Amniotic fluid erythropoietin and neonatal outcome in pregnancies complicated by intrauterine growth restriction before 34 gestational weeks

2015 ◽  
Vol 94 (3) ◽  
pp. 288-294 ◽  
Author(s):  
Laura Seikku ◽  
Leena Rahkonen ◽  
Minna Tikkanen ◽  
Esa Hämäläinen ◽  
Petri Rahkonen ◽  
...  
2007 ◽  
Vol 31 (1) ◽  
pp. 48-54 ◽  
Author(s):  
K. Mäkikallio ◽  
J. Räsänen ◽  
T. Mäkikallio ◽  
O. Vuolteenaho ◽  
J. C. Huhta

1999 ◽  
Vol 180 (3) ◽  
pp. 703-710 ◽  
Author(s):  
Salha S. Daniel ◽  
Raymond I. Stark ◽  
Pamela J. Tropper ◽  
L.Stanley James

2016 ◽  
pp. 99-102
Author(s):  
G.S. Yanyuta ◽  
◽  
T.R. Savka ◽  
A.V. Basystiy ◽  
◽  
...  

The objective: to determine the importance of a comprehensive ultrasound check of a foetus with arrested development. Patients and methods. Some 185 pregnant women with foetuses with arrested development were examined, including their amniotic fluid volume and Doppler velocimetry of foetal circulation. Results. Reliable changes in the placenta, amniotic fluid volume and Doppler parameters of fetal circulation. Conclusions. The stages and scale of the pathological process in a foetus with arrested development can be clearly determined with the help of a comprehensive ultrasound check. Key words: intrauterine growth restriction, pregnancy, blood flow in the uterus and placenta of pregnant women and in foetuses, Doppler.


2005 ◽  
Vol 184 (1) ◽  
pp. 179-189 ◽  
Author(s):  
A M Carter ◽  
M J Kingston ◽  
K K Han ◽  
D M Mazzuca ◽  
K Nygard ◽  
...  

The IGF system is one of the most important endocrine and paracrine growth factor systems that regulate fetal and placental growth. We hypothesized that intrauterine growth restriction (IUGR) in guinea pigs is mediated by the altered expression of IGFs and/or IGF binding protein (BP) mRNAs in tissues and is related to growth of specific tissues. IUGR was induced by unilateral uterine artery ligation on day 30 of gestation, and fetal plasma, amniotic fluid and tissue samples were collected at 55–57 days (term about 68 days) from paired IUGR and control fetuses (n=6). Western ligand blotting and immunoblotting were used to compare IGFBP levels in plasma and amniotic fluid. Total RNA was extracted from placenta and fetal tissues, and the relative abundance of IGF-II and IGFBP-1–6 mRNA was determined by Northern blotting, using species-specific probes where available. IUGR fetuses had decreased (P<0.01, by Student’s t-test) placental weight and body weight with an increase in the brain:liver weight ratio. The principal IGFBPs in fetal plasma migrated at 40–35, 30 and 25 kDa and were identified as IGFBP-3, -2 and -4 respectively. IUGR was associated with elevated plasma IGFBP-2 and IGFBP-4 and reduced IGFBP-3 levels. IGFBPs were detected at low levels in amniotic fluid of control fetuses but at higher levels in IUGR fetuses. In IUGR placentae, there was a small increase in IGFBP-4 mRNA (P<0.05). IGFBP-2 mRNA increased (P<0.001) in liver of IUGR fetuses. IGF-II and IGFBP mRNA expression did not change in fetal muscle. The results are consistent with reduced IGF action, directly or through inhibition by IGFBPs, particularly by circulating and tissue IGFBP-2, as a potential causal factor in decreased growth of the placenta and certain fetal tissues.


2008 ◽  
Vol 28 (10) ◽  
pp. 887-891 ◽  
Author(s):  
Ozgur Dundar ◽  
Pınar Yoruk ◽  
Levent Tutuncu ◽  
Murat Muhcu ◽  
Osman Ipcioglu ◽  
...  

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