scholarly journals Review article: the potential mechanisms of action of rifaximin in the management of inflammatory bowel diseases

2015 ◽  
Vol 43 ◽  
pp. 27-36 ◽  
Author(s):  
R. B. Sartor
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Mechanisms Of Action ◽  
Review Article ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Review article: fungal alterations in inflammatory bowel diseases

2019 ◽  
Vol 50 (11-12) ◽  
pp. 1159-1171 ◽  
Author(s):  
Siu Lam ◽  
Tao Zuo ◽  
Martin Ho ◽  
Francis K. L. Chan ◽  
Paul K. S. Chan ◽  
...  
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Review Article ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Review article: mesenchymal stromal cell therapy for inflammatory bowel diseases

2016 ◽  
Vol 45 (2) ◽  
pp. 205-221 ◽  
Author(s):  
C. Grégoire ◽  
C. Lechanteur ◽  
A. Briquet ◽  
É. Baudoux ◽  
F. Baron ◽  
...  
Keyword(s):  
Cell Therapy ◽  
Inflammatory Bowel Diseases ◽  
Mesenchymal Stromal Cell ◽  
Stromal Cell ◽  
Review Article ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Microbiota-independent immunological effects of non-digestible oligosaccharides in the context of inflammatory bowel diseases

2020 ◽  
Vol 79 (4) ◽  
pp. 468-478 ◽  
Author(s):  
Stefania Del Fabbro ◽  
Philip C. Calder ◽  
Caroline E. Childs
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Immune Cell ◽  
Intestinal Inflammation ◽  
Mechanisms Of Action ◽  
Mucosal Inflammation ◽  
Disease States ◽  
Inflammatory Conditions ◽  
Bowel Diseases ◽  
Inflammatory Bowel

The aim of the present paper is to review the effects of non-digestible oligosaccharides (NDO) on immunity, focusing on their microbiota-independent mechanisms of action, as well as to explore their potential beneficial role in inflammatory bowel diseases (IBD). IBD are chronic, inflammatory conditions of the gastrointestinal tract. Individuals with IBD have an aberrant immune response to commensal microbiota, resulting in extensive mucosal inflammation and increased intestinal permeability. NDO are prebiotic fibres well known for their role in supporting intestinal health through modulation of the gut microbiota. NDO reach the colon intact and are fermented by commensal bacteria, resulting in the production of SCFA with immunomodulatory properties. In disease states characterised by increased gut permeability, prebiotics may also bypass the gut barrier and directly interact with intestinal and systemic immune cells, as demonstrated in patients with IBD and in infants with an immature gut. In vitro models show that fructooligosaccharides, inulin and galactooligosaccharides exert microbiota-independent effects on immunity by binding to toll-like receptors on monocytes, macrophages and intestinal epithelial cells and by modulating cytokine production and immune cell maturation. Moreover, animal models and human supplementation studies demonstrate that some prebiotics, including inulin and lactulose, might reduce intestinal inflammation and IBD symptoms. Although there are convincing preliminary data to support NDO as immunomodulators in the management of IBD, their mechanisms of action are still unclear and larger standardised studies need to be performed using a wider range of prebiotics.

Review article: bugs, inflammation and mood-a microbiota-based approach to psychiatric symptoms in inflammatory bowel diseases

2020 ◽  
Vol 52 (2) ◽  
pp. 247-266 ◽  
Author(s):  
Anne K. Thomann ◽  
Joyce W. Y. Mak ◽  
Jing Wan Zhang ◽  
Torsten Wuestenberg ◽  
Matthias P. Ebert ◽  
...  
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Psychiatric Symptoms ◽  
Review Article ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Review article: breath analysis in inflammatory bowel diseases

2014 ◽  
Vol 41 (4) ◽  
pp. 329-341 ◽  
Author(s):  
S. Kurada ◽  
N. Alkhouri ◽  
C. Fiocchi ◽  
R. Dweik ◽  
F. Rieder
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Breath Analysis ◽  
Review Article ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Review article: pharmacological aspects of anti-TNF biosimilars in inflammatory bowel diseases

2015 ◽  
Vol 42 (10) ◽  
pp. 1158-1169 ◽  
Author(s):  
K. Papamichael ◽  
T. Van Stappen ◽  
V. Jairath ◽  
K. Gecse ◽  
R. Khanna ◽  
...  
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Review Article ◽  
Bowel Diseases ◽  
Inflammatory Bowel
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