scholarly journals Letter: phenotype and natural history of elderly onset inflammatory bowel disease

2018 ◽  
Vol 47 (10) ◽  
pp. 1420-1421 ◽  
Author(s):  
Å. H. Everhov ◽  
J. F. Ludvigsson ◽  
O. Olén
Keyword(s):  
Inflammatory Bowel Disease ◽  
Natural History ◽  
Bowel Disease ◽  
History Of ◽  
Elderly Onset ◽  
Inflammatory Bowel

Mo1314 Natural History of Elderly Onset Inflammatory Bowel Disease - Sydney IBD Cohort (1942-2012)

2013 ◽  
Vol 144 (5) ◽  
pp. S-634-S-635 ◽  
Author(s):  
Viraj C. Kariyawasam ◽  
Tony D. Huang ◽  
Paul C. Lunney ◽  
Kate Middleton ◽  
Rosy R. Wang ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Natural History ◽  
Bowel Disease ◽  
History Of ◽  
Elderly Onset ◽  
Inflammatory Bowel

scholarly journals P631 Natural history of elderly onset inflammatory bowel disease – Sydney IBD Cohort (1942–2012)

2013 ◽  
Vol 7 ◽  
pp. S264
Author(s):  
V. Kariyawasam ◽  
P. Lunney ◽  
T. Huang ◽  
K. Middleton ◽  
R. Wang ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Natural History ◽  
Bowel Disease ◽  
History Of ◽  
Elderly Onset ◽  
Inflammatory Bowel

Phenotype and natural history of elderly onset inflammatory bowel disease: a multicentre, case-control study

2018 ◽  
Vol 47 (5) ◽  
pp. 605-614 ◽  
Author(s):  
M. Mañosa ◽  
M. Calafat ◽  
R. de Francisco ◽  
C. García ◽  
M. J. Casanova ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Natural History ◽  
Bowel Disease ◽  
Case Control Study ◽  
Case Control ◽  
History Of ◽  
Elderly Onset ◽  
Inflammatory Bowel ◽  
Control Study

Epidemiology and Natural History of Elderly-onset Inflammatory Bowel Disease: Results From a Territory-wide Hong Kong IBD Registry

2020 ◽  
Author(s):  
Joyce Wing Yan Mak ◽  
Carmen Lok Tung Ho ◽  
Kylie Wong ◽  
Tsz Yan Cheng ◽  
Terry Cheuk Fung Yip ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Hong Kong ◽  
Natural History ◽  
Bowel Disease ◽  
Cancer Development ◽  
Adult Onset ◽  
Related Hospitalisation ◽  
History Of ◽  
Elderly Onset ◽  
Inflammatory Bowel

Abstract Background Elderly-onset inflammatory bowel disease [IBD], defined as age ≥60 at diagnosis, is increasing worldwide. We aimed to compare clinical characteristics and natural history of elderly-onset IBD patients with those of adult-onset IBD patients. Methods Patients with a confirmed diagnosis of IBD from 1981 to 2016 were identified from a territory-wide Hong Kong IBD registry involving 13 hospitals. Demographics, comorbidities, clinical features, and outcomes of elderly-onset IBD patients were compared with those of adult-onset IBD patients. Results A total of 2413 patients were identified, of whom 270 [11.2%] had elderly-onset IBD. Median follow-up duration was 111 months (interquartile range [IQR]: 68–165 months). Ratio of ulcerative colitis [UC]: Crohn’s disease [CD] was higher in elderly-onset IBD than in adult-onset IBD patients [3.82:1 vs 1.39:1; p <0.001]. Elderly-onset CD had less perianal involvement [5.4% vs 25.4%; p <0.001] than adult-onset CD. Elderly-onset IBD patients had significantly lower cumulative use of immunomodulators [p = 0.001] and biologics [p = 0.04]. Elderly-onset IBD was associated with higher risks of: cytomegalovirus colitis (odds ratio [OR]: 3.07; 95% confidence interval [CI] 1.92–4.89; p <0.001); herpes zoster [OR: 2.42; 95% CI 1.22–4.80; p = 0.12]; and all cancer development [hazard ratio: 2.97; 95% CI 1.84–4.79; p <0.001]. They also had increased number of overall hospitalisations [OR: 1.14; 95% CI 1.09–1.20; p <0.001], infections-related hospitalisation [OR: 1.87; 95% CI 1.47–2.38; p <0.001], and IBD-related hospitalisation [OR: 1.09; 95% CI 1.04- 1.15; p = 0.001] compared with adult-onset IBD patients. Conclusions Elderly-onset IBD was associated with increased risk of infections and cancer development, and increased infection- and IBD-related hospitalisations. Specific therapeutic strategies to target this special population are needed.

scholarly journals Natural History of Elderly-onset Ulcerative Colitis: Results from a Territory-wide Inflammatory Bowel Disease Registry

2015 ◽  
Vol 10 (2) ◽  
pp. 176-185 ◽  
Author(s):  
Hai Yun Shi ◽  
Francis K. L. Chan ◽  
Wai Keung Leung ◽  
Michael K. K. Li ◽  
Chi Man Leung ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Natural History ◽  
Bowel Disease ◽  
Disease Registry ◽  
History Of ◽  
Elderly Onset ◽  
Inflammatory Bowel

Natural history of elderly-onset inflammatory bowel disease: a population-based cohort study

Gut ◽  
2013 ◽  
Vol 63 (3) ◽  
pp. 423-432 ◽  
Author(s):  
Cloé Charpentier ◽  
Julia Salleron ◽  
Guillaume Savoye ◽  
Mathurin Fumery ◽  
Véronique Merle ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Cohort Study ◽  
Natural History ◽  
Bowel Disease ◽  
Population Based ◽  
History Of ◽  
Elderly Onset ◽  
Inflammatory Bowel

scholarly journals P806 Natural history of Paediatric Black British inflammatory bowel disease

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S520-S520
Author(s):  
A -M Grima ◽  
C Ilesley ◽  
G Dawson ◽  
A Driscoll ◽  
B Hope ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Natural History ◽  
Bowel Disease ◽  
Black British ◽  
History Of ◽  
Inflammatory Bowel
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