scholarly journals Treatment of refractory ascites with an automated low-flow ascites pump in patients with cirrhosis

2017 ◽  
Vol 46 (10) ◽  
pp. 981-991 ◽  
Author(s):  
G. Stirnimann ◽  
T. Berg ◽  
L. Spahr ◽  
S. Zeuzem ◽  
S. McPherson ◽  
...  
Keyword(s):  
Low Flow ◽  
Refractory Ascites ◽  
Automated Low Flow

scholarly journals Automated low-flow ascites pump for the treatment of cirrhotic patients with refractory ascites

2017 ◽  
Vol 10 (2) ◽  
pp. 283-292 ◽  
Author(s):  
Guido Stirnimann ◽  
Vanessa Banz ◽  
Federico Storni ◽  
Andrea De Gottardi
Keyword(s):  
Low Flow ◽  
Refractory Ascites ◽  
Organ Shortage ◽  
Efficacy And Safety ◽  
Novel Treatments ◽  
Intrahepatic Portosystemic Shunt ◽  
Cirrhotic Patients ◽  
Large Volume Paracentesis ◽  
Volume Controlled ◽  
Automated Low Flow

Cirrhotic patients with refractory ascites (RA) can be treated with repeated large volume paracentesis (LVP), with the insertion of a transjugular intrahepatic portosystemic shunt (TIPS) or with liver transplantation. However, side effects and complications of these therapeutic options, as well as organ shortage, warrant the development of novel treatments. The automated low-flow ascites pump (alfapump®) is a subcutaneously-implanted novel battery-driven device that pumps ascitic fluid from the peritoneal cavity into the urinary bladder. Ascites can therefore be aspirated in a time- and volume-controlled mode and evacuated by urination. Here we review the currently available data about patient selection, efficacy and safety of the alfapump and provide recommendations for the management of patients treated with this new method.

Systematic review with meta-analysis: automated low-flow ascites pump therapy for refractory ascites

2019 ◽  
Vol 50 (9) ◽  
pp. 978-987 ◽  
Author(s):  
Antonia Lepida ◽  
Astrid Marot ◽  
Eric Trépo ◽  
Delphine Degré ◽  
Christophe Moreno ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Low Flow ◽  
Refractory Ascites ◽  
Pump Therapy ◽  
Automated Low Flow

scholarly journals Radiological insertion of automated low flow ascitic pump (alfapump®) system for management of medically refractory ascites

2017 ◽  
Vol 3 (4) ◽  
pp. 20170025 ◽  
Author(s):  
Salil Karkhanis ◽  
Robert Jones ◽  
Andrew Willis ◽  
Eoghan Mccarthy ◽  
Zergham Zia ◽  
...  
Keyword(s):  
Low Flow ◽  
Refractory Ascites ◽  
Automated Low Flow

P523 SAFETY AND EFFICACY OF AN AUTOMATED LOW FLOW ASCITES (ALFA) PUMP IN CIRRHOTIC PATIENTS WITH REFRACTORY ASCITES

2014 ◽  
Vol 60 (1) ◽  
pp. S244 ◽  
Author(s):  
A. De Gottardi ◽  
V. Banz ◽  
F. Storni ◽  
G. Stirnimann ◽  
N. Semmo ◽  
...  
Keyword(s):  
Low Flow ◽  
Refractory Ascites ◽  
Safety And Efficacy ◽  
Cirrhotic Patients ◽  
Automated Low Flow

Automated low flow pump system for the treatment of refractory ascites: A multi-center safety and efficacy study

2013 ◽  
Vol 58 (5) ◽  
pp. 922-927 ◽  
Author(s):  
Pablo Bellot ◽  
Martin-Walter Welker ◽  
German Soriano ◽  
Markus von Schaewen ◽  
Beate Appenrodt ◽  
...  
Keyword(s):  
Low Flow ◽  
Refractory Ascites ◽  
Efficacy Study ◽  
Pump System ◽  
Safety And Efficacy ◽  
Automated Low Flow ◽  
Flow Pump

scholarly journals Treatment of refractory ascites with an automated low flow ascites pump in patients awaiting liver transplantation

2021 ◽  
Vol 4 ◽  
pp. 100037
Author(s):  
Federico Storni ◽  
Jessica Stirnimann ◽  
Vanessa Banz ◽  
Andrea De Gottardi ◽  
Guido Stirnimann
Keyword(s):  
Liver Transplantation ◽  
Low Flow ◽  
Refractory Ascites ◽  
Automated Low Flow

Automated low flow pump system for the treatment of refractory ascites: a single-center experience

2015 ◽  
Vol 400 (8) ◽  
pp. 979-983 ◽  
Author(s):  
M. N. Thomas ◽  
G. H. Sauter ◽  
A. L. Gerbes ◽  
M. Stangl ◽  
T. S. Schiergens ◽  
...  
Keyword(s):  
Low Flow ◽  
Refractory Ascites ◽  
Single Center ◽  
Pump System ◽  
Single Center Experience ◽  
Automated Low Flow ◽  
Flow Pump

scholarly journals Current management of refractory ascites in patients with cirrhosis

2017 ◽  
Vol 46 (3) ◽  
pp. 1138-1145 ◽  
Author(s):  
Ruihong Zhao ◽  
Juan Lu ◽  
Yu Shi ◽  
Hong Zhao ◽  
Kaijin Xu ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Poor Quality ◽  
Low Flow ◽  
Refractory Ascites ◽  
Pump System ◽  
Choice Of Treatment ◽  
Intrahepatic Portosystemic Shunt ◽  
Therapeutic Measures ◽  
Large Volume Paracentesis ◽  
Traditional Approaches

Liver cirrhosis is a health problem worldwide, and ascites is its principal symptom. Refractory ascites is intractable and occurs in 5%–10% of all patients with ascites due to cirrhosis. Refractory ascites leads to a poor quality of life and high mortality rate. Ascites develops as a result of portal hypertension, which leads to water–sodium retention and renal failure. Various therapeutic measures can be used for refractory ascites, including large-volume paracentesis, transjugular intrahepatic portosystemic shunt, vasoconstrictive drugs, and an automated low-flow ascites pump system. However, ascites generally can be resolved only by liver transplantation. Because not all patients can undergo liver transplantation, traditional approaches are still used to treat refractory ascites. The choice of treatment modality for refractory ascites depends, among other factors, on the condition of the patient.

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