Microvascular alterations detected by optical coherence tomography angiography in non‐arteritic anterior ischaemic optic neuropathy: a meta‐analysis

2021 ◽  
Author(s):  
Yuyu Chou ◽  
Bilei Zhang ◽  
Jin Ma ◽  
Yong Zhong
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Neuropathy ◽  
Optical Coherence Tomography Angiography ◽  
Meta Analysis ◽  
Optical Coherence ◽  
Ischaemic Optic Neuropathy ◽  
Anterior Ischaemic Optic Neuropathy ◽  
Microvascular Alterations

scholarly journals Choroidal Thickness in Nonarteritic Anterior Ischaemic Optic Neuropathy: A Study with Optical Coherence Tomography

2014 ◽  
Vol 38 (4) ◽  
pp. 173-179 ◽  
Author(s):  
Arnaldo Dias-Santos ◽  
Joana Ferreira ◽  
Luís Abegão Pinto ◽  
André Vicente ◽  
Rita Anjos ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Neuropathy ◽  
Choroidal Thickness ◽  
Optical Coherence ◽  
Ischaemic Optic Neuropathy ◽  
Anterior Ischaemic Optic Neuropathy

scholarly journals Optical Coherence Tomography Angiography Assessment of the Peripapillary Vessel Density and Structure in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy: A Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Ling Ling ◽  
Kaibao Ji ◽  
Liping Xie ◽  
Feifei Gao ◽  
Qinglin Zhang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Neuropathy ◽  
Optical Coherence Tomography Angiography ◽  
Meta Analysis ◽  
Vessel Density ◽  
Anterior Ischemic Optic Neuropathy ◽  
Cochrane Library ◽  
Ischemic Optic Neuropathy ◽  
Optical Coherence ◽  
Rnfl Thickness

Background. This meta-analysis is aimed at assessing the peripapillary vessel density (VD) and structural outcomes using optical coherence tomography angiography (OCTA) in patients with nonarteritic anterior ischemic optic neuropathy (NAION). Methods. A comprehensive search of PubMed, Embase, Cochrane Library, and Web of Science databases for literature comparing VD and structural outcomes in patients with NAION and controls was performed. Mean differences (MDs) and its 95% confidence interval (CI) were calculated for continuous estimates. Review Manager (V5.30) was used for analysis. Results. Fourteen published studies met the requirement. The radial peripapillary capillary (RPC) whole enface VD measured by OCTA was significantly lower in patients with NAION compared to that of the controls ( MD = − 10.51 , P < 0.00001 ). The RPC inside disc VD was significantly decreased in the NAION group than that in the control group ( MD = − 8.47 , P < 0.00001 ). For RPC peripapillary VD, there was a statistically significant difference between patients with NAION and the controls ( MD = − 12.48 , P < 0.00001 ). The peripapillary retinal nerve fibre layer (p-RNFL) thickness was significantly lower in patients with NAION in comparison to the controls ( MD = − 22.18 , P = 0.004 ). The ganglion cell complex (GCC) thickness in the macular zone of NAION patients was remarkably reduced compared to that in the controls ( MD = − 17.18 , P = 0.0002 ). Conclusions. The findings suggested that the peripapillary VD and RNFL thickness were attenuated, and the macular GCC thickness was reduced in patients with NAION. OCTA, in the future, may facilitate the diagnosis and monitoring of patients with NAION.

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