Highlights in heart and lung failure from the annual EACTS Meeting

2021 ◽  
Author(s):  
Jason J. Han ◽  
Aakash M. Shah ◽  
Max Shin ◽  
Nahush A. Mokadam
Keyword(s):  
Lung Failure

Acute lung failure due to hypereosinophilic syndrome after pneumonectomy

2019 ◽  
Author(s):  
G Yavuz ◽  
T Kauke ◽  
OM Glück ◽  
T Weig ◽  
K Milger-Kneidinger ◽  
...  
Keyword(s):  
Hypereosinophilic Syndrome ◽  
Acute Lung Failure ◽  
Lung Failure

The Evolution of Pulmonary Hypertension in Terminal Lung Failure

2020 ◽  
Author(s):  
S. Barbara ◽  
M. Sebastian ◽  
C. Hagl ◽  
K. Nikolaus ◽  
C. Schneider ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Lung Failure

Transport of newborns with acute lung failure in the pre-ECMO situation and on ECMO

2006 ◽  
Vol 210 (S 5) ◽  
Author(s):  
F Loersch ◽  
R Gerull ◽  
S Hien ◽  
S Demirakca ◽  
I Jester ◽  
...  
Keyword(s):  
Acute Lung Failure ◽  
Lung Failure

scholarly journals Clinical Differences between COVID-19 and a COVID-Like Syndrome

2021 ◽  
Vol 10 (11) ◽  
pp. 2519
Author(s):  
Pierpaolo Di Micco ◽  
Giuseppe Camporese ◽  
Vincenzo Russo ◽  
Giuseppe Cardillo ◽  
Egidio Imbalzano ◽  
...  
Keyword(s):  
False Negative ◽  
Nasopharyngeal Swab ◽  
Similar Group ◽  
Risk Of Infection ◽  
Hospital Workers ◽  
Serological Tests ◽  
Clinical Presentations ◽  
The World ◽  
Lung Failure ◽  
The Difference

COVID-19 is an infection due to SARS-CoV-2; this virus has been identified as the cause of the present pandemic. Several typical characteristics are present in this infection, in particular pneumonia with possible lung failure, but atypical clinical presentations are being described daily by physicians around the world. Ground-glass opacities with pneumonia are the most common and dangerous presentations of the COVID-19 disease, and they are usually associated with positive nasopharyngeal swab (NPS) tests with detectable SARS-CoV-2 viral RNA. Compared to the general population, hospital workers have been at a greater risk of infection ever since the first patients were hospitalized. However, hospital workers have also been reported as having COVID-like symptoms despite repeated negative swab tests but having tested positive for SARS-CoV-2 antibodies with serological tests. We can postulate that a COVID-like syndrome is possible, in particular in hospital workers, that is characterized by symptoms similar to those of COVID-19, but with repeated negative nasopharyngeal swabs. These repeated negative NSPs make the difference in daily clinical management with people that experienced a single false negative nasopharyngeal swab; furthermore, a clear clinical differentiation of these situations is still lacking in the literature. For this reason, here, we report our main findings from a cohort of patients with a COVID-like syndrome compared to a similar group affected by typical COVID-19.

scholarly journals SARS-CoV-2 Virus Manifestations in the Gastrointestinal Tract: Therapeutic Implications

2020 ◽  
pp. 1-7
Author(s):  
André Jefremow ◽  
Markus F. Neurath
Keyword(s):  
Gastrointestinal Tract ◽  
Gi Tract ◽  
Therapeutic Implications ◽  
The World ◽  
Lung Failure ◽  
Novel Virus

<b><i>Background:</i></b> About 1 year ago a novel virus – SARS-CoV-2 – began to spread around the world. It can lead to the disease COVID-19, which has caused more than 1 million deaths already. <b><i>Summary:</i></b> While it was first recognized as a disease leading to pneumonia and lung failure, we know by now that COVID-19 is more complex. COVID-19 is a systemic hyperinflammatory disease affecting not only the lungs, but also many other organs. Especially the gastrointestinal (GI) tract is often involved in COVID-19. <b><i>Key Messages:</i></b> This review provides an overview of the different affected organs of the GI tract and offers information on how gastroenterologists should take care of their patients with different GI disorders.

scholarly journals Acute Lung Failure

2011 ◽  
Vol 32 (05) ◽  
pp. 607-625 ◽  
Author(s):  
Rob Sweeney ◽  
Daniel McAuley ◽  
Michael Matthay
Keyword(s):  
Acute Lung Failure ◽  
Lung Failure

scholarly journals Perfusion of nonventilated lung: failure of hypoxic vasoconstriction?

1983 ◽  
Vol 141 (1) ◽  
pp. 151-156 ◽  
Author(s):  
HD Sostman ◽  
RD Neumann ◽  
A Gottschalk ◽  
RH Greenspan
Keyword(s):  
Hypoxic Vasoconstriction ◽  
Lung Failure

A randomized clinical trial of home telemonitoring in patients with advanced heart and lung diseases.

2021 ◽  
pp. 1357633X2110597
Author(s):  
Carlos Hernandez-Quiles ◽  
Máximo Bernabeu-Wittel ◽  
Bosco Barón-Franco ◽  
Alfonso Aguirre Palacios ◽  
M Rocio Garcia-Serrano ◽  
...  
Keyword(s):  
Health Care ◽  
Clinical Trial ◽  
Functional Status ◽  
Integrated Care ◽  
Lung Diseases ◽  
Care Model ◽  
Emergency Admissions ◽  
Perceived Satisfaction ◽  
Lung Failure ◽  
Functional Features

Brief Summary The addition of home monitoring to an integrated care model in patients with advanced chronic heart/lung diseases decreases mortality, hospital and emergency admissions, improves functional status, HRQoL, and is cost-effective. Background Telemonitoring is a promising implement for medicine, but its efficacy is unknown in patients with advanced heart and lung failure (AHLF). Objective To determine the efficacy of a telemonitoring system added to coordinated clinical care in patients with AHLF. Design Randomized phase 3 multicenter clinical trial with parallel groups in adult patients. Participants Five spanish centers including patients with AHLF at discharge or in out-patient clinics. Intervention Patients were randomly assigned to receive a remote bio-parameters telemonitoring system (TELECARE) or best usual care (UCARE). TELECARE patients were provided with devices that collected symptoms and bio-parameters, and transferred them synchronously to a call-center, with a real-time health-care response. Main Measures Primary end point was the need of admissions/emergency room visits at 45, 90, 180 days. Secondary end points included health care requirements, mortality, functional assessment, health related quality of life (HRQoL), perceived satisfaction, and cost-efficacy. Results 510 patients were included (54.5% women, median age 76.5 years; 63.1% suffered heart failure, 13.9% lung failure, and 22.9% both conditions). Clinical and functional features were comparable in both arms. TELECARE globally needed less admissions with respect UCARE after 45 days of inclusion (35.4% vs. 46.9%, p < 0.05). This tendency was maintained in the subgroups of patients with multimorbidity (34.2% vs. 46.9%, p < 0.05), intermediate risk of mortality (36.5% vs. 51.1%, p < 0.05), and those included after hospital discharge (34.9% vs. 50.5%, p < 0.01). HRQoL significantly improved (TELECARE/UCARE EuroQol baseline of 56.2 ± 18.2/55.1 ± 19.7, p = 0.054, and 64 ± 19.9/56.3 ± 21.6; p < 0.01 at the end), and perceived satisfaction was also higher (6.77 ± 0.52 vs. 6.62 ± 0.81, p < 0.001; highest possible score = 7). A trend to mortality decrease was also observed (12.9% vs. 19.3%, p = 0.13). TELECARE was cost-efficacious (TELECARE/UCARE QALY 3.94 Euros/0.81Euros). Conclusions The addition of a telemonitoring system to an integrated care model in patients with AHLF decreases hospital and emergency admissions, improves functional status as well as HRQoL, and is cost-efficacious.

The physiology of extracorporeal membrane oxygenation: The Fick principle

Perfusion ◽  
2021 ◽  
pp. 026765912110559
Author(s):  
Hoong Lim
Keyword(s):  
Blood Flow ◽  
Extracorporeal Membrane Oxygenation ◽  
Arterial Oxygen Saturation ◽  
Arterial Oxygen ◽  
Fick Principle ◽  
Membrane Oxygenation ◽  
Lung Failure ◽  
Va Ecmo ◽  
The Relationship ◽  
Vv Ecmo

Extracorporeal membrane oxygenation (ECMO) can be delivered in veno-arterial (VA) and veno-venous (VV) configurations based on the cannulation strategy. VA and VV ECMO are delivered primarily for haemodynamic and respiratory support in patients with severe heart and lung failure, respectively. The Fick principle describes the relationship between blood flow and oxygen consumption – key parameters in the physiological management of extracorporeal support. This review will discuss the application of the Fick principle in: (i) recirculation in VV ECMO; (ii) the quantification of oxygen delivery (DO2) in VV ECMO and (iii) the quantification of transpulmonary blood flow and systemic arterial oxygen saturation in VA ECMO.

scholarly journals Angiotensin-converting enzyme 2 protects from severe acute lung failure

Nature ◽  
2005 ◽  
Vol 436 (7047) ◽  
pp. 112-116 ◽  
Author(s):  
Yumiko Imai ◽  
Keiji Kuba ◽  
Shuan Rao ◽  
Yi Huan ◽  
Feng Guo ◽  
...  
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Converting Enzyme ◽  
Angiotensin Converting Enzyme 2 ◽  
Acute Lung Failure ◽  
Lung Failure
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