scholarly journals Letter: sleep and psychological disorders in patients with inflammatory bowel diseases; another potential role of vitamin D deficiency

2014 ◽  
Vol 39 (5) ◽  
pp. 548-548
Author(s):  
A. Gholamrezaei ◽  
M. H. Emami
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Inflammatory Bowel Diseases ◽  
Potential Role ◽  
Psychological Disorders ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Role of vitamin D derivatives in intestinal tissue of patients with inflammatory bowel diseases

2014 ◽  
Vol 8 (9) ◽  
pp. 1062-1071 ◽  
Author(s):  
Maria Martinesi ◽  
Stefano Ambrosini ◽  
Cristina Treves ◽  
Ulrich Zuegel ◽  
Andreas Steinmeyer ◽  
...  
Keyword(s):  
Vitamin D ◽  
Inflammatory Bowel Diseases ◽  
Intestinal Tissue ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Evidence for a Potential Role of Metallothioneins in Inflammatory Bowel Diseases

2009 ◽  
Vol 2009 ◽  
pp. 1-9 ◽  
Author(s):  
Anouk Waeytens ◽  
Martine De Vos ◽  
Debby Laukens
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Potential Role ◽  
Current Knowledge ◽  
Zinc Homeostasis ◽  
Central Position ◽  
Small Proteins ◽  
Immune Mediated ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Inflammatory bowel diseases (IBDs) are a group of chronic, relapsing, immune-mediated disorders of the intestine, including Crohn's disease and ulcerative colitis. Recent studies underscore the importance of the damaged epithelial barrier and the dysregulated innate immune system in their pathogenesis. Metallothioneins (MTs) are a family of small proteins with a high and conserved cysteine content that are rapidly upregulated in response to an inflammatory stimulus. Herein, we review the current knowledge regarding the expression and potential role of MTs in IBD. MTs exert a central position in zinc homeostasis, modulate the activation of the transcription factor nuclear factor (NF)-B, and serve as antioxidants. In addition, MTs could be involved in IBD through their antiapoptotic effects or through specific immunomodulating extracellular effects. Reports on MT expression in IBD are contradictory but clearly demonstrate a deviant MT expression supporting the idea that these aberrations in IBD require further clarification.

Factors affecting vitamin D deficiency in active inflammatory bowel diseases

2019 ◽  
Vol 51 (5) ◽  
pp. 657-662 ◽  
Author(s):  
Giorgia Burrelli Scotti ◽  
Maria Teresa Afferri ◽  
Aurora De Carolis ◽  
Valentina Vaiarello ◽  
Valeria Fassino ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Inflammatory Bowel Diseases ◽  
Factors Affecting ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Vitamin D level in Hungarian patients with inflammatory bowel diseases

2013 ◽  
Vol 154 (46) ◽  
pp. 1821-1828 ◽  
Author(s):  
Katalin Lőrinczy ◽  
Péter László Lakatos ◽  
Miklós Tóth ◽  
Ágnes Salamon ◽  
Adrienn Nemes ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Inflammatory Bowel Diseases ◽  
Bowel Disease ◽  
Activity Index ◽  
Disease Activity Index ◽  
Clinical Activity ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Introduction: Vitamin D has an important role in the immune regulation. Vitamin D is essential for innate and adaptive immune systems and it plays a significant role in the formation of immune tolerance, as well. Aim: Vitamin D deficiency has been observed in patients with inflammatory bowel diseases in Western Europe, but there is no data available from Eastern Europe. Method: The study included 169 patients with inflammatory bowel disease. Results: The median vitamin D level was 22.7±10.6 ng/ml. Only 20% of the patients had adequate vitamin D level (>30 ng/ml), 52% had vitamin D insufficiency (15–30 ng/ml), and 28% of them had severe vitamin D deficiency (<15 ng/ml). Vitamin D concentration failed to correlate with clinical activity indexes (partial Mayo score: r = –0.143; Crohn’s disease activity index: r = –0.253) and with inflammatory parameters (C-reactive protein: r = 0.008; erythrocyte sedimentation rate: r = 0.012). Conclusions: Since vitamin D deficiency can be frequently observed in Hungarian patients with inflammatory bowel disease, its level should be tested in these patients. Orv. Hetil., 154(46), 1821–1828.

Vitamin D Deficiency Associated with Disease Activity in Patients with Inflammatory Bowel Diseases

2015 ◽  
Vol 60 (10) ◽  
pp. 3085-3091 ◽  
Author(s):  
Mehdi Torki ◽  
Ali Gholamrezaei ◽  
Leila Mirbagher ◽  
Manijeh Danesh ◽  
Sara Kheiri ◽  
...  
Keyword(s):  
Vitamin D ◽  
Disease Activity ◽  
Vitamin D Deficiency ◽  
Inflammatory Bowel Diseases ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Do Only Calcium and Vitamin D Matter? Micronutrients in the Diet of Inflammatory Bowel Diseases Patients and the Risk of Osteoporosis

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 525
Author(s):  
Alicja Ewa Ratajczak ◽  
Anna Maria Rychter ◽  
Agnieszka Zawada ◽  
Agnieszka Dobrowolska ◽  
Iwona Krela-Kaźmierczak
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Inflammatory Bowel Diseases ◽  
Bone Mineralization ◽  
Mineral Density ◽  
Bowel Diseases ◽  
Prevention Of Osteoporosis ◽  
Inflammatory Bowel ◽  
Extraintestinal Complications

Osteoporosis is one of the most common extraintestinal complications among patients suffering from inflammatory bowel diseases. The role of vitamin D and calcium in the prevention of a decreased bone mineral density is well known, although other nutrients, including micronutrients, are also of extreme importance. Despite the fact that zinc, copper, selenium, iron, cadmium, silicon and fluorine have not been frequently discussed with regard to the prevention of osteoporosis, it is possible that a deficiency or excess of the abovementioned elements may affect bone mineralization. Additionally, the risk of malnutrition, which is common in patients with ulcerative colitis or Crohn’s disease, as well as the composition of gut microbiota, may be associated with micronutrients status.

Vitamin D deficiency in patients with either rheumatic diseases or inflammatory bowel diseases on biologic therapy

2016 ◽  
Vol 11 (6) ◽  
pp. 803-807 ◽  
Author(s):  
Vincenzo Bruzzese ◽  
Angelo Zullo ◽  
Andrea Piacchianti Diamanti ◽  
Lorenzo Ridola ◽  
Roberto Lorenzetti ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Rheumatic Diseases ◽  
Inflammatory Bowel Diseases ◽  
Biologic Therapy ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Erratum to: Vitamin D deficiency in patients with either rheumatic diseases or inflammatory bowel diseases on biologic therapy

2016 ◽  
Vol 12 (1) ◽  
pp. 141-141
Author(s):  
Vincenzo Bruzzese ◽  
Angelo Zullo ◽  
Andrea Picchianti Diamanti ◽  
Lorenzo Ridola ◽  
Roberto Lorenzetti ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Rheumatic Diseases ◽  
Inflammatory Bowel Diseases ◽  
Biologic Therapy ◽  
Bowel Diseases ◽  
Inflammatory Bowel
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