Management of bile leak following blunt liver injury: a proposed guideline

2021 ◽  
Author(s):  
June Oo ◽  
Marty Smith ◽  
Ee Jun Ban ◽  
Warren Clements ◽  
Peter Tagkalidis ◽  
...  
Keyword(s):  
Liver Injury ◽  
Bile Leak ◽  
Blunt Liver Injury

Diagnosis and nonsurgical management of bile leak complicated by biloma after blunt liver injury: report of two cases

1998 ◽  
Vol 8 (9) ◽  
pp. 1619-1622 ◽  
Author(s):  
A. De Backer ◽  
H. Fierens ◽  
A. De Schepper ◽  
P. Pelckmans ◽  
P. G. Jorens ◽  
...  
Keyword(s):  
Liver Injury ◽  
Bile Leak ◽  
Blunt Liver Injury ◽  
Nonsurgical Management

Delayed celiotomy for the treatment of bile leak, compartment syndrome, and other hazards of nonoperative management of blunt liver injury

2003 ◽  
Vol 185 (5) ◽  
pp. 492-497 ◽  
Author(s):  
Robert Goldman ◽  
Monica Zilkoski ◽  
Richard Mullins ◽  
John Mayberry ◽  
Clifford Deveney ◽  
...  
Keyword(s):  
Liver Injury ◽  
Compartment Syndrome ◽  
Nonoperative Management ◽  
Bile Leak ◽  
Blunt Liver Injury

Blunt liver injury: 3 hour and 35 minute occlusion of the hepatoduodenal ligament

Injury ◽  
1995 ◽  
Vol 26 (8) ◽  
pp. 547-549
Author(s):  
S. Repše ◽  
E. Gadžijev ◽  
M. Omejc
Keyword(s):  
Liver Injury ◽  
Hepatoduodenal Ligament ◽  
Blunt Liver Injury

scholarly journals Recombinant Factor VIIa Reduces Bleeding after Blunt Liver Injury in a Pig Model of Dilutional Coagulopathy under Severe Hypothermia

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0113979 ◽  
Author(s):  
Henri M. H. Spronk ◽  
Till Braunschweig ◽  
Rolf Rossaint ◽  
Dirk C. Wüst ◽  
Rene van Oerle ◽  
...  
Keyword(s):  
Liver Injury ◽  
Recombinant Factor Viia ◽  
Factor Viia ◽  
Pig Model ◽  
Blunt Liver Injury ◽  
Severe Hypothermia ◽  
Dilutional Coagulopathy

Increasing concentrations of prothrombin complex concentrate induce disseminated intravascular coagulation in a pig model of coagulopathy with blunt liver injury

Blood ◽  
2011 ◽  
Vol 118 (7) ◽  
pp. 1943-1951 ◽  
Author(s):  
Oliver Grottke ◽  
Till Braunschweig ◽  
Henri M. H. Spronk ◽  
Stephanie Esch ◽  
Annette D. Rieg ◽  
...  
Keyword(s):  
Liver Injury ◽  
Blood Loss ◽  
Disseminated Intravascular Coagulation ◽  
Prothrombin Complex Concentrate ◽  
Safety Data ◽  
Control Group ◽  
Total Blood ◽  
Intravascular Coagulation ◽  
Blunt Liver Injury ◽  
Ringer’S Lactate

Abstract Despite increasing use of prothrombin complex concentrate (PCC) to treat hemorrhage-associated coagulopathy, few studies have investigated PCC in trauma, and there is a particular lack of safety data. This study was performed to evaluate PCC therapy in a porcine model of coagulopathy with blunt liver injury. Coagulopathy was induced in 27 anesthetized pigs by replacing approximately 70% blood volume with hydroxyethyl starch 130/0.4 and Ringer's lactate solution; erythrocytes were collected and retransfused. Ten minutes after trauma, animals randomly received PCC (35 or 50 IU/kg) or saline. Coagulation parameters including thromboelastometry, thrombin generation, and blood loss were monitored for 2 hours. Internal organs were examined macroscopically and histologically to determine the presence of emboli and assess liver injury. Total blood loss was significantly lower and survival was higher in both PCC groups versus the control group (P < .05). These outcomes appeared to be dose-independent. Thromboembolism was found in all animals treated with 50 IU/kg PCC; 44% also showed signs of disseminated intravascular coagulation. Liver injury was similar in all animals. In conclusion, 35 IU/kg PCC safely improved coagulation and attenuated blood loss. However, the higher dose of PCC (50 IU/kg) appeared to increase the risk of thromboembolism and disseminated intravascular coagulation.

scholarly journals May liver transaminases substitute for computed tomography in evaluation of blunt liver injury? With special emphasis on serum cut-off levels

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S616
Author(s):  
T. Canbak ◽  
A. Acar ◽  
F. Basak ◽  
A. Ozpek ◽  
A. Kilic ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Liver Injury ◽  
Blunt Liver Injury ◽  
Liver Transaminases
Sign in / Sign up

Export Citation Format

Share Document