Profiles of serum soluble programmed death-1 and programmed death-ligand 1 levels in chronic hepatitis B virus-infected patients with different disease phases and after anti-viral treatment

2020 ◽  
Vol 51 (11) ◽  
pp. 1180-1187 ◽  
Author(s):  
Juan Xia ◽  
Rui Huang ◽  
Yuxin Chen ◽  
Yong Liu ◽  
Jian Wang ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Programmed Death Ligand 1 ◽  
Programmed Death ◽  
Chronic Hepatitis B Virus ◽  
B Virus ◽  
Programmed Death 1

scholarly journals Immunomodulatory effects of Tim-3 and PD-1 on chronic hepatitis B virus infection

2018 ◽  
Vol 7 (1) ◽  
pp. 6-11 ◽  
Author(s):  
Yuan Liu
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Immune Cells ◽  
Death Receptor ◽  
Programmed Death ◽  
Chronic Hepatitis B Virus ◽  
B Virus ◽  
Cluster Of Differentiation

Abstract In patients with chronic hepatitis B virus (HBV) infection, the immune cells are dysfunctional, and the immune function cannot work normally. T-cell immunoglobulin mucin-3 (Tim-3) and programmed death receptor-1 (PD-1) are overexpressed on the surface of immune cells, such as cluster of differentiation (CD)4+, CD8+ T-lymphocytes, and natural killer (NK) cells. Many studies indicate that this phenomenon is closely related to the persistence, occurrence, development, and prognosis of HBV. Tim-3 and PD-1 may be used as new immune targets for the treatment of chronic hepatitis B.

Genotype B hepatitis B virus is associated with severe icteric flare-up of chronic hepatitis B virus infection in Hong Kong

2002 ◽  
Vol 97 (10) ◽  
pp. 2629-2633 ◽  
Author(s):  
Henry Lik-Yuen Chan ◽  
Steven Woon-Choi Tsang ◽  
May-Ling Wong ◽  
Chi-Hang Tse ◽  
Nancy Wai-Yee Leung ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hong Kong ◽  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Hepatitis B Virus Infection ◽  
Chronic Hepatitis B Virus ◽  
B Virus
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