scholarly journals Placental location and pregnancy outcomes in nulliparous women: A population‐based cohort study

2019 ◽  
Vol 98 (8) ◽  
pp. 988-996 ◽  
Author(s):  
Michaela Granfors ◽  
Olof Stephansson ◽  
Margit Endler ◽  
Maria Jonsson ◽  
Anna Sandström ◽  
...  
2018 ◽  
Vol 154 (6) ◽  
pp. S-624
Author(s):  
Han Hee Lee ◽  
Bo-In Lee ◽  
Kang-Moon Lee ◽  
Jin Su Kim ◽  
Jae Myung Park ◽  
...  

2018 ◽  
Vol 154 (1) ◽  
pp. S105
Author(s):  
Han Hee Lee ◽  
Jung Min Bae ◽  
Bo-In Lee ◽  
Kang-Moon Lee ◽  
Jeong Ha Wie ◽  
...  

2020 ◽  
Author(s):  
Se Jin Lee ◽  
Hyun Sun Ko ◽  
Sunghun Na ◽  
Jin Young Bae ◽  
Won Joon Seong ◽  
...  

Abstract Background: Our objective was to evaluate risks of adverse obstetric outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy. Methods: We analyzed the national health insurance database, which covers almost the entire Korean population, between 2004 and 2015. The risks of adverse pregnancy outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy, compared to those in women without a diagnosed myoma, were analyzed in multivariate logistic regression analysis. Results: During the study period, 38,402 women with diagnosed myoma(s), 9,890 women with a history of myomectomy, and 740,675 women without a diagnosed myoma gave birth. Women with a history of diagnosed myoma(s) and women with a history of myomectomy had significantly higher risks of cesarean section (aOR 1.13, 95% CI 1.1-1.16 and aOR 7.46, 95% CI 6.97-7.98, respectively) and placenta previa (aOR 1.41, 95% CI 1.29-1.54 and aOR 1.58, 95% CI 1.35-1.83, respectively), compared to women without a diagnosed myoma. And the risk of uterine rupture was significantly higher in women with previous myomectomy (aOR 12.78, 95% CI 6.5-25.13), compared to women without a diagnosed myoma, which was much increased (aOR 41.35, 95% CI 16.18-105.69) in nulliparous women. The incidence of uterine rupture was the highest at delivery within one year after myomectomy and decreased over time after myomectomy. Conclusions: Women with a history of myomectomy had significantly higher risks of cesarean section and placenta previa compared to women without a diagnosed myoma.


2019 ◽  
Vol 37 (13) ◽  
pp. 1364-1376
Author(s):  
Anura W.G. Ratnasiri ◽  
Lauren Gordon ◽  
Ronald A. Dieckmann ◽  
Henry C. Lee ◽  
Steven S. Parry ◽  
...  

Abstract Objective This study aimed to determine associations between maternal cigarette smoking and adverse birth and maternal outcomes. Study Design This is a 10-year population-based retrospective cohort study including 4,971,896 resident births in California. Pregnancy outcomes of maternal smokers were compared with those of nonsmokers. The outcomes of women who stopped smoking before or during various stages of pregnancy were also investigated. Results Infants of women who smoked during pregnancy were twice as likely to have low birth weight (LBW) and be small for gestational age (SGA), 57% more likely to have very LBW (VLBW) or be a preterm birth (PTB), and 59% more likely to have a very PTB compared with infants of nonsmokers. During the study period, a significant widening of gaps developed in both rates of LBW and PTB and the percentage of SGA between infants of maternal smokers and nonsmokers. Conclusion Smoking during pregnancy is associated with a significantly increased risk of adverse birth and maternal outcomes, and differences in rates of LBW, PTB, and SGA between infants of maternal smokers and nonsmokers increased during this period. Stopping smoking before pregnancy or even during the first trimester significantly decreased the infant risks of LBW, PTB, SGA, and the maternal risk for cesarean delivery.


2009 ◽  
Vol 36 (9) ◽  
pp. 1903-1909 ◽  
Author(s):  
CONSTANCE J. ULFF-MØLLER ◽  
KRISTIAN T. JØRGENSEN ◽  
BO V. PEDERSEN ◽  
NETE M. NIELSEN ◽  
MORTEN FRISCH

Objective.The female predominance in systemic lupus erythematosus (SLE) suggests the possible involvement of reproductive factors in its etiology. We evaluated the relationship between parity and pregnancy losses and subsequent risk of SLE in a population-based cohort study.Methods.We followed 4.4 million Danes aged 15–69 years for first inpatient hospitalizations for SLE between 1977 and 2004. As measures of relative risk, we used Poisson regression-derived hospitalization rate ratios (RR) with 95% confidence intervals (CI) for cohort members with different reproductive histories.Results.Overall, 1614 women and 274 men were hospitalized with SLE during 88.9 million person-years of followup. Number of children was unrelated to SLE risk in men, but women with at least one liveborn child were at lower risk than nulliparous women (RR 0.74; 95% CI 0.64–0.86), and women with 2 or more children were at lower risk than 1-child mothers. Recurrent idiopathic pregnancy losses, including spontaneous abortions, missed abortions, and stillbirths, were associated with markedly increased SLE risk (RR 3.50; 95% CI 2.38–4.96, for 2+ vs none; p < 0.001).Conclusion.Nulliparous women, 1-child mothers, and women who experience spontaneous abortions, missed abortions, or stillbirths are at increased SLE risk. Theoretically, immunological processes involved in subfertility or idiopathic pregnancy losses might act as initiating or contributing factors in some cases of SLE. However, considering the well established excess of pregnancy complications in women with established SLE, the observed associations more likely reflect the effect of subclinical immunological processes in women destined to develop SLE.


2017 ◽  
Vol 86 (6) ◽  
pp. 816-824 ◽  
Author(s):  
Shi Chen ◽  
Xiang Zhou ◽  
Huijuan Zhu ◽  
Hongbo Yang ◽  
Fengying Gong ◽  
...  

2017 ◽  
Vol 96 (7) ◽  
pp. 812-820 ◽  
Author(s):  
Miia Artama ◽  
Jemina Braumann ◽  
Jani Raitanen ◽  
Jukka Uotila ◽  
Mika Gissler ◽  
...  

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