scholarly journals Editorial: risk factors for persistent villus atrophy in coeliac disease - is it time to reconsider definitions for refractory coeliac disease? Authors' reply

2017 ◽  
Vol 45 (11) ◽  
pp. 1478-1479
Author(s):  
S. Mahadev ◽  
J. A. Murray ◽  
P. H. R. Green ◽  
D. A. Adelman ◽  
B. Lebwohl
Keyword(s):  
Risk Factors ◽  
Coeliac Disease ◽  
Villus Atrophy ◽  
Refractory Coeliac Disease

Refractory coeliac disease type I and II; Pilot-treatment with azathioprine and predinison

2001 ◽  
Vol 120 (5) ◽  
pp. A131-A131 ◽  
Author(s):  
C MULDER ◽  
P WAHAB ◽  
A TAN ◽  
J MEIJER
Keyword(s):  
Coeliac Disease ◽  
Disease Type ◽  
Type I ◽  
Refractory Coeliac Disease

scholarly journals Faecal Scent as a Novel Non-Invasive Biomarker to Discriminate between Coeliac Disease and Refractory Coeliac Disease: A Proof of Principle Study

Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 69 ◽  
Author(s):  
Maxine D. Rouvroye ◽  
Alfian Wicaksono ◽  
Sofie Bosch ◽  
Edo Savelkoul ◽  
James A. Covington ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Ion Mobility ◽  
Clinical Symptoms ◽  
Area Under The Curve ◽  
Gluten Free ◽  
Future Studies ◽  
Non Invasive ◽  
Significant Difference ◽  
Volatile Organic ◽  
Refractory Coeliac Disease

Currently, the gold standard for diagnosis of coeliac disease (CD) is based on serology and gastroduodenoscopy with histology of duodenal mucosal biopsies. The aim of this study was to evaluate the potential of faecal volatile organic compounds (VOCs) analysis as a novel, non-invasive tool to discriminate between CD in remission in patients on a gluten-free diet (GFD), refractory coeliac disease (RCD) and controls without CD. Patients with an established diagnosis of CD on a GFD, RCD and healthy controls (HC) were instructed to collect a faecal sample. All subjects completed questionnaires on clinical symptoms, lifestyle and dietary information. Faecal VOCs were measured using gas chromatography-ion mobility spectrometry. A total of 13 CD, 7 RCD and 10 HC were included. A significant difference in VOC profiles between CD and RCD patients (area under the curve (AUC) ± 95% CI: 0.91 (0.79–1) p = 0.000) and between CD and HC (AUC ± 95% CI: 0.71 (0.51–0.91) p = 0.0254) was observed. We found no significant differences between faecal VOC patterns of HC and RCD. Based on faecal VOCs, CD could be discriminated from RCD and HC. This implies that faecal VOC analysis may hold potential as a novel non-invasive biomarker for RCD. Future studies should encompass a larger cohort to further investigate and validate this prior to application in clinical practice.

scholarly journals Refractory Coeliac Disease, Small-Bowel Lymphoma and Chorea

2002 ◽  
Vol 95 (3) ◽  
pp. 133-134 ◽  
Author(s):  
T Kitiyakara ◽  
M Jackson ◽  
D A Gorard
Keyword(s):  
Small Bowel ◽  
Coeliac Disease ◽  
Refractory Coeliac Disease

scholarly journals Myoclonus ataxia and refractory coeliac disease

2014 ◽  
Vol 1 (1) ◽  
Author(s):  
Ptolemaios G Sarrigiannis ◽  
Nigel Hoggard ◽  
Daniel Aeschlimann ◽  
David S Sanders ◽  
Richard A Grünewald ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Refractory Coeliac Disease

Refractory coeliac disease

2020 ◽  
Vol 36 (3) ◽  
pp. 215-222
Author(s):  
Stefania Chetcuti Zammit ◽  
David S. Sanders ◽  
Reena Sidhu
Keyword(s):  
Coeliac Disease ◽  
Refractory Coeliac Disease

Refractory coeliac disease a reality: views from Pakistan

2016 ◽  
Vol 47 (1) ◽  
pp. 51-53
Author(s):  
Rajesh M Mandhwani ◽  
Rajesh K Wadhwa ◽  
Syed Mudassir Laeeq ◽  
Nasir Hasan Luck ◽  
Mohammad Mubarak ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Villous Atrophy ◽  
Immunosuppressive Agents ◽  
Signs And Symptoms ◽  
Intraepithelial Lymphocytes ◽  
Response To Treatment ◽  
Gluten Free ◽  
Refractory Celiac Disease ◽  
Small Intestinal ◽  
Refractory Coeliac Disease

Refractory coeliac disease (RCD) is described as persistence or recurrence of signs and symptoms of malabsorption with small-intestinal villous atrophy despite being on a strict gluten-free diet (GFD) for more than 12 months. RCD is a diagnosis of exclusion. There are two types of RCD, based upon the immunohistochemical features (presence of intraepithelial lymphocytes), response to treatment and prognosis. The treatment of RCD includes GFD and immunosuppressive agents. We hereby present a case of refractory celiac disease type II in a young man who later went on to develop Addisonian crisis and did not survive.

scholarly journals PTH-115 Prevalence Rates And Risk Factors For Osteoporosis In Patients With Coeliac Disease

Gut ◽  
2014 ◽  
Vol 63 (Suppl 1) ◽  
pp. A261.3-A262
Author(s):  
J Schembri ◽  
P Torpiano ◽  
N Azzopardi ◽  
M Vassallo ◽  
P Ellul
Keyword(s):  
Risk Factors ◽  
Coeliac Disease ◽  
Prevalence Rates

scholarly journals T-cell repertoires in refractory coeliac disease

Gut ◽  
2017 ◽  
pp. gutjnl-2016-311816 ◽  
Author(s):  
Julia Ritter ◽  
Karin Zimmermann ◽  
Korinna Jöhrens ◽  
Stefanie Mende ◽  
Anke Seegebarth ◽  
...  
Keyword(s):  
T Cell ◽  
Coeliac Disease ◽  
Refractory Coeliac Disease
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