scholarly journals Carbon fiducials for large choroidal melanoma treated with gamma knife radiosurgery

2016 ◽  
Vol 94 (8) ◽  
pp. e806-e807 ◽  
Author(s):  
Margaret M. Reynolds ◽  
Thomas J. Whitaker ◽  
Ian F. Parney ◽  
Timothy F. Kozelsky ◽  
Yolanda I. Garces ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Choroidal Melanoma

scholarly journals 3D WrapTM Ultra-Widefield Reconstruction in Stereotactic Radiosurgery for Choroidal Melanoma

2019 ◽  
Vol 6 (1) ◽  
pp. 20-24
Author(s):  
Maria Vittoria Cicinelli ◽  
Alessandro Marchese ◽  
Francesco Bandello ◽  
Giulio Maria Modorati
Keyword(s):  
Side Effects ◽  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Three Dimensional ◽  
Choroidal Melanoma ◽  
Ocular Complications ◽  
Virtual Reconstruction ◽  
Radiation Induced ◽  
Imaging Instrument

Choroidal melanoma (CM) is the most commonly diagnosed primary intraocular malignancy in adults. Gamma knife radiosurgery (GKR) has demonstrated reliable results in the treatment of CM, but it is limited by the risk of radiation-induced ocular complications. To optimize the dose of radiation focused on the tumor, and limit side effects, the eye should be properly immobilized before treatment. A recently released ultra-widefield imaging instrument (Optomap California; Optos, Dunfermline, Scotland, UK) allows for an interactive three-dimensional (3D) virtual reconstruction of the globe, called 3D WrapTM. The authors share their experience with this rapid, reliable, and relatively easy support in planning globe positioning before GKR treatment.

Dose De-Escalation With Gamma Knife Radiosurgery in the Treatment of Choroidal Melanoma

2009 ◽  
Vol 75 (1) ◽  
pp. 170-176 ◽  
Author(s):  
Clemens M. Schirmer ◽  
Michael Chan ◽  
John Mignano ◽  
Jay Duker ◽  
Christopher S. Melhus ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Choroidal Melanoma

Incidence of radiation retinopathy after high-dosage single-fraction gamma knife radiosurgery for choroidal melanoma

Ophthalmology ◽  
2002 ◽  
Vol 109 (5) ◽  
pp. 909-913 ◽  
Author(s):  
Anton Haas ◽  
Oliver Pinter ◽  
Georg Papaefthymiou ◽  
Martin Weger ◽  
Andrea Berghold ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Choroidal Melanoma ◽  
Radiation Retinopathy ◽  
Single Fraction

Influence of single-fraction Gamma-Knife radiosurgery on ocular surface and tear function in choroidal melanoma patients

2013 ◽  
Vol 97 (4) ◽  
pp. 466-470 ◽  
Author(s):  
Jutta Horwath-Winter ◽  
Mona Regina Schneider ◽  
Werner Wackernagel ◽  
Dieter Rabensteiner ◽  
Ingrid Boldin ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Ocular Surface ◽  
Gamma Knife Radiosurgery ◽  
Choroidal Melanoma ◽  
Single Fraction ◽  
Melanoma Patients

Analysis of Visual Toxicity After Gamma Knife Radiosurgery for Treatment of Choroidal Melanoma

2010 ◽  
pp. 1
Author(s):  
Michael D. Chan ◽  
Christopher S. Melhus ◽  
John E. Mignano ◽  
Daniel Do-Dai ◽  
Jay S. Duker ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Choroidal Melanoma

Preliminary experience in the treatment of choroidal melanoma with gamma knife radiosurgery

2000 ◽  
Vol 93 (supplement_3) ◽  
pp. 177-179 ◽  
Author(s):  
Robert Woodburn ◽  
Ronald Danis ◽  
Robert Timmerman ◽  
Thomas Witt ◽  
Thomas Ciulla ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Choroidal Melanoma ◽  
Vitreous Hemorrhage ◽  
Infraorbital Nerve ◽  
Tumor Control ◽  
Tumor Diameter ◽  
Content Type ◽  
Fine Print

Object. The authors report their early results from an ongoing experience treating patients with choroidal melanoma by using gamma knife radiosurgery (GKS). Methods. Between September 1998 and March 2000, 11 patients were treated for choroidal melanoma. Treatment was facilitated with specialized frame placement. Eye immobilization was accomplished with supra- and infraorbital nerve block and tethering sutures to the periorbital tissue. Magnetic resonance imaging was performed to localize the tumor for treatment planning. Plugging patterns were used to steer fall-off radiation away from the fovea, optic nerve, or lens. Tumor volume, tumor location relative to critical structures, and dose to critical structures were determined using GammaPlan. Tumor response was determined using ultrasonography. Toxicity was determined by clinical assessment, visual acuity testing, and ophthalmoscopy. All 11 patients successfully completed the treatment. In every case, 40 Gy was prescribed to the 50% isodose, which completely encompassed all visible tumor. Tumor height ranged from 2.9 to 7 mm. The tumor diameter ranged from 6 to 13 mm. The range of follow up was 2 to 19 months. No tumor has progressed. One patient had improvement in vision because of improvement in retinal detachment. Two patients experienced visual decline. One patient's visual decline was due to a vitreous hemorrhage, and the other's was due to hard exudates encroaching on the macula. One patient has developed a dry eye that is managed effectively with topical eye lubricants. Conclusions. This preliminary experience demonstrates that GKS is a feasible treatment option for small- to medium-sized choroidal melanomas. Longer follow up and additional patients will be required to improve the assessment and the ultimate tumor control and toxicity in this ongoing series.

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