A workshop report on the development of the Cow's Milk-related Symptom Score awareness tool for young children

2015 ◽  
Vol 104 (4) ◽  
pp. 334-339 ◽  
Author(s):  
Yvan Vandenplas ◽  
Christophe Dupont ◽  
Philippe Eigenmann ◽  
Arne Host ◽  
Mikael Kuitunen ◽  
...  
Keyword(s):  
Young Children ◽  
Symptom Score ◽  
Cow’S Milk ◽  
Workshop Report ◽  
Cow's Milk ◽  
Related Symptom ◽  
Awareness Tool

scholarly journals The Cow’s Milk-Related Symptom Score (CoMiSSTM): Health Care Professional and Parent and Day-to-Day Variability

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 438
Author(s):  
Yvan Vandenplas ◽  
Eva Carvajal ◽  
Stefaan Peeters ◽  
Nadine Balduck ◽  
Yesra Jaddioui ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Professional ◽  
Symptom Score ◽  
Intraclass Correlation ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Related Symptom ◽  
Awareness Tool ◽  
Absolute Agreement ◽  
Rater Variability

The Cow’s Milk-related Symptom Score (CoMiSSTM) was created as an awareness tool for cow’s milk allergy. The aim of the present study was to analyze the inter-rater variability between a pediatrician, parents, and day to day variability. A Health Care Professional (HCP) and parent filled in the CoMiSS independently and blinded for each other to evaluate inter-rater variability. In order to validate day-to-day variability, a parent filled in the CoMiSS during 3 consecutive days and was compared to the CoMiSS scored by the HCP. The absolute agreement between parent and HCP was 75%, and 92.6% and 100% with a tolerance of 0, 1, and 2 points, respectively, resulting in excellent agreement with an intraclass correlation coefficient (ICC) 0.981 (95% Confidence Interval 0.974–0.986, p < 0.001). Day-to-day variability during 3 consecutive days resulted in an absolute agreement of 30%, increasing to 80% and 88.6% when 2 and 3 points, respectively, were accepted. The ICC was excellent for the parental prospective scores (0.93, 95% CI 0.90–0.96; p < 0.001). Day-to-day variability indicates that CoMiSS has a moderate inter-rater reliability. A very low variability was observed when scored prospectively over three days. Data suggest that the CoMiSS can reliably be scored by parents without additional training.

scholarly journals Cow's Milk-related Symptom Score as a predictive tool for cow's milk allergy in Indian children aged 0–24 months

2018 ◽  
Vol 8 (4) ◽  
Author(s):  
Rajniti Prasad ◽  
Ravi Shankar Ayathu Venkata ◽  
Praveen Ghokale ◽  
Pavitra Chakravarty ◽  
Fahmina Anwar
Keyword(s):  
Symptom Score ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Indian Children ◽  
Predictive Tool ◽  
Cow's Milk ◽  
Cow's Milk Allergy ◽  
Related Symptom

scholarly journals Testing the Cow’s Milk-Related Symptom Score (CoMiSSTM) for the Response to a Cow’s Milk-Free Diet in Infants: A Prospective Study

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2402 ◽  
Author(s):  
Silvia Salvatore ◽  
Elisabetta Bertoni ◽  
Federica Bogni ◽  
Valentina Bonaita ◽  
Chiara Armano ◽  
...  
Keyword(s):  
Symptom Score ◽  
Immunoglobulin E ◽  
Gastrointestinal Symptoms ◽  
Cow’S Milk ◽  
P Value ◽  
Cow's Milk ◽  
Related Symptom ◽  
Receiver Operation Characteristic ◽  
Ige Mediated ◽  
A Prospective Study

The diagnosis of cow’s milk allergy (CMA) is particularly challenging in infants, especially with non-Immunoglobulin E (IgE)-mediated manifestations, and inaccurate diagnosis may lead to unnecessary dietary restrictions. The aim of this study was to assess the accuracy of the cow’s milk-related symptom score (CoMiSSTM) in response to a cow’s milk-free diet (CMFD). We prospectively recruited 47 infants (median age three months) who had been placed on a CMFD due to persisting unexplained gastrointestinal symptoms. We compared data with 94 healthy controls (median age three months). The CoMiSSTM score was completed at recruitment and while on the exclusion diet. In 19/47 (40%) cases a response to the diet occurred. At recruitment CoMiSSTM was significantly higher in cases compared to controls (median score 8 vs. 3; p-value: <0.05), 9 cases had a score ≥12 and 8/9 normalized on CMFD. An oral milk challenge was performed in all 19 responders and six of these had a positive reaction to cow’s milk (CM). In eight infants IgE allergy tests were positive. The receiver operation characteristic (ROC) curve identified a CoMISSTM score of 9 to be the best cut-off value (84% sensitivity, 85% specificity, 80% positive (PPV) and 88% negative predictive value (NPV)) for the response to CMFD. We found CoMiSSTM to be a useful tool to help identify infants with persisting gastrointestinal symptoms and suspected CMA that would benefit from CMFD.

scholarly journals Retrospective and Prospective Determination of the Cow's Milk-Related Symptom Score (CoMiSS™) Values in Symptomatic Infants

2021 ◽  
Vol 24 (4) ◽  
pp. 384
Author(s):  
Anna Kozłowska-Jalowska ◽  
Andrea Horvath ◽  
Yvan Vandenplas ◽  
Hania Szajewska
Keyword(s):  
Symptom Score ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Related Symptom

scholarly journals Cow's Milk-Related Symptom Score in Presumed Healthy Polish Infants Aged 0–6 Months

2020 ◽  
Vol 23 (2) ◽  
pp. 154
Author(s):  
Karolina Bigorajska ◽  
Zuzanna Filipiak ◽  
Paulina Winiarska ◽  
Anita Adamiec ◽  
Bogumiła Trent ◽  
...  
Keyword(s):  
Symptom Score ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Related Symptom

scholarly journals Pooled Analysis of the Cow's Milk-related-Symptom-Score (CoMiSS™) as a Predictor for Cow's Milk Related Symptoms

2017 ◽  
Vol 20 (1) ◽  
pp. 22 ◽  
Author(s):  
Yvan Vandenplas ◽  
Philippe Steenhout ◽  
Anette Järvi ◽  
Anne-Sophie Garreau ◽  
Rajat Mukherjee
Keyword(s):  
Symptom Score ◽  
Pooled Analysis ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Related Symptom

scholarly journals Withdrawal: The Cow’s Milk‐related Symptom Score (CoMiSS™): Health care professional and parent and day‐to‐day variability

2020 ◽  
Vol 109 (5) ◽  
pp. 1073-1073
Author(s):  
Eva Carvajal ◽  
Yvan Vandenplas ◽  
Stefaan Peeters ◽  
Nadine Balduck ◽  
Yousra Jaddioui ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Professional ◽  
Symptom Score ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Related Symptom
Sign in / Sign up

Export Citation Format

Share Document