scholarly journals Prescription pattern of ocular hypotensive drugs in Portugal and its comparison with the European guidelines – PEM Study

2019 ◽  
Vol 97 (7) ◽  
Author(s):  
Gonçalo Pimenta ◽  
David Cordeiro Sousa ◽  
Inês Leal ◽  
Carlos Marques‐Neves ◽  
Luís Abegão Pinto
Keyword(s):  
Prescription Pattern ◽  
European Guidelines ◽  
Hypotensive Drugs

scholarly journals Prescription pattern of ocular hypotensive drugs in Portugal and its comparison with the European guidelines - PEM study

2017 ◽  
Vol 95 ◽  
Author(s):  
G. Pimenta ◽  
D.C. Sousa ◽  
I. Leal ◽  
C. Marques-Neves ◽  
L. Abegão Pinto
Keyword(s):  
Prescription Pattern ◽  
European Guidelines ◽  
Hypotensive Drugs

Transitioning towards official clinical guidelines for the diagnostics and treatment of severe behavioural problems in children across Europe: current state and future directions.

2017 ◽  
Author(s):  
Alexandra-Raluca Gatej ◽  
Audri Lamers ◽  
Robert Vermeiren ◽  
Lieke van Domburgh
Keyword(s):  
Mental Health ◽  
Clinical Guidelines ◽  
Clinical Decision Making ◽  
Daily Practice ◽  
Clinical Decision ◽  
European Guidelines ◽  
Current State ◽  
Assessment And Treatment ◽  
Evidence Based Treatments ◽  
Multifactorial Approach

Severe behaviour problems (SBPs) in early childhood include oppositional and aggressive behaviours and predict negative mental health outcomes later in life. Although effective treatments for this group are available and numerous clinical practice guidelines have been developed to facilitate the incorporation of evidence-based treatments in clinical decision-making (NICE, 2013), many children with SBPs remain unresponsive to treatment (Lahey & Waldman, 2012). At present, it is unknown how many countries in Europe possess official clinical guidelines for SBPs diagnosis and treatment and what is their perceived utility. The aim was to create an inventory of clinical guidelines (and associated critical needs) for the diagnostics and treatment of SBPs in youth mental health across Europe according to academic experts and mental health clinicians’ opinions. To investigate the aim, two separate online semi-structured questionnaires were used, one directed at academics (N=28 academic experts; 23 countries), and the other at clinicians (N=124 clinicians; 24 countries). Three key results were highlighted. First, guidelines for SBPs are perceived as beneficial by both experts and clinicians. However, their implementation needs to be reinforced and content better adapted to daily practice. Improvements may include taking a multifactorial approach to assessment and treatment, involving the systems around the child, and multidisciplinary collaboration. Second, academic experts and clinicians support the need for further developing national / European guidelines. Finally, future guidelines should address current challenges identified by clinicians to be more applicable to daily practice.

Analysis of Chinese herbal formulae recommended for COVID-19 in different schemes in China: A data mining Approach

2020 ◽  
Vol 23 ◽  
Author(s):  
LiWei Yin ◽  
YaCen Gao ◽  
ZiPing Li ◽  
MengYu Wang ◽  
KaiXin Chen
Keyword(s):  
Data Mining ◽  
Early Stage ◽  
Herbal Medicines ◽  
Chinese Herbs ◽  
Recovery Stage ◽  
Prescription Pattern ◽  
Middle Stage ◽  
Chinese Herbal ◽  
Severe Stage ◽  
Herbal Formulae

Background: Novel coronavirus pneumonia (NCP), or coronavirus disease 2019 (COVID-19), is a worldwide health threat that has affected millions of people globally. Traditional Chinese medicine (TCM) has been introduced for the treatment of COVID-19. However, efficacy differs among herbal medicines, and the ideal prescription pattern for TCM herbal formulae for COVID-19 treatment needs to be explored. Therefore, the data mining method has been used in this study to analyze the TCM prescription pattern for COVID-19. Objective: The aim of this study was to analyze the TCM prescription pattern in Regional Schemes in China for COVID-19 in order to provide a new reference for the use of TCM in COVID-19 treatment. Method: By searching the TCM treatment protocols of COVID-19 in 23 Regional Schemes, TCM syndromes and herbal medicines were analyzed by data mining. The Ancient and Modern Medical Case Cloud Platform (V2.1 personal Edition) was used to perform frequency statistics, correlation analysis, and cluster analysis. A total of 82 TCM syndromes and 171 Chinese herbal medicines were found. The course of the disease can be divided into the early stage, middle stage, severe stage, and recovery stage. Results: In the early stage, the focus is primarily on resolving dampness, dispelling cold, and diffusing the lungs. In the middle stage, the treatment priority is clearing heat and resolving toxins, promoting lung function, and relieving asthma. In the severe stage, the focus is on tonifying Qi, restoring Yang, and relieving depletion of Yin and Yang. In the recovery stage, the main treatment is to invigorate the spleen and regulate Qi, tonify Qi, nourish Yin, and clear residual disease evil. There are certain differences between the Regional Schemes and the Nation Schemes, but the core prescription pattern of the former is consistent with the latter. The effectiveness of these 171 Chinese herbs include but are not limited to inhibiting COVID-19, strengthening immune system function, preventing heart failure, acting as antioxidants, oxidative stress inhibitory effects, maintaining organ function, and improving leukocyte survival. Conclusion: This study may help to improve understanding of TCM herbal prescription pattern, practices, reveal the efficacy of combinations of Chinese herbs, and provide new ideas for TCM treatment for COVID-19.

scholarly journals Transposition of European Guidelines for Energy Communities into Austrian Law: A Comparison and Discussion of Issues and Positive Aspects

Energies ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3922
Author(s):  
Bernadette Fina ◽  
Hubert Fechner
Keyword(s):  
Renewable Energy ◽  
Electricity Market ◽  
Clean Energy ◽  
Detailed Comparison ◽  
Regulatory Framework ◽  
Policy Makers ◽  
European Guidelines ◽  
Subsequent Discussion ◽  
Grid Operators ◽  
Austrian Law

The Renewable Energy Directive and the Electricity Market Directive, both parts of the Clean Energy for all Europeans Package (issued in 2019), provide supranational rules for renewable energy communities and citizen energy communities. Since national transpositions need to be completed within two years, Austria has already drafted corresponding legislation. This article aims at providing a detailed comparison of the European guidelines and the transposition into Austrian law. The comparison not only shows how, and to what extent, the European guidelines are transposed into Austrian law, but also helps to identify loopholes and barriers. The subsequent discussion of these issues as well as positive aspects of the Austrian transposition may be advantageous for legislators and policy makers worldwide in their process of designing a coherent regulatory framework. It is concluded that experts from different areas (i.e., project developers, scientists concerned with energy communities, energy suppliers and grid operators) should be closely involved in the law-making process in order to introduce different perspectives so that a consistent and supportive regulatory framework for energy communities is created.

An Empirical Study on the Operative Treatment of Symptomatic Urolithiasis in Germany

2021 ◽  
pp. 1-7
Author(s):  
Alina Reicherz ◽  
Rüveyde Sahin ◽  
Lorine Häuser ◽  
Joachim Noldus ◽  
Peter Bach
Keyword(s):  
Response Rate ◽  
Intraoperative Complications ◽  
Nationwide Survey ◽  
Treatment Modalities ◽  
European Guidelines ◽  
Operative Care ◽  
Double J Stent ◽  
Before And After ◽  
Related Group ◽  
Ureteral Stenting

<b><i>Purpose:</i></b> The guidelines of the German, European, and American Urological Associations on urolithiasis advise against general ureteral stenting before and after an uncomplicated ureterorenoscopy (URS). However, German and European guidelines state that stenting prior to URS facilitates stone extraction and reduces intraoperative complications. According to the published literature, German practice seems to deviate from recommendations. This nationwide survey aimed to evaluate the treatment modalities of urolithiasis. <b><i>Methods:</i></b> In November 2018 and March 2019, a total of 199 urological hospital departments in Germany were anonymously surveyed about operative care of symptomatic urolithiasis. The response rate was 72.9%. The survey consisted of 25 questions about diagnostics, surgical technique, and aftercare of the URS. This questionnaire is available in the appendix. <b><i>Results:</i></b> A primary URS is performed in ≤10% in 49.6% of the hospitals. In every second urological department (49.7%), the German Diagnosis Related Group (G-DRG) system influences the period of pre-stenting before a secondary URS. After a secondary URS, which is performed in 53.8% of the departments in over 80% of the patients, 14% of the departments omit stenting. The standard for stenting seems to be a 28-cm-long 7 Charrière double-J stent in Germany. <b><i>Conclusion:</i></b> In Germany, the percentage of primary URS is low, and a ureter stenting is performed in most of the urological departments after URS. Delaying therapy due to economic aspects is the standard in almost half of all urological departments.

scholarly journals Accuracy of upper endoscopies with random biopsies to identify patients with gastric premalignant lesions who can safely be exempt from surveillance

2021 ◽  
Vol 24 (3) ◽  
pp. 680-690
Author(s):  
Michiel C. Mommersteeg ◽  
Stella A. V. Nieuwenburg ◽  
Wouter J. den Hollander ◽  
Lisanne Holster ◽  
Caroline M. den Hoed ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
High Risk ◽  
Low Risk ◽  
Premalignant Lesions ◽  
High Risk Patients ◽  
European Guidelines ◽  
Progression Of Disease ◽  
Risk Patients ◽  
Progression Risk

Abstract Introduction Guidelines recommend endoscopy with biopsies to stratify patients with gastric premalignant lesions (GPL) to high and low progression risk. High-risk patients are recommended to undergo surveillance. We aimed to assess the accuracy of guideline recommendations to identify low-risk patients, who can safely be discharged from surveillance. Methods This study includes patients with GPL. Patients underwent at least two endoscopies with an interval of 1–6 years. Patients were defined ‘low risk’ if they fulfilled requirements for discharge, and ‘high risk’ if they fulfilled requirements for surveillance, according to European guidelines (MAPS-2012, updated MAPS-2019, BSG). Patients defined ‘low risk’ with progression of disease during follow-up (FU) were considered ‘misclassified’ as low risk. Results 334 patients (median age 60 years IQR11; 48.7% male) were included and followed for a median of 48 months. At baseline, 181/334 (54%) patients were defined low risk. Of these, 32.6% were ‘misclassified’, showing progression of disease during FU. If MAPS-2019 were followed, 169/334 (51%) patients were defined low risk, of which 32.5% were ‘misclassified’. If BSG were followed, 174/334 (51%) patients were defined low risk, of which 32.2% were ‘misclassified’. Seven patients developed gastric cancer (GC) or dysplasia, four patients were ‘misclassified’ based on MAPS-2012 and three on MAPS-2019 and BSG. By performing one additional endoscopy 72.9% (95% CI 62.4–83.3) of high-risk patients and all patients who developed GC or dysplasia were identified. Conclusion One-third of patients that would have been discharged from GC surveillance, appeared to be ‘misclassified’ as low risk. One additional endoscopy will reduce this risk by 70%.

Sign in / Sign up

Export Citation Format

Share Document