scholarly journals Linking intermittent hypoxia, sympathetic response and metabolic disturbances

2013 ◽  
Vol 209 (1) ◽  
pp. 7-8
Author(s):  
A. Nadal
Keyword(s):  
Intermittent Hypoxia ◽  
Metabolic Disturbances ◽  
Sympathetic Response

Sympathetic response to chemostimulation in conscious rats exposed to chronic intermittent hypoxia

2009 ◽  
Vol 166 (2) ◽  
pp. 102-106 ◽  
Author(s):  
Jianhua Huang ◽  
Sara Lusina ◽  
Tian Xie ◽  
Ensheng Ji ◽  
Shuanglin Xiang ◽  
...  
Keyword(s):  
Intermittent Hypoxia ◽  
Chronic Intermittent Hypoxia ◽  
Sympathetic Response ◽  
Conscious Rats

scholarly journals PACAP-PAC1 Receptor Activation Is Necessary for the Sympathetic Response to Acute Intermittent Hypoxia

2019 ◽  
Vol 13 ◽  
Author(s):  
Melissa M. J. Farnham ◽  
Vikram J. Tallapragada ◽  
Edward T. O’Connor ◽  
Polina E. Nedoboy ◽  
Bowen Dempsey ◽  
...  
Keyword(s):  
Intermittent Hypoxia ◽  
Receptor Activation ◽  
Pac1 Receptor ◽  
Sympathetic Response

scholarly journals Cyclic intermittent hypoxia enhances renal sympathetic response to ICV ET-1 in conscious rats

2010 ◽  
Vol 171 (2) ◽  
pp. 83-89 ◽  
Author(s):  
Jianhua Huang ◽  
Tian Xie ◽  
Yuming Wu ◽  
Xianghong Li ◽  
Sara Lusina ◽  
...  
Keyword(s):  
Intermittent Hypoxia ◽  
Sympathetic Response ◽  
Conscious Rats ◽  
Renal Sympathetic

Pathology of Bone Cells in Pigs with Experimental Turbinate Osteoporosis (Atrophic Rhinitis)

1971 ◽  
Vol 29 ◽  
pp. 304-305
Author(s):  
A. W. Fetter ◽  
C. C. Capen
Keyword(s):  
Mucous Membrane ◽  
Bone Cells ◽  
Atrophic Rhinitis ◽  
Infectious Agents ◽  
Metabolic Disturbances ◽  
Progressive Reduction ◽  
Naturally Occurring ◽  
Fundamental Cause ◽  
Osteocytic Osteolysis ◽  
Uncertain Etiology

Atrophic rhinitis in swine is a disease of uncertain etiology in which infectious agents, hereditary predisposition, and metabolic disturbances have been reported to be of primary etiologic importance. It shares many similarities, both clinically and pathologically, with ozena in man. The disease is characterized by deformity and reduction in volume of the nasal turbinates. The fundamental cause for the localized lesion of bone in the nasal turbinates has not been established. Reduced osteogenesis, increased resorption related to inflammation of the nasal mucous membrane, and excessive resorption due to osteocytic osteolysis stimulated by hyperparathyroidism have been suggested as possible pathogenetic mechanisms.The objectives of this investigation were to evaluate ultrastructurally bone cells in the nasal turbinates of pigs with experimentally induced atrophic rhinitis, and to compare these findings to those in control pigs of the same age and pigs with the naturally occurring disease, in order to define the fundamental lesion responsible for the progressive reduction in volume of the osseous core.

The role of vitamin D in metabolic and reproductive disturbances of polycystic ovary syndrome: A narrative mini-review

2020 ◽  
pp. 1-8
Author(s):  
Daniela Menichini ◽  
Gianpiero Forte ◽  
Beatrice Orrù ◽  
Giuseppe Gullo ◽  
Vittorio Unfer ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Embryo Quality ◽  
Polycystic Ovary ◽  
Vitamin D Supplementation ◽  
Endometrial Receptivity ◽  
Metabolic Disturbances ◽  
Ovary Syndrome ◽  
Beneficial Role

Abstract. Vitamin D is a secosteroid hormone that plays a pivotal role in several metabolic and reproductive pathways in humans. Increasing evidence supports the role of vitamin D deficiency in metabolic disturbances and infertility in women with polycystic ovary syndrome (PCOS). Indeed, supplementation with vitamin D seems to have a beneficial role on insulin resistance and endometrial receptivity. On the other hand, exceedingly high levels of vitamin D appear to play a detrimental role on oocytes development and embryo quality. In the current review, we summarize the available evidence about the topic, aiming to suggest the best supplementation strategy in women with PCOS or, more generally, in those with metabolic disturbances and infertility. Based on the retrieved data, vitamin D seems to have a beneficial role on IR, insulin sensitivity and endometrial receptivity, but high levels and incorrect timing of administration seem to have a detrimental role on oocytes development and embryo quality. Therefore, we encourage a low dose supplementation (400–800 IU/day) particularly in vitamin D deficient women that present metabolic disturbances like PCOS. As far as the reproductive health, we advise vitamin D supplementation in selected populations, only during specific moments of the ovarian cycle, to support the luteal phase. However, ambiguities about dosage and timing of the supplementation still emerge from the clinical studies published to date and further studies are required.

Sign in / Sign up

Export Citation Format

Share Document