scholarly journals Five-country manikin study found that neonatologists preferred using the LISAcath rather than the Angiocath for less invasive surfactant administration

2018 ◽  
Vol 107 (5) ◽  
pp. 780-783 ◽  
Author(s):  
Laura Fabbri ◽  
Katrin Klebermass-Schrehof ◽  
Marta Aguar ◽  
Catherine Harrison ◽  
Ewa Gulczyńska ◽  
...  
Keyword(s):  
Less Invasive ◽  
Manikin Study ◽  
Surfactant Administration

scholarly journals Microbiological analyses of nasally guided catheters after less invasive surfactant administration – a pilot study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Christian A. Maiwald ◽  
Julia Dick ◽  
Matthias Marschal ◽  
Christian Gille ◽  
Axel R. Franz ◽  
...  
Keyword(s):  
Pilot Study ◽  
Less Invasive ◽  
Surfactant Administration ◽  
Microbiological Analyses

Is Less Invasive Surfactant Administration Necessary or “Only” Helpful or Just a Fashion?

2018 ◽  
Vol 35 (06) ◽  
pp. 530-533 ◽  
Author(s):  
Ilia Bresesti ◽  
Laura Fabbri ◽  
Gianluca Lista
Keyword(s):  
Large Scale ◽  
Exogenous Surfactant ◽  
Preterm Neonates ◽  
Positive Pressure ◽  
Less Invasive ◽  
Antenatal Steroids ◽  
Surfactant Replacement Therapy ◽  
Short And Long Term ◽  
Surfactant Administration ◽  
A New Technique

AbstractIn the 1990s, the most relevant pillars in the treatment of neonatal respiratory distress syndrome (RDS) have been improvements in ventilation strategies, the introduction of exogenous surfactant replacement therapy, and the use of antenatal steroids. Lately, in addition to the standard INSURE (INtubation–SURfactant administration–Extubation) method to administer surfactant, a new technique has been gaining increasing popularity. It is the so-called less invasive surfactant administration (LISA) method, which has shown promising results in preventing bronchopulmonary dysplasia development and in reducing mortality in preterm neonates. The rationale behind this technique is to avoid positive pressure ventilation and the endotracheal tube, being surfactant delivered through a thin catheter while the neonate is maintained on continuous positive airway pressure. Given the paucity of large-scale randomized trials on LISA method to prove its effects on short- and long-term outcomes, some questions still remain unanswered. Then, uncertainty regarding the feasibility of this maneuver needs to be better clarified before gaining wide acceptance in routine clinical practice. In our report, we aim at hypothesizing the main mechanisms behind the efficacy of LISA, considering it as a single maneuver in a comprehensive approach for RDS management in the delivery room.

scholarly journals Clinical evaluation of an application aid for less-invasive surfactant administration (LISA)

2020 ◽  
pp. fetalneonatal-2020-319792
Author(s):  
Christian Achim Maiwald ◽  
Patrick Neuberger ◽  
Axel R Franz ◽  
Corinna Engel ◽  
Matthias Vochem ◽  
...  
Keyword(s):  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Median Number ◽  
Neonatal Intensive Care Units ◽  
Open Label ◽  
Catheter Position ◽  
Less Invasive ◽  
Surfactant Administration ◽  
Fraction Of Inspired Oxygen ◽  
Inspired Oxygen

BackgroundLess-invasive surfactant administration (LISA) is increasingly used. We investigated the feasibility of a new LISA-device (Neofact®) in neonates.DesignProspective observational pilot study with open-label LISA in two tertiary neonatal intensive care units.Patients20 infants with a gestational age of ≥26+0/7 weeks and an indication for LISA (Respiratory Severity Score (RSS)≥5 or fraction of inspired oxygen (FiO2) ≥0.30). Infants with respiratory tract malformations or unavailability of an instructed neonatologist were excluded.Main outcome measuresSuccess of LISA, defined as laryngoscopy-confirmed intratracheal catheter position or a decrease in FiO2 by ≥0.05 or to 0.21, accompanied by an RSS decrease of ≥2; number of attempts needed for tracheal catheterisation.Results20/57 screened infants were enrolled. Successful application occurred in 19/20 (95%). One application failed after three attempts. No device-related adverse events occurred. The median number of attempts was 2, success rate per attempt 19/31 (61%).ConclusionLISA via Neofact® appears feasible.

scholarly journals The use of less invasive surfactant administration (LISA) in the United States with review of the literature

2019 ◽  
Vol 39 (3) ◽  
pp. 426-432 ◽  
Author(s):  
Dalibor Kurepa ◽  
Shahana Perveen ◽  
Yisrael Lipener ◽  
Venkatakrishna Kakkilaya
Keyword(s):  
United States ◽  
The United States ◽  
Review Of The Literature ◽  
Less Invasive ◽  
Surfactant Administration

Lung Recruitment and Pendelluft Resolution after Less Invasive Surfactant Administration in a Preterm Infant

2020 ◽  
Vol 202 (5) ◽  
pp. 766-769
Author(s):  
Walusa Assad Gonçalves-Ferri ◽  
Felipe S. Rossi ◽  
Eduardo L. V. Costa ◽  
Letícia Correa ◽  
Daniela Iope ◽  
...  
Keyword(s):  
Preterm Infant ◽  
Lung Recruitment ◽  
Less Invasive ◽  
Surfactant Administration

Survey of less Invasive Surfactant Administration in England, slow adoption and variable practice

2019 ◽  
Vol 109 (3) ◽  
pp. 505-510 ◽  
Author(s):  
Sadaf Bhayat ◽  
Avineet Kaur ◽  
Irnthu Premadeva ◽  
Peter Reynolds ◽  
Harsha Gowda
Keyword(s):  
Less Invasive ◽  
Surfactant Administration ◽  
Variable Practice
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