scholarly journals Clinical benefits and potential risks of adalimumab in non‐JIA chronic paediatric uveitis

2021 ◽  
Author(s):  
Carlyn V. Kouwenberg ◽  
Viera Koopman‐Kalinina Ayuso ◽  
Joke H. de Boer
Author(s):  
Sean Swearingen ◽  
Kim Allan Williams Sr

Despite extensive research demonstrating the clinical benefits of exercise, the possibility of adverse effects from high intensity exercise causes patients to shy away from achieving the full cardiac benefits of physical activity. Although it is possible for high intensity exercise to lead to cardiac complications, for the average American the benefits far outweigh the risks. By understanding the possible pathology that can develop with high intensity exercise, and evaluating who is truly at risk for harmful events related to intense exercise, most individuals can return to their physical activity of choice with the knowledge that they are improving their health and are at minimal risk of self-harm.


Cephalalgia ◽  
2008 ◽  
Vol 28 (2_suppl) ◽  
pp. 28-35 ◽  
Author(s):  
A Gendolla

Over the last 10 years, triptans (serotonin 5-HT1B/1D receptor agonists) have proved to be efficacious in treating migraine pain. However, recent evidence suggests that patients are still not receiving optimal pain management, particularly in clinical trials, where triptan treatment is generally not initiated until pain has reached moderate intensity. Pathophysiological evidence indicates that if treatment is initiated at an early stage, while pain is still mild and before the onset of central sensitization, outcomes for patients may be improved. In addition, a small number of clinical trials have been reported in which triptans were taken early (within 1 h of pain onset) or while pain was still mild; although constraints of trial design and data analysis limit definite conclusions, overall the results suggest that this early/mild approach results in more rapid and sustained pain relief. New studies are therefore needed to clarify the clinical benefits of early treatment, whilst taking into account potential risks, such as medication overuse. Ultimately, migraine treatment strategies require optimization in order to meet patient expectations and to reduce the current burden of migraine-associated disability.


2014 ◽  
Vol 21 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Helen Pryce ◽  
Amanda Hall

Shared decision-making (SDM), a component of patient-centered care, is the process in which the clinician and patient both participate in decision-making about treatment; information is shared between the parties and both agree with the decision. Shared decision-making is appropriate for health care conditions in which there is more than one evidence-based treatment or management option that have different benefits and risks. The patient's involvement ensures that the decisions regarding treatment are sensitive to the patient's values and preferences. Audiologic rehabilitation requires substantial behavior changes on the part of patients and includes benefits to their communication as well as compromises and potential risks. This article identifies the importance of shared decision-making in audiologic rehabilitation and the changes required to implement it effectively.


2007 ◽  
Vol 177 (4S) ◽  
pp. 26-27
Author(s):  
Dennis H. Kim ◽  
Jocelyn M. Rieder ◽  
Eugene Y. Rhee ◽  
Shawn A. Menefee ◽  
Michael H. Ree ◽  
...  

2011 ◽  
Vol 42 (4) ◽  
pp. 32
Author(s):  
ELIZABETH MECHCATIE
Keyword(s):  

2020 ◽  
pp. 7-9

Examination of (35) samples of spices obtained from local markets for the purposes of isolating and diagnosing fungi growing on them. Anine isolates belonging to 13 different types of fungi were diagnosed by the standard dilution method with three replications, and it has been observed that the most samples from which the fungi were isolated is ginger. It was found that the most isolated species of fungi are Penicillium, Aspergillus, and Rizupes spp. A rare colony of fungi was observed, which indicates contamination of the spices under study with the fungus. The present study aims to identify the potential risks of the presence of fungi in spices and what may result from mycotoxins that may be the cause of many chronic diseases as a result of using these spices in large quantities. The study recommends limiting the use of contaminated spices, especially ginger, in preparing food and its uses, in addition to other types such as cloves, black and white pepper, and other types of spices found in the local markets, especially the expired ones.


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