scholarly journals Objective and subjective outcomes of strabismus surgery in Graves' orbitopathy: a prospective multicentre study

2017 ◽  
Vol 95 (4) ◽  
pp. 386-391 ◽  
Author(s):  
Hinke Marijke Jellema ◽  
Peerooz Saeed ◽  
Ilse Mombaerts ◽  
Peter J. Dolman ◽  
Jim Garrity ◽  
...  
Keyword(s):  
Multicentre Study ◽  
Strabismus Surgery ◽  
Prospective Multicentre Study ◽  
Graves Orbitopathy ◽  
Subjective Outcomes

scholarly journals Geriatric fracture centre vs usual care after proximal femur fracture in older patients: what are the benefits? Results of a large international prospective multicentre study

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e039960
Author(s):  
Michael Blauth ◽  
Alexander Joeris ◽  
Elke Rometsch ◽  
Kathrin Espinoza-Rebmann ◽  
Pannida Wattanapanom ◽  
...  
Keyword(s):  
Adverse Events ◽  
Multicentre Study ◽  
Usual Care ◽  
Proximal Femur ◽  
Interdisciplinary Treatment ◽  
Proximal Femur Fracture ◽  
Geriatric Fracture ◽  
Femur Fractures ◽  
Prospective Multicentre Study ◽  
Registration Number

ObjectiveThe aim of this study was to determine the effect of treatment in geriatric fracture centres (GFC) on the incidence of major adverse events (MAEs) in patients with hip fractures compared with usual care centres (UCC). Secondary objectives included hospital-workflow and mobility-related outcomes.DesignCohort study recruiting patients between June 2015 and January 2017. Follow-up was 1 year.SettingInternational (six countries, three continents) multicentre study.Participants281 patients aged ≥70 with operatively treated proximal femur fractures.InterventionsTreatment in UCCs (n=139) or GFCs (n=142), that is, interdisciplinary treatment including regular geriatric consultation and daily physiotherapy.Outcome measuresPrimary outcome was occurrence of prespecified MAEs, including delirium. Secondary outcomes included any other adverse events, time to surgery, time in acute ward, 1-year mortality, mobility, and quality of life.ResultsPatients treated in GFCs (n=142) had a mean age of 81.9 (SD, 6.6) years versus 83.9 (SD 6.9) years in patients (n=139) treated in UCCs (p=0.013) and a higher mean Charlson Comorbidity Index of 2.0 (SD, 2.1) versus 1.2 (SD, 1.5) in UCCs (p=0.001). More patients in GFCs (28.2%) experienced an MAE during the first year after surgery compared with UCCs (7.9%) with an OR of 4.56 (95% CI 2.23 to 9.34, p<0.001). Analysing individual MAEs, this was significant for pneumonia (GFC: 9.2%; UCC: 2.9%; OR, 3.40 (95% CI 1.08 to 10.70), p=0.027) and delirium (GFC: 11.3%; UCC: 2.2%, OR, 5.76 (95% CI 1.64 to 20.23), p=0.002).ConclusionsContrary to our study hypothesis, the rate of MAEs was higher in GFCs than in UCCs. Delirium was revealed as a main contributor. Most likely, this was based on improved detection rather than a truly elevated incidence, which we interpret as positive effect of geriatric comanagement.Trial registration numberClinicalTrials.gov: NCT02297581.

Safety and tolerability of dobutamine-atropine stress echocardiography: a prospective, multicentre study

The Lancet ◽  
1994 ◽  
Vol 344 (8931) ◽  
pp. 1190-1192 ◽  
Author(s):  
E Picano ◽  
W Mathias ◽  
Pingitore A ◽  
Bigi R ◽  
Previtali M
Keyword(s):  
Multicentre Study ◽  
Stress Echocardiography ◽  
Prospective Multicentre Study

Early loading of mandibular full-arch bridges screw retained after 1 week to four to five Monotype®implants: 3-year results from a prospective multicentre study

2008 ◽  
Vol 19 (7) ◽  
pp. 693-703 ◽  
Author(s):  
Kristina Arvidson ◽  
Ove Esselin ◽  
Ewa Felle-Persson ◽  
Goran Jonsson ◽  
Jan-Ivan Smedberg ◽  
...  
Keyword(s):  
Multicentre Study ◽  
Prospective Multicentre Study ◽  
Early Loading ◽  
Arch Bridges
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