Birth weight and its association with optic nerve head morphology – results from the population‐based German Gutenberg Health Study

2021 ◽  
Author(s):  
Achim Fieß ◽  
Julia Stingl ◽  
Michael S. Urschitz ◽  
Esther M. Hoffmann ◽  
Thomas Münzel ◽  
...  
Keyword(s):  
Birth Weight ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Population Based ◽  
Health Study ◽  
Gutenberg Health Study ◽  
Head Morphology

scholarly journals Birth Weight and Diabetic Retinopathy: Results From the Population-Based Gutenberg Health Study (GHS)

2020 ◽  
pp. 1-9
Author(s):  
Achim Fieß ◽  
Julia Lamparter ◽  
Philipp Raum ◽  
Tunde Peto ◽  
Katharina A. Ponto ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Birth Weight ◽  
Population Based ◽  
Health Study ◽  
Gutenberg Health Study

Association of low birth weight with myopic refractive error and lower visual acuity in adulthood: results from the population-based Gutenberg Health Study (GHS)

2018 ◽  
Vol 103 (1) ◽  
pp. 99-105 ◽  
Author(s):  
Achim Fieß ◽  
Alexander Karl-Georg Schuster ◽  
Stefan Nickels ◽  
Heike M Elflein ◽  
Andreas Schulz ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Birth Weight ◽  
Refractive Error ◽  
Population Based ◽  
Health Study ◽  
Spherical Equivalent ◽  
Gutenberg Health Study ◽  
Corrected Visual Acuity ◽  
Best Corrected Visual Acuity

PurposeLow birth weight (BW) is linked to impaired organ development in childhood, including altered ocular morphological and functional development. The aim of this study was to evaluate whether low BW has long-term effects on visual acuity and refraction in adulthood.MethodsThe Gutenberg Health Study is a population-based, observational cohort study in Germany, including 15 010 participants aged between 35 and 74 years. These participants were divided into three different BW groups (low: <2500 g; normal: between 2500 and 4000 g; and high: >4000 g). Best-corrected visual acuity and objective refraction were examined. We used multivariable linear regression models with adjustment for age, sex, socioeconomic status and self-reported glaucoma, age-related macular degeneration, corneal disease and cataract to assess associations between BW and the main outcome measures, best-corrected visual acuity, spherical equivalent and astigmatism.ResultsOverall, 8369 participants reported their BW. In a multivariable analysis, an association for low BW with spherical equivalent (B=−0.28 per dioptre, P=0.005) and best-corrected visual acuity (B=0.02 logarithm of the minimum angle of resolution, P=0.006) compared with normal BW was observed. For participants with high BW, an association was observed with spherical equivalent (B=0.29 per dioptre, P<0.001), while none with visual acuity.ConclusionsOur data demonstrated that low BW is linked to visual acuity and refractive long-term outcomes long after childhood. Individuals with low BW are more likely to have lower visual acuity and a higher myopic refractive error in adulthood. Adults with high BW are more likely to have a more hyperopic refractive error.

scholarly journals Large-scale machine learning-based phenotyping significantly improves genomic discovery for optic nerve head morphology

2021 ◽  
Author(s):  
Babak Alipanahi ◽  
Farhad Hormozdiari ◽  
Babak Behsaz ◽  
Justin Cosentino ◽  
Zachary R. McCaw ◽  
...  
Keyword(s):  
Machine Learning ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Large Scale ◽  
Head Morphology

scholarly journals A Genetic Epidemiologic Study of Candidate Genes Involved in the Optic Nerve Head Morphology

2012 ◽  
Vol 53 (3) ◽  
pp. 1485 ◽  
Author(s):  
Andrea C. Gasten ◽  
Wishal D. Ramdas ◽  
Linda Broer ◽  
Leonieke M. E. van Koolwijk ◽  
M. Kamran Ikram ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Candidate Genes ◽  
Optic Nerve Head ◽  
Epidemiologic Study ◽  
Head Morphology ◽  
Genetic Epidemiologic Study

Optic nerve head morphology of the Eastern gray squirrel, Sciurus carolinensis

2004 ◽  
Vol 7 (3) ◽  
pp. 169-173
Author(s):  
Lindsay A. Kuester ◽  
Andras M. Komaromy ◽  
Dennis E. Brooks ◽  
Patricia A. Lewis ◽  
Fred Bennett ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Sciurus Carolinensis ◽  
Gray Squirrel ◽  
Head Morphology ◽  
Eastern Gray Squirrel

Abstract 147: The Role of Thrombin Generation in Cardiovascular Disease and Mortality - Results from the Population-based Gutenberg Health Study

2018 ◽  
Vol 38 (Suppl_1) ◽  
Author(s):  
Pauline C van Paridon ◽  
Marina Panova-Noeva ◽  
Rene van Oerle ◽  
Andreas Schulz ◽  
Iris M Hermanns ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Thrombin Generation ◽  
Population Based ◽  
Health Study ◽  
Gutenberg Health Study

scholarly journals Vision-related quality of life considering both eyes: results from the German population-based Gutenberg Health Study (GHS)

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Stefan Nickels ◽  
Alexander K. Schuster ◽  
Heike Elflein ◽  
Christian Wolfram ◽  
Andreas Schulz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Population Based ◽  
Health Study ◽  
German Population ◽  
Gutenberg Health Study ◽  
Related Quality

Atrial Fibrillation Manifestations Risk Factors and Sex Differences in a Population-Based Cohort (From the Gutenberg Health Study)

2018 ◽  
Vol 122 (1) ◽  
pp. 76-82 ◽  
Author(s):  
Christina Magnussen ◽  
Francisco M. Ojeda ◽  
Philipp S. Wild ◽  
Nils Sörensen ◽  
Thomas Rostock ◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Sex Differences ◽  
Population Based ◽  
Health Study ◽  
Gutenberg Health Study
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