In vitro evaluation of multi‐objective physiological control of the centrifugal blood pump

2020 ◽  
Vol 44 (8) ◽  
pp. 785-796 ◽  
Author(s):  
Tarcisio Leao ◽  
Bruno Utiyama ◽  
Jeison Fonseca ◽  
Eduardo Bock ◽  
Aron Andrade
2009 ◽  
Vol 33 (10) ◽  
pp. 798-804 ◽  
Author(s):  
Ryo Kosaka ◽  
Osamu Maruyama ◽  
Masahiro Nishida ◽  
Toru Yada ◽  
Sakae Saito ◽  
...  

ASAIO Journal ◽  
2001 ◽  
Vol 47 (6) ◽  
pp. 692-695 ◽  
Author(s):  
Atsuhiro Mitsumaru ◽  
Ryohei Yozu ◽  
Toru Matayoshi ◽  
Masanori Morita ◽  
Hankei Shin ◽  
...  

ASAIO Journal ◽  
2006 ◽  
Vol 52 (2) ◽  
pp. 23A
Author(s):  
Hideo Hoshi ◽  
Junichi Asama ◽  
Chikara Hara ◽  
Wataru Hijikata ◽  
Tadahiko Shinshi ◽  
...  

2021 ◽  
pp. 039139882110525
Author(s):  
Akiko Oota-Ishigaki ◽  
Takashi Yamane ◽  
Daisuke Sakota ◽  
Ryo Kosaka ◽  
Osamu Maruyama ◽  
...  

Low-flow blood pumps rated under 1 L/min are emerging for new medical applications, such as hemofiltration in acute use. In those pumps, platelet adhesion and aggregation have to be carefully considered because of clogging risk in the filter part. To find an acceptable hemocompatibility that can be applied to low-flow centrifugal blood pump design, the platelet aggregation index, clogging on a micromesh filter, and the hemolysis index were investigated using a low-flow blood pump designed for hemofiltration use. We conducted circulation testing in vitro using fresh porcine blood and two centrifugal pumps with different impeller inlet shapes. The Negative Log Platelet Aggregation Threshold Index (NL-PATI), which reflects the ability of residual platelets to aggregate, and flow rate were measured during reflux for 60 min, and the Normalized Index of Hemolysis (NIH (g/20 min)) was calculated. In addition, blood cell clogging after reflux was observed on the micromesh filter by SEM, and the adhesion rate was calculated. Our results showed that the platelet clogging on the micromesh filter occurred when the average NL-PATI was greater than 0.28 and the average NIH (g/20 min) was greater than 0.01. In contrast, platelet clogging on the micromesh was suppressed when NL-PATI was less than 0.17 and the NIH (g/20 min) was less than 0.003. These values might be used as acceptable hemocompatibility of low-flow centrifugal blood pumps with suppressed platelet clogging for hemofiltration pumps.


1992 ◽  
Vol 14 (4) ◽  
pp. 275-286 ◽  
Author(s):  
B. Knierbein ◽  
N. Rosarius ◽  
A. Unger ◽  
H. Reul ◽  
G. Rau

2009 ◽  
Vol 33 (9) ◽  
pp. 704-713 ◽  
Author(s):  
Takeshi Someya ◽  
Mariko Kobayashi ◽  
Satoshi Waguri ◽  
Tomohiro Ushiyama ◽  
Eiki Nagaoka ◽  
...  

Author(s):  
Yosuke TOMARI ◽  
Osamu MARUYAMA ◽  
Daisuke SUGIYAMA ◽  
Masahiro NISHIDA ◽  
Tatsuo TSUTSUI ◽  
...  

ASAIO Journal ◽  
2003 ◽  
Vol 49 (2) ◽  
pp. 150
Author(s):  
T Kitano ◽  
T Tokuno ◽  
K Yamazaki ◽  
S Kihara ◽  
M Umezu ◽  
...  

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