Influence of time to procurement, incubation and release of organ cultured donor corneas on graft failure after Descemet Stripping Automated Endothelial Keratoplasty

2021 ◽  
Author(s):  
Niels Gram ◽  
Anders Shehab ◽  
Anders Ivarsen ◽  
Jesper Hjortdal
Keyword(s):  
Graft Failure ◽  
Endothelial Keratoplasty ◽  
Donor Corneas

Descemet Membrane Endothelial Keratoplasty as Treatment for Graft Failure After Descemet Stripping Automated Endothelial Keratoplasty

2015 ◽  
Vol 159 (6) ◽  
pp. 1050-1057.e2 ◽  
Author(s):  
Julia M. Weller ◽  
Theofilos Tourtas ◽  
Friedrich E. Kruse ◽  
Ursula Schlötzer-Schrehardt ◽  
Thomas Fuchsluger ◽  
...  
Keyword(s):  
Graft Failure ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane

Endothelial Keratoplasty: The Influence of Preoperative Donor Endothelial Cell Densities on Dislocation, Primary Graft Failure, and 1-Year Cell Counts

Cornea ◽  
2008 ◽  
Vol 27 (10) ◽  
pp. 1131-1137 ◽  
Author(s):  
Mark A Terry ◽  
Neda Shamie ◽  
Edwin S Chen ◽  
Karen L Hoar ◽  
Paul M Phillips ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Graft Failure ◽  
Endothelial Keratoplasty ◽  
Cell Counts ◽  
Primary Graft Failure ◽  
Cell Densities

scholarly journals Clinical Outcomes of Penetrating Keratoplasty and Descemet Stripping Automated Endothelial Keratoplasty in Asian Population with American Corneas

2019 ◽  
Vol 16 (22) ◽  
pp. 4547 ◽  
Author(s):  
Hsiao ◽  
Chen ◽  
Meir ◽  
Tan ◽  
Hsiao ◽  
...  
Keyword(s):  
Survival Rate ◽  
Graft Survival ◽  
Penetrating Keratoplasty ◽  
Survival Rates ◽  
Asian Population ◽  
Chang Gung Memorial Hospital ◽  
Endothelial Keratoplasty ◽  
Significant Difference ◽  
Donor Corneas

To determine the comparative efficacy and safety of penetrating keratoplasty (PK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in the Asian population receiving imported donor corneas, our single-center retrospective study provides analysis supporting the transition from PK to DSAEK in the Asian population using imported American donor corneas. We analyzed 259 patients with 241 and 57 cases of PK and DSAEK respectively during 2008 to 2017 using imported corneas at Chang Gung Memorial Hospital, Linkou, Taiwan. In terms of long-term graft survival analysis, there was no difference between PK and DSAEK (log-rank p = 0.386, HR = 0.920, 95% CI: [0.641–1.380]). However, Cox proportional regression analysis revealed that corneal survival rate of DSAEK group in the first 100 days after transplantation was inferior than that of PK group (log-rank p < 0.001, HR = 2.733, 95% CI: [1.501–4.977])]. Despite the inferior survival rate, there were significantly less neovascularization and Descemet membrane folds in the DSAEK group. Importantly, the non-complication rate of DSAEK was much higher than that of PK with significant difference (PK, 25.7% vs DSAEK 42.0%, p = 0.022). Collectively, DSAEK is suggested as an alternative surgical modality in Asian patients using imported American donor corneas because of less complication, and no difference in long-term corneal graft survival rates between PK and DSAEK.

scholarly journals Ultrastructural findings in graft failure after Descemet membrane endothelial keratoplasty (DMEK) and new triple procedure

Medicine ◽  
2019 ◽  
Vol 98 (19) ◽  
pp. e15493 ◽  
Author(s):  
Isabell Schmidt ◽  
Ursula Schlötzer-Schrehardt ◽  
Achim Langenbucher ◽  
Timo Eppig ◽  
Tobias Hager ◽  
...  
Keyword(s):  
Graft Failure ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane ◽  
Triple Procedure ◽  
Ultrastructural Findings

scholarly journals Outcomes of Resident-Performed Descemet's Stripping Automated Endothelial Keratoplasty

2017 ◽  
Vol 09 (01) ◽  
pp. e26-e31
Author(s):  
Tatyana Beketova ◽  
Margaret Pfeiffer ◽  
Alice Chuang ◽  
Gene Kim
Keyword(s):  
Graft Failure ◽  
Glaucoma Patient ◽  
Case Series ◽  
Glaucoma Surgery ◽  
Bullous Keratopathy ◽  
Endothelial Keratoplasty ◽  
Ocular Surgery ◽  
Pseudophakic Bullous Keratopathy ◽  
Primary Graft Failure

Purpose This article aimed to evaluate outcomes of resident-performed Descemet's stripping automated endothelial keratoplasty (DSAEK). Methods This is a case series of patients who underwent DSAEK performed by PGY-4 ophthalmology residents at Lyndon B. Johnson Hospital from January 2013 to August 2016 staffed by a fellowship-trained cornea specialist. Patients with less than 1 month of follow-up were excluded. Demographics, baseline ocular characteristics, and intraoperative data were recorded. Vision and graft status were recorded at 1 week, 1 month, 3 months, and the last follow-up visits. Surgical failure was defined as graft detachment within 1 week of surgery and/or primary graft failure within 3 months of surgery. Results Eighteen eyes of 18 patients who followed up for 14.9 months (±12.9) were included. Mean age of patients was 60.9 years (±13.2). Indications for DSAEK included pseudophakic bullous keratopathy (10), Fuchs endothelial dystrophy (4), and other causes of endothelial dysfunction (4). Eleven (61%) eyes had prior ocular surgery, and 7 (39%) had prior glaucoma surgery. There were no postoperative graft detachments and two (11%) primary graft failures. There was one primary graft failure in a glaucoma patient. Of the 16 graft successes, logMAR visual acuity improved by 0.46 logMAR (±0.73) from baseline. Conclusion With appropriate staffing by an experienced cornea surgeon, DSAEK with residents as the primary surgeons is a safe and effective procedure with reasonably good outcomes.

Pre-Descemet Endothelial Keratoplasty With Infant Donor Corneas

Cornea ◽  
2015 ◽  
Vol 34 (8) ◽  
pp. 859-865 ◽  
Author(s):  
Ashvin Agarwal ◽  
Amar Agarwal ◽  
Priya Narang ◽  
Dhivya A. Kumar ◽  
Soosan Jacob
Keyword(s):  
Endothelial Keratoplasty ◽  
Donor Corneas
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