The Silverman Andersen respiratory severity score in the delivery room predicts subsequent intubation in very preterm neonates

2020 ◽  
Author(s):  
Anna B. Hedstrom ◽  
Anna V. Faino ◽  
Maneesh Batra
Keyword(s):  
Severity Score ◽  
Delivery Room ◽  
Preterm Neonates ◽  
Very Preterm

Immediate Effects of Phototherapy on Sleep of Very Preterm Neonates: An Observational Study

2015 ◽  
Vol 46 (S 01) ◽  
Author(s):  
M. Cremer ◽  
K. Jost ◽  
S. Schulzke ◽  
P. Weber ◽  
A. Datta
Keyword(s):  
Observational Study ◽  
Preterm Neonates ◽  
Very Preterm

Placental Transfusion, Timing of Plastic Wrap or Bag Placement, and Preterm Neonates

2021 ◽  
Author(s):  
William Engle ◽  
Izlin Lien ◽  
Brian Benneyworth ◽  
Jennifer Stanton Tully ◽  
Alana Barbato ◽  
...  
Keyword(s):  
Necrotizing Enterocolitis ◽  
Outcome Data ◽  
Delivery Room ◽  
Respiratory Support ◽  
Preterm Neonates ◽  
Quality Improvement Initiative ◽  
Delayed Cord Clamping ◽  
Cord Clamping ◽  
Simultaneous Group ◽  
Sequential Group

Objective Compare delivery room practices and outcomes of infants born at less than 32 weeks' gestation or less than 1,500 g who have plastic wrap/bag placement simultaneously during placental transfusion to those receiving plastic wrap/bag placement sequentially following placental transfusion. Study Design Retrospective analysis of data from a multisite quality improvement initiative to refine stabilization procedures pertaining to placental transfusion and thermoregulation using a plastic wrap/bag. Delivery room practices and outcome data in 590 total cases receiving placental transfusion were controlled for propensity score matching and hospital of birth. Results The simultaneous and sequential groups were similar in demographic and most outcome metrics. The simultaneous group had longer duration of delayed cord clamping compared with the sequential group (42.3 ± 14.8 vs. 34.1 ± 10.3 seconds, p < 0.001), and fewer number of times cord milking was performed (0.41 ± 1.26 vs. 0.86 ± 1.92 seconds, p < 0.001). The time to initiate respiratory support was also significantly shorter in the simultaneous group (97.2 ± 100.6 vs. 125.2 ± 177.6 seconds, p = 0.02). The combined outcome of death or necrotizing enterocolitis in the simultaneous group was more frequent than in the sequential group (15.3 vs. 9.3%, p = 0.038); all other outcomes measured were similar. Conclusion Timing of plastic wrap/bag placement during placental transfusion did affect duration of delayed cord clamping, number of times cord milking was performed, and time to initiate respiratory support in the delivery room but did not alter birth hospital outcomes or respiratory care practices other than the combined outcome of death or necrotizing enterocolitis. Key Points

scholarly journals Optimized T1- and T2-weighted volumetric brain imaging as a diagnostic tool in very preterm neonates

2010 ◽  
Vol 41 (6) ◽  
pp. 702-710 ◽  
Author(s):  
Revital Nossin-Manor ◽  
Andrew D. Chung ◽  
Drew Morris ◽  
João P. Soares-Fernandes ◽  
Bejoy Thomas ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Diagnostic Tool ◽  
Preterm Neonates ◽  
Very Preterm ◽  
T1 And T2

Long-term effects of pain in infants

2021 ◽  
pp. 38-46
Author(s):  
Ruth E. Grunau ◽  
Jillian Vinall Miller ◽  
Cecil M. Y. Chau
Keyword(s):  
Preterm Infants ◽  
Neonatal Intensive Care ◽  
Pain Treatment ◽  
Inflammatory Responses ◽  
Imaging Techniques ◽  
Preterm Neonates ◽  
Long Term Effects ◽  
Very Preterm Infants ◽  
Very Preterm

The long-term effects of infant pain are complex, and vary depending on how early in life the exposure occurs, due to differences in developmental maturity of specific systems underway. Changes to later pain sensitivity reflect multiple factors such as age at pain stimulation, extent of tissue damage, type of noxious insult, intensity, and duration. In both full-term and preterm infants exposed to hospitalization, sequelae of early pain are confounded by parental separation and quality of pain treatment. Neonates born very preterm are outside the protective uterine environment, with repeated exposure to pain occurring during fetal life. Especially for infants born in the late second trimester, the cascade of autonomic, hormonal, and inflammatory responses to procedures may induce excitotoxicity with widespread effects on the brain. Quantitative advanced imaging techniques have revealed that neonatal pain in very preterm infants is associated with altered brain development during the neonatal period and beyond. Recent studies now provide evidence of pathways reflecting mechanisms that may underlie the emerging association between cumulative procedural pain exposure and neurodevelopment and behavior in children born very preterm. Owing to immaturity of the central nervous system, repetitive pain in very preterm neonates contributes to alterations in multiple aspects of development. Importantly, there is strong evidence that parental caregiving to reduce pain and stress in preterm infants in the Neonatal Intensive Care Unit (NICU) may prevent adverse effects, and sensitive parenting after NICU discharge may help ameliorate potential long-term effects.

scholarly journals Relationship between arginine intake in parenteral nutrition and preterm neonatal population plasma arginine concentrations: a systematic review

2019 ◽  
Vol 77 (12) ◽  
pp. 878-889
Author(s):  
Chandini M Premakumar ◽  
Mark A Turner ◽  
Colin Morgan
Keyword(s):  
Systematic Review ◽  
Parenteral Nutrition ◽  
Study Design ◽  
Data Extraction ◽  
Research Question ◽  
Preterm Neonates ◽  
Very Preterm ◽  
Dose Concentration ◽  
Plasma Arginine ◽  
Relationship Of

AbstractContextVery preterm neonates (VPNs) are unable to digest breast milk and therefore rely on parenteral nutrition (PN) formulations. This systematic review was prepared following PRISMA-P 2015 guidelines. For the purpose of this review, desirable mean plasma arginine concentration is defined as ≥80 micromoles/L.ObjectiveThe review was performed to answer the following research question: “In VPNs, are high amounts of arginine in PN, compared with low amounts of arginine, associated with appropriate circulating concentrations of arginine?” Therefore, the aims were to 1) quantify the relationship between parenteral arginine intakes and plasma arginine concentrations in PN-dependent VPNs; 2) identify any features of study design that affect this relationship; and 3) estimate the target parenteral arginine dose to achieve desirable preterm plasma arginine concentrations.Data SourcesThe PubMed, Scopus, Web of Science, and Cochrane databases were searched regardless of study design; review articles were not included.Data ExtractionOnly articles that discussed amino acid (AA) intake and measured plasma AA profile post PN in VPNs were included. Data were obtained using a data extraction checklist that was devised for the purpose of this review.Data AnalysisTwelve articles met the inclusion criteria. The dose–concentration relationship of arginine content (%) and absolute arginine intake (mg/(kg × d)) with plasma arginine concentrations showed a significant positive correlation (P < 0.001).ConclusionFuture studies using AA solutions with arginine content of 17%–20% and protein intakes of 3.5–4.0 g/kg per day may be needed to achieve higher plasma arginine concentrations.

scholarly journals 129 Early Risk Factors for Retinopathy of Prematurity in Very Preterm Neonates

2019 ◽  
Vol 24 (Supplement_2) ◽  
pp. e50-e51
Author(s):  
Hai-Bo Huang ◽  
Po-Yin Cheung ◽  
Y H Chen ◽  
J Wu ◽  
W Y Lai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Retinopathy Of Prematurity ◽  
Preterm Neonates ◽  
Very Preterm ◽  
Early Risk ◽  
Early Risk Factors
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