scholarly journals Trabeculectomy versus canaloplasty ( TVC study) in the treatment of patients with open‐angle glaucoma: a prospective randomized clinical trial

2015 ◽  
Vol 93 (8) ◽  
pp. 753-761 ◽  
Author(s):  
Juliane Matlach ◽  
Christine Dhillon ◽  
Johannes Hain ◽  
Günther Schlunck ◽  
Franz Grehn ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Prospective Randomized Clinical Trial

scholarly journals Viscocanalostomy versus trabeculectomy for primary open angle glaucoma: 4-year prospective randomized clinical trial

Eye ◽  
2007 ◽  
Vol 23 (9) ◽  
pp. 1802-1807 ◽  
Author(s):  
D F Gilmour ◽  
T D Manners ◽  
H Devonport ◽  
Z Varga ◽  
A L Solebo ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Prospective Randomized Clinical Trial

scholarly journals Phaco-UCP; combined phacoemulsification and ultrasound ciliary plasty versus phacoemulsification alone for management of coexisting cataract and open angle glaucoma: a randomized clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Magda A. Torky ◽  
Yousef A. Alzafiri ◽  
Ameera G. Abdelhameed ◽  
Eman A. Awad
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Open Angle Glaucoma ◽  
Surgical Techniques ◽  
Glaucoma Surgery ◽  
Median Number ◽  
Control Group ◽  
Open Angle ◽  
Link Type ◽  
A New Technique

Abstract Background Various surgical techniques have been described, to be combined with cataract surgery in glaucoma patients, aiming for an additional reduction of intraocular pressure (IOP), hence minimizing the burden of anti-glaucoma medication (AGM). Ultrasound ciliary plasty (UCP) is a recent microinvasive glaucoma surgery (MIGS) recommended for primary and refractory glaucoma. This study was conducted to evaluate the safety and efficacy of a new technique; combined phacoemulsification and ultrasound ciliary plasty (Phaco-UCP) as a primary surgical treatment for coexisting cataract and open angle glaucoma. Methods A randomized clinical trial, including 61 eyes of 61 patients with visually significant cataract and open angle glaucoma, randomized to either Phaco-UCP (study group; 31 eyes) or phacoemulsification alone (Phaco-alone) (control group; 30 eyes). Primary outcomes included reduction in IOP and/or the number of AGM. Secondary outcomes included visual acuity improvement and complications. Qualified Success was defined as an IOP reduction ≥ 20% from baseline value, with an IOP 6–21 mmHg, with no additional AGM or glaucoma surgery. Failure was defined as either < 20% IOP reduction, despite AGM use, the need of glaucoma surgeries or serious complications. Results At 18 months postoperatively, Phaco-UCP group had a median IOP reduction of 7 mmHg (Q1, Q3 = 3, 10) compared to 2 mmHg (Q1, Q3 = 2, 3) in Phaco-alone group (P < 0.001). Phaco-UCP group had significantly higher success rate at all time points reaching 67.7% at the last follow-up versus 16.7% only in Phaco-alone group (P< 0.001). The median number of AGM significantly decreased from [3 (Q1, Q3 = 2, 4), 3 (Q1, Q3 = 2,3)] respectively, (P =0.3)] at baseline to [1 (Q1,Q3 = 1, 2), 2 (Q1,Q3 = 2, 2)] respectively, (P < 0.001)] at 18 months postoperatively. No serious intraoperative or postoperative complications were encountered in either group. Conclusion Phaco-UCP is a simple, safe and effective procedure for management of coexisting cataract and open angle glaucoma. Trial registration ClinicalTrials.gov identifier, NCT04430647; retrospectively registered. June 12, 2020.

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