Development of an Optical Detector of Thrombus Formation on the Pivot Bearing of a Rotary Blood Pump

2016 ◽  
Vol 40 (9) ◽  
pp. 834-841 ◽  
Author(s):  
Daisuke Sakota ◽  
Tatsuki Fujiwara ◽  
Katsuhiro Ouchi ◽  
Katsuyuki Kuwana ◽  
Hiroyuki Yamazaki ◽  
...  
Keyword(s):  
Thrombus Formation ◽  
Blood Pump ◽  
Rotary Blood Pump ◽  
Optical Detector ◽  
Pivot Bearing

CFD Based Prediction Method of Thrombus Formation in Shear Flow and Its Validation

2008 ◽  
Author(s):  
Masaaki Tamagawa ◽  
Sho Nagahama
Keyword(s):  
Lattice Boltzmann ◽  
Shear Flows ◽  
Thrombus Formation ◽  
Prediction Method ◽  
Blood Pump ◽  
Rotary Blood Pump ◽  
Step Flow ◽  
Orifice Flow ◽  
Computational Fluid Dynamics Cfd ◽  
Boltzmann Method

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, the thrombus formation in blood plasma flow is visualized, and modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow.

A Pivot Bearing-Supported Centrifugal Pump for a Long-Term Assist Heart

1997 ◽  
Vol 20 (4) ◽  
pp. 222-228 ◽  
Author(s):  
T. Nakazawa ◽  
Y. Ohara ◽  
R. Benkowski ◽  
K. Makinouchi ◽  
Y. Takami ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Centrifugal Pump ◽  
Thrombus Formation ◽  
Left Ventricular ◽  
Production Model ◽  
Blood Pump ◽  
Preliminary Evaluation ◽  
Centrifugal Blood Pump ◽  
Normal Ranges ◽  
Pivot Bearing

A pivot bearing-supported centrifugal blood pump has been developed. It is a compact, cost effective, and anti-thrombogenic pump with anatomical compatibility. A preliminary evaluation of five paracorporeal left ventricular assist studies were performed on pre-conditioned bovine (70-100 kg), without cardiopulmonary bypass and aortic cross-clamping. The inflow cannula was inserted into the left ventricle (LV) through the apex and the outflow cannula affixed with a Dacron vascular graft was anastomosed to the descending aorta. All pumps demonstrated trouble free performance over a two-week screening period. Among these five studies, three implantations were subjected for one month system validation studies. All the devices were trouble free for longer than 1 month. (35, 34, and 31 days). After achieving one month studies, all experiments were terminated. There was no evidence of device induced thrombus formation inside the pump. The plasma free hemoglobin levels were within normal ranges throughout all experiments. As a consequence of these studies, a mass production model C1E3 of this pump was fabricated as a short-term assist pump. This pump has a Normalized Index of Hemolysis of 0.0007 mg/100L and the estimated wear life of the impeller bearings is longer than 8 years. The C1E3 will meet the clinical requirements as a cardiopulmonary bypass pump. For the next step, a miniaturized pivot bearing centrifugal blood pump PI-601 has been developed for use as a permanently implantable device after design optimization. The evolution from C1E3 to the PI-601 converts this pivot bearing centrifugal pump as a totally implantable centrifugal pump. A pivot bearing centrifugal pump will become an ideal assist pump for the patients with failing heart.

Feasibility of the Optical Imaging of Thrombus Formation in a Rotary Blood Pump by Near-Infrared Light

2014 ◽  
Vol 38 (9) ◽  
pp. 733-740 ◽  
Author(s):  
Daisuke Sakota ◽  
Tomotaka Murashige ◽  
Ryo Kosaka ◽  
Masahiro Nishida ◽  
Osamu Maruyama
Keyword(s):  
Optical Imaging ◽  
Near Infrared ◽  
Thrombus Formation ◽  
Infrared Light ◽  
Blood Pump ◽  
Rotary Blood Pump ◽  
Near Infrared Light

Effects of the Design of a Rotary Blood Pump on Hemocompatibility

2021 ◽  
Author(s):  
M. V. Denisov ◽  
M. Walter ◽  
S. Leonhard ◽  
D. V. Telyshev
Keyword(s):  
Blood Pump ◽  
Rotary Blood Pump

Development of Rotary Blood Pump Technology: Past, Present, and Future

2000 ◽  
Vol 24 (6) ◽  
pp. 412-420 ◽  
Author(s):  
Yukihiko Nosé ◽  
M. Yoshikawa ◽  
S. Murabayashi ◽  
T. Takano
Keyword(s):  
Blood Pump ◽  
Rotary Blood Pump

scholarly journals 3D Printing of Functional Assemblies with Integrated Polymer-Bonded Magnets Demonstrated with a Prototype of a Rotary Blood Pump

2018 ◽  
Vol 8 (8) ◽  
pp. 1275 ◽  
Author(s):  
Kai von Petersdorff-Campen ◽  
Yannick Hauswirth ◽  
Julia Carpenter ◽  
Andreas Hagmann ◽  
Stefan Boës ◽  
...  
Keyword(s):  
Fused Deposition Modeling ◽  
Permanent Magnets ◽  
Low Cost ◽  
Magnetic Bearing ◽  
Blood Pump ◽  
Rotary Blood Pump ◽  
Pump Impeller ◽  
Fused Deposition ◽  
Magnetic Components ◽  
Deposition Modeling

Conventional magnet manufacturing is a significant bottleneck in the development processes of products that use magnets, because every design adaption requires production steps with long lead times. Additive manufacturing of magnetic components delivers the opportunity to shift to agile and test-driven development in early prototyping stages, as well as new possibilities for complex designs. In an effort to simplify integration of magnetic components, the current work presents a method to directly print polymer-bonded hard magnets of arbitrary shape into thermoplastic parts by fused deposition modeling. This method was applied to an early prototype design of a rotary blood pump with magnetic bearing and magnetic drive coupling. Thermoplastics were compounded with 56 vol.% isotropic NdFeB powder to manufacture printable filament. With a powder loading of 56 vol.%, remanences of 350 mT and adequate mechanical flexibility for robust processability were achieved. This compound allowed us to print a prototype of a turbodynamic pump with integrated magnets in the impeller and housing in one piece on a low-cost, end-user 3D printer. Then, the magnetic components in the printed pump were fully magnetized in a pulsed Bitter coil. The pump impeller is driven by magnetic coupling to non-printed permanent magnets rotated by a brushless DC motor, resulting in a flow rate of 3 L/min at 1000 rpm. For the first time, an application of combined multi-material and magnet printing by fused deposition modeling was shown. The presented process significantly simplifies the prototyping of products that use magnets, such as rotary blood pumps, and opens the door for more complex and innovative designs. It will also help postpone the shift to conventional manufacturing methods to later phases of the development process.

Effect of Tubing Length Pump on Flow Derived Index During Rotary Blood Pump Support

2017 ◽  
Author(s):  
Thananya Khienwad ◽  
Ronnachit Deepankaew ◽  
Praemai Wannawat ◽  
Phornphop Naiyanetr
Keyword(s):  
Blood Pump ◽  
Rotary Blood Pump

CFD Study of Thrombus Formation on Shear Blood Flows by Using Modified Lattice Boltzmann Method and Thrombus Observation

2008 ◽  
Author(s):  
Masaaki Tamagawa
Keyword(s):  
Lattice Boltzmann Method ◽  
Lattice Boltzmann ◽  
Shear Flows ◽  
Thrombus Formation ◽  
Prediction Method ◽  
Rotary Blood Pump ◽  
Blood Flows ◽  
Orifice Flow ◽  
Computational Fluid Dynamics Cfd ◽  
Boltzmann Method

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, the thrombus formation in blood plasma flow is visualized, and modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow.

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