubic tract. The femoral ring was sealed with Ventralex™ Hernia Patch pulled through the abdominal cavity and secured outside. Five consecutive patients diagnosed with incarcerated femoral hernias were operated. All of them required laparotomy, either for bowel resection (n=3) or for inspection of viability (n=2).Results. All patients tolerated the procedure well. There were no wound or mesh infections, incisional hernias, or recurrences during follow-up.Conclusions. Our easy-to-master operative approach to incarcerated femoral hernia allows easy access to abdominal cavity through same groin incision without compromising iliopubic tract or midline laparotomy. Reduction of incarcerated bowel and its inspection and resection can be safely performed. The femoral ring defect can be effectively obliterated with Ventralex™ Hernia Patch.

Arteriovenous malformation in the basal ganglia

1974 ◽  
Vol 41 (2) ◽  
pp. 244-247
Author(s):  
Ivan I. Ribaric
Keyword(s):  
Surgical Treatment ◽  
Basal Ganglia ◽  
Arteriovenous Malformation ◽  
Operative Approach ◽  
Content Type ◽  
Fine Print

✓ The author reports the successful surgical treatment of an arteriovenous malformation of the basal ganglia. Follow-up angiography verified that the single supplying artery had been clipped. The operative approach to the malformation is discussed.

Risk of recurrence in patients with positive surgical margin at apex only versus other locations after radical prostatectomy.

2019 ◽  
Vol 37 (7_suppl) ◽  
pp. 124-124
Author(s):  
Masashi Kato ◽  
Akiyuki Yamamoto ◽  
Ryo Ishida ◽  
Tohru Kimura ◽  
Tomoyasu Sano ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Adjuvant Therapy ◽  
Surgical Margin ◽  
Operative Approach ◽  
Positive Surgical Margin ◽  
Grade Group ◽  
Clinical Recurrence ◽  
Prostate Cancer Death

124 Background: Some reported that positive surgical margin at radical prostatectomy (RP) was a prognostic factor of clinical recurrence and prostate cancer death, and others showed that was not necessarily true. The prostatic apex is most popular location of positive surgical margin at RP and the frequency of apex is reported to be about 20-40% of all positive cases. Prostatic apex is also reported to lack a well-defined capsule and to be hardly retracted during operation. In this study, we evaluated the effect of positive surgical margin at apex-only on prognosis after RP in a large cohort. Methods: We retrospectively evaluated 1019 patients with prostate cancer who underwent radical prostatectomy without neoadjuvant or adjuvant therapy at the hospitals that the authors were affiliated with between 2005 and 2013. The operative approach (open, laparoscopic, or robotic) was decided by each institution. All prostatectomy specimen slides were reviewed by a single genitourinary pathologist according to ISUP 2014 criteria. Recurrence following RP was defined according to AUA guidelines. Results: The median patient age was 67 (range, 45–80) years. The median initial PSA was 6.8 ng/ml (range, 0.4–82 ng/ml). The median follow-up period was 69 (range, 0.7–135) months. Pathological T stage was in 72.5% of pT2 (n = 739), 23.4% of pT3a (n = 238), and 4.1% of pT3b (n = 42). There were 163 Grade Group (GG) 1 cases, 502 GG 2, 217 GG 3, 39 GG 4, and 98 GG 5 cases. 372 cases had positive surgical margin. Details were 201 (54%) apex only, 57 (15%) anterior, 43 (12%) posterior, 76 (20%) lateral, 40 (11%) bladder. Some patients showed multiple positive surgical margin. The patients with positive surgical margin at apex-only showed significantly better prognosis than other locations (P = 0.0001). This result was confirmed in each operative approach (open; P = 0.008, laparoscopic; P = 0.001, robotic; P = 0.01). Conclusions: Among surgical margin positive patients after RP, those at prostatic apex-only showed lower biochemical recurrence than other locations regardless of operative approach. Physician should follow such a patient carefully without adjuvant therapy.

scholarly journals Double primary cancers registered in a tertiary care hospital: review of two cases

2014 ◽  
Vol 5 (1) ◽  
pp. 6-10
Author(s):  
Amrallah A. Mohammad ◽  
Abdullah S. Al-Zahrani ◽  
Hani M. El-Khatib
Keyword(s):  
Female Patient ◽  
Tertiary Care ◽  
Malignant Neoplasms ◽  
Care Hospital ◽  
Curative Intent ◽  
First Case ◽  
Increased Risk ◽  
Multiple Primary ◽  
Double Primary Cancers

Abstract In our centre, among 1965 registered cancer patients between May 2011 and December 2013, we report three cases with multiple primary malignant neoplasms. One of them was excluded due to lack of data, and so we present the remaining two cases. The first case is an 82-year-old female patient with colon and thyroid cancer and the second case is a 61-year-old female patient with colon and breast cancer. Both cases were metachronous and discovered accidently during the regular follow up, and managed with a curative intent. Conclusion: It is important for the clinicians to keep in mind that individuals with cancer are at increased risk for subsequent primary malignancies, which must be differentiated from recurrent or metastatic disease.

scholarly journals A Novel Anatomical Locking Plate Combined With an Anterior Column Screw and Magic Screw for Acetabular Fractures Involving Both Columns: Reduction Effect and Functional Outcomes

2020 ◽  
Author(s):  
Gongzi Zhang ◽  
Shuwei Zhang ◽  
Yi Sui ◽  
Xiang Wang ◽  
Xiuyun Su ◽  
...  
Keyword(s):  
Acetabular Fracture ◽  
Locking Plate ◽  
Operation Time ◽  
Operative Approach ◽  
Acetabular Fractures ◽  
Fracture Classification ◽  
Reduction Effect ◽  
Transverse Fractures ◽  
Time From Injury

Abstract BackgroundA novel anatomical locking plate (NALP) was designed. The NALP is fixed via an anterior column screw and a Magic screw to apply pressure on the acetabular fracture ends. This study was performed to compare the reduction effect and clinical outcome of the NALP versus the anatomical locking plate (ALP) for acetabular fractures involving both columns.MethodsFrom January 2013 to January 2018, 22 patients with acetabular fractures involving both columns were treated using the NALP or ALP in a single institution. The general condition and type of fracture were recorded. The NALP and ALP groups were compared regarding the Letournel fracture classification, operative approach, time from injury to operation, intraoperative bleeding volume, and operation time. The radiographic reduction outcome and hip function at final follow-up were compared between the two groups based on the Matta scores and Harris hip scores, respectively.ResultsThe NALP was used in 10 patients, while the ALP was used in 12. Three patients had transverse fractures, 12 had transverse fractures involving posterior wall, and 7 had double-column fractures. The two groups had no significantly differ regarding sex, age, affected side, Letournel fracture classification, operative approach, or follow-up duration. The time from injury to the operation was 20.70±1.2 days in the NALP group and 13.17±7.5 days in the ALP group (p=0.089). The operation time was 332.20±128.9 minutes in the NALP group and 257.50±91.6 minutes in the ALP group (p=0.128). The intraoperative blood loss volume was 1550.00±869.5 ml in the NALP group and 666.67±370.1 ml in the ALP group (p=0.011). The Matta score at final follow-up was 1.10±0.8 in the NALP group and 2.46±1.9 in the ALP group (p=0.045). The Harris hip score at final follow-up was 87.50±10.5 in the NALP group and 81.00±10.1 in the ALP group (p=0.0782).ConclusionThe NALP achieves adequate compression of the acetabular fracture ends and obtains stronger fixation than the ALP.Trial registrationChiCTR,ChiCTR2000030825. Registered 15 March 2020 - Retrospectively registered, http://www.chictr.org.cn/ChiCTR2000030825

Osteoplastic Frontal Sinusotomy

1976 ◽  
Vol 85 (4) ◽  
pp. 523-532 ◽  
Author(s):  
James M. Hardy ◽  
William W. Montgomery
Keyword(s):  
Postoperative Complications ◽  
Revision Surgery ◽  
Frontal Sinus ◽  
Chronic Sinusitis ◽  
Operative Approach ◽  
Indications For Surgery ◽  
Sinus Infection

The operative approach and findings of 250 osteoplastic frontal sinusotomy operations performed from 1956 through 1972 at the Massachusetts Eye and Ear Infirmary are reviewed. Indications for surgery were symptomatic and/or complicated disease of the frontal sinus, including primary chronic sinusitis and osteoma or trauma with or without associated infection. Immediate postoperative complications were minor. Follow-up of at least three years was obtained in 83% of the patients, and 93% of these have no significant symptoms to date. A distressing problem of persistent postoperative frontal pain is discussed in detail. Revision surgery has been performed in 6% of patients due to recurrent frontal sinus infection. The reasons for failure are analyzed, and recommendations are made to minimize the possibility of recurrence.

scholarly journals A Novel Anatomical Locking Plate Combined with an Anterior Column Screw and Magic Screw for Acetabular Fractures Involving Both Columns: Reduction Effect and Functional Outcomes

2020 ◽  
Author(s):  
Gongzi Zhang ◽  
Shuwei Zhang ◽  
Yi Sui ◽  
Xiang Wang ◽  
Xiuyun Su ◽  
...  
Keyword(s):  
Acetabular Fracture ◽  
Locking Plate ◽  
Operation Time ◽  
Operative Approach ◽  
Acetabular Fractures ◽  
Fracture Classification ◽  
Reduction Effect ◽  
Transverse Fractures ◽  
Time From Injury

Abstract Background: A novel anatomical locking plate (NALP) was designed. The NALP is fixed via an anterior column screw and a Magic screw to apply pressure on the acetabular fracture ends. This study was performed to compare the reduction effect and clinical outcome of the NALP versus the anatomical locking plate (ALP) for acetabular fractures involving both columns.Methods: From January 2013 to January 2018, 22 patients with acetabular fractures involving both columns were treated using the NALP or ALP in a single institution. The general condition and type of fracture were recorded. The NALP and ALP groups were compared regarding the Letournel fracture classification, operative approach, time from injury to operation, intraoperative bleeding volume, and operation time. The radiographic reduction outcome and hip function at final follow-up were compared between the two groups based on the Matta scores and Harris hip scores, respectively.Results: The NALP was used in 10 patients, while the ALP was used in 12. Three patients had transverse fractures, 12 had transverse fractures involving posterior wall, and 7 had double-column fractures. The two groups had no significantly differ regarding sex, age, affected side, Letournel fracture classification, operative approach, or follow-up duration. The time from injury to the operation was 20.70±1.2 days in the NALP group and 13.17±7.5 days in the ALP group (p=0.089). The operation time was 332.20±128.9 minutes in the NALP group and 257.50±91.6 minutes in the ALP group (p=0.128). The intraoperative blood loss volume was 1550.00±869.5 ml in the NALP group and 666.67±370.1 ml in the ALP group (p=0.011). The Matta score at final follow-up was 1.10±0.8 in the NALP group and 2.46±1.9 in the ALP group (p=0.045). The Harris hip score at final follow-up was 87.50±10.5 in the NALP group and 81.00±10.1 in the ALP group (p=0.0782).Conclusion: The NALP achieves adequate compression of the acetabular fracture ends and obtains stronger fixation than the ALP.Trial registration: ChiCTR,ChiCTR2000030825. Registered 15 March 2020 - Retrospectively registered, http://www.chictr.org.cn/ChiCTR2000030825

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

Brief summary of Kleť photographic search programme for minor planets

1999 ◽  
Vol 173 ◽  
pp. 189-192
Author(s):  
J. Tichá ◽  
M. Tichý ◽  
Z. Moravec
Keyword(s):  
Ccd Camera ◽  
Minor Planet ◽  
Minor Planets ◽  
Main Belt

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.

Intranuclear Crystals in Regenerating Canine Kidneys

1973 ◽  
Vol 31 ◽  
pp. 412-413
Author(s):  
D.G. Osborne ◽  
L.J. McCormack ◽  
M.O. Magnusson ◽  
W.S. Kiser
Keyword(s):  
Epithelial Cell ◽  
Epithelial Cells ◽  
Tubular Epithelial Cell ◽  
Tubular Epithelial Cells ◽  
Cell Nuclei ◽  
Crystalline Structures ◽  
Small Crystals ◽  
Membrane Bound

During a project in which regenerative changes were studied in autotransplanted canine kidneys, intranuclear crystals were seen in a small number of tubular epithelial cells. These crystalline structures were seen in the control specimens and also in regenerating specimens; the main differences being in size and number of them. The control specimens showed a few tubular epithelial cell nuclei almost completely occupied by large crystals that were not membrane bound. Subsequent follow-up biopsies of the same kidneys contained similar intranuclear crystals but of a much smaller size. Some of these nuclei contained several small crystals. The small crystals occurred at one week following transplantation and were seen even four weeks following transplantation. As time passed, the small crystals appeared to fuse to form larger crystals.

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