Heterogeneity in arterial hypertension and ocular perfusion pressure definitions: Towards a consensus on blood pressure‐related parameters for glaucoma studies

2018 ◽  
Vol 97 (4) ◽  
pp. e487-e492 ◽  
Author(s):  
João Barbosa‐Breda ◽  
Luis Abegão‐Pinto ◽  
Karel Van Keer ◽  
Danilo A. Jesus ◽  
Sophie Lemmens ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Perfusion Pressure ◽  
Ocular Perfusion Pressure ◽  
Ocular Perfusion

scholarly journals Blood Pressure, Ocular Perfusion Pressure, and Body Mass Index in Glaucoma Patients

2013 ◽  
Vol 23 (5) ◽  
pp. 664-669 ◽  
Author(s):  
Sandra Ngo ◽  
Alon Harris ◽  
Brent A. Siesky ◽  
Anne Schroeder ◽  
George Eckert ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Perfusion Pressure ◽  
Ocular Perfusion Pressure ◽  
Ocular Perfusion

Inter-relationship between ocular perfusion pressure, blood pressure, intraocular pressure profiles and primary open-angle glaucoma: the Singapore Epidemiology of Eye Diseases study

2018 ◽  
Vol 102 (10) ◽  
pp. 1402-1406 ◽  
Author(s):  
Yih-Chung Tham ◽  
Sing-Hui Lim ◽  
Preeti Gupta ◽  
Tin Aung ◽  
Tien Y Wong ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Perfusion Pressure ◽  
Open Angle Glaucoma ◽  
Eye Diseases ◽  
Open Angle ◽  
Ocular Perfusion Pressure ◽  
Ocular Perfusion ◽  
Relevant Covariates

ObjectiveTo elucidate the inter-relationship between ocular perfusion pressure (OPP), blood pressure (BP), intraocular pressure (IOP) profiles and primary open-angle glaucoma (POAG) in a multiethnic Asian population.MethodsParticipants were recruited from the Singapore Epidemiology of Eye Diseases Study and underwent standardised ocular and systemic examinations. POAG was defined according to the International Society for Geographical and Epidemiological Ophthalmology criteria. Logistic regression analyses with generalised estimating equation models were performed and used to account for correlation between eyes.ResultsA total of 9877 participants (19 587 eyes), including 213 POAG cases (293 eyes) were included. Eyes with lowest quartile levels of systolic OPP (SOPP <110 mm Hg) were 1.85 times (95% CI 1.16 to 2.95) likely to have POAG, compared with eyes with mid-range SOPP levels (123–137 mm Hg; third quartile), after adjusting for relevant covariates and IOP. Consistently, we found that lowest quartile of systolic BP (SBP <124 mm Hg) was 1.69 times (95% CI 1.08 to 2.66) likely to have POAG, compared with mid-range SBP levels (138–153 mm Hg; third quartile). Furthermore, the effect of lower SBP on POAG was more pronounced in eyes with IOP ≥21 mm Hg (OR 3.90; 95% CI 1.24 to 12.30). Both the mean and diastolic profiles of OPP and BP were not significantly associated with POAG, after adjusting for relevant covariates and IOP.ConclusionsIn this population-based sample of nearly 10 000 Asian individuals, we showed that low SOPP was associated with POAG. This association was potentially in part secondary to low SBP and high IOP. Our findings provide further clarity on the roles of OPP surrogates and BP profiles in POAG.

scholarly journals The Relationship between Low Ocular Perfusion Pressure with Acute Non-Arterial Anterior Ischemic Optic Neuropathy

2020 ◽  
Author(s):  
Xiaotang Wang ◽  
Runsheng Wang ◽  
Ying Wang ◽  
Xu Wang
Keyword(s):  
Blood Pressure ◽  
Optic Neuropathy ◽  
Statistical Difference ◽  
Perfusion Pressure ◽  
Blood Perfusion ◽  
Anterior Ischemic Optic Neuropathy ◽  
Ischemic Optic Neuropathy ◽  
Ocular Perfusion Pressure ◽  
Ocular Perfusion ◽  
The Relationship

Abstract Objective: To investigate the relationship between low ocular perfusion pressure (OPP) with acute non-arterial anterior ischemic optic neuropathy (ANAION).Methods: Forty- six patients (46 eyes) with ANAION from July 2010 to December 2016 were retrospectively analyzed. The 24-h intraocualr pressure (IOP) in sitting position was measured by non-contact tonometer. The brachial artery systolic blood pressure (SBP) and diastolic blood pressure (DBP) were simultaneously measured by electrocardiogram monitor. The 24-h OPP was calculated according to the measured blood pressure and intraocular pressure: OPP= 45% DBP-IOP. OPP< 10mmHg was defined as low OPP. Sudden visual acuity declining or visual field defect was recorded as the attack of ANAION. 24h was divided into four periods: period A (1-6 A.M), period B (6-12 A.M), period C (12-18 P.M) and period D (18-24 P.M). The correlation between low OPP and ANAION was analyzed. Statistical method was used by Person correlation analysis.Results: There was a statistical difference in the low OPP in the four periods (P< 0.05). The most common period of low OPP was period A (1-6 A.M), with the incidence of low OPP as high as 58.3%. There was a statistical difference in the incidence of ANAION in the four periods (P< 0.05). Most common time period of ANAION was also period A (1-6 A.M), with the incidence rate as high as 46.3%. Person correlation analysis showed that the period of low OPP was associated with the period of ANAION onset (r=0.934, P < 0.05).Conclusion: There was a significant clinical correlation between low OPP and ANAION. Period A (1-6 A.M) was the high-risk period for low OPP and ANAION. The occurrence of ANAION can be reduced by elevating the OPP to improve the blood perfusion of the anterior optic nerve.

Sign in / Sign up

Export Citation Format

Share Document