Intraoperative fluorescent cholangiography using indocyanine green for laparoscopic fenestration of nonparasitic huge liver cysts

2015 ◽  
Vol 8 (1) ◽  
pp. 71-74 ◽  
Author(s):  
Toshihiro Kitajima ◽  
Yasuhiro Fujimoto ◽  
Etsuro Hatano ◽  
Yusuke Mitsunori ◽  
Koji Tomiyama ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Liver Cysts ◽  
Fluorescent Cholangiography ◽  
Laparoscopic Fenestration

scholarly journals P11: NEAR INFRARED FLUORESCENT CHOLANGIOGRAPHY IN LAPAROSCOPIC CHOLECYSTECTOMY: A SINGLE CENTRE FEASIBILITY STUDY. THE OPTIMUM DOSING REGIME, LIMITATIONS AND WHERE NEXT?

2021 ◽  
Vol 108 (Supplement_1) ◽  
Author(s):  
G Armstrong ◽  
G Toogood ◽  
DG Jayne ◽  
AM Smith
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Bile Duct ◽  
Indocyanine Green ◽  
Feasibility Study ◽  
Near Infrared ◽  
Intravenous Dose ◽  
Structure Identification ◽  
Dosing Regimen ◽  
Single Centre ◽  
Fluorescent Cholangiography

Abstract Introduction This study explored near-infrared fluorescent cholangiography (NIRFC) with Indocyanine Green (ICG) during laparoscopic cholecystectomy (LC) surgery in a tertiary referral hepatobiliary unit. ICG binds to albumin and is excreted in bile. NIRFC utilises the fluorescent and excretory properties of ICG to provide dynamic extrahepatic bile duct mapping during LC. Method Non-randomised single centre feasibility study. Twenty-two participants were sequentially allocated to four dosing subgroups prior to NIRFC assisted LC. Each received a single intravenous dose of ICG prior to LC with the Stryker Novadaq NIR laparoscope. The biliary anatomy was assessed with NIRFC at three time-points, detection was compared to radiological cholangiogram where available and surgeon satisfaction was assessed. Result Eight participants received 2.5mg ICG 20-40min before surgery, four 0.25mg/kg 20-40min, five 90min – 180min and five 12 – 36 hour pre-operatively. Average age 50 years (S.D±15), BMI 27.5m2 (S.D±3.6), 6/22 were acute LC procedures. The prolonged dosing interval produced increased extrahepatic biliary structure identification (p = 0.016), reduced noise to signal ratio and was consistently preferred by the operating surgeon. NIRFC was inferior to radiological cholangiogram (n = 10) (p = 0.014) for bile duct mapping. We observed iatrogenic bile spillage saturating the field and obscuring structure differentiation and peri-hilar inflammation impeding fluorescent detection in acute LC. Conclusion The dosing regimen 0.25mg/kg ICG 12 to 36 hours prior to surgery provides optimum NIRFC structure visualisation. Fluorescent tissue penetrance is limited in acute peri-hilar inflammation. More research in to the efficiency of NIRFC in emergency LC is required. Take-home message An intravenous dose of 0.25mg/kg of Indocyanine Green 12 to 36 hours before surgery is the optimum dosing regimen for increased extra-hepatic bile duct structures with near infrared fluorescent cholangiography. The role of NIRFC in acute laparoscopic cholecystectomy surgery remains ill-defined.

Long-term Patient-reported Outcomes After Laparoscopic Fenestration of Symptomatic Liver Cysts

2017 ◽  
Vol 27 (4) ◽  
pp. e80-e82 ◽  
Author(s):  
Aaron Kisiel ◽  
David G. Vass ◽  
Alex Navarro ◽  
Annie K. John ◽  
Johh Isaac ◽  
...  
Keyword(s):  
Patient Reported Outcomes ◽  
Liver Cysts ◽  
Patient Reported ◽  
Laparoscopic Fenestration

Determination in the optimal time of administering intravenous indocyanine green in fluorescent cholangiography

2015 ◽  
Vol 221 (4) ◽  
pp. e94 ◽  
Author(s):  
Raul J. Rosenthal ◽  
Fernando Dip ◽  
David Nguyen ◽  
Mayank Roy ◽  
Emanuele Lo Menzo ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Optimal Time ◽  
Fluorescent Cholangiography

scholarly journals A Study of Laparoscopic Fenestration of Liver Cysts in Our Department

2020 ◽  
Vol 53 (10) ◽  
pp. 826-834
Author(s):  
Yukino Yoshimura ◽  
Nobumi Tagaya ◽  
Junpei Suzuki ◽  
Yuhei Nakano ◽  
Yako Hasegawa ◽  
...  
Keyword(s):  
Liver Cysts ◽  
Laparoscopic Fenestration

Analysis of unique liver volume restoration after laparoscopic fenestration of liver cysts

2014 ◽  
Vol 7 (2) ◽  
pp. 124-132 ◽  
Author(s):  
Yuji Iimuro ◽  
Toshihiro Okada ◽  
Yuichi Kondo ◽  
Kazuhiro Suzumura ◽  
Naoki Uyama ◽  
...  
Keyword(s):  
Liver Volume ◽  
Liver Cysts ◽  
Laparoscopic Fenestration
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