Distal intestinal obstruction syndrome: an important differential diagnosis for abdominal pain in patients with cystic fibrosis

2019 ◽  
Vol 90 (5) ◽  
pp. 681-686 ◽  
Author(s):  
Amy Hort ◽  
Ahmer Hameed ◽  
Peter G. Middleton ◽  
Henry C. Pleass
Keyword(s):  
Cystic Fibrosis ◽  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Intestinal Obstruction ◽  
Important Differential Diagnosis ◽  
Distal Intestinal Obstruction Syndrome ◽  
Distal Intestinal Obstruction

Lavage Treatment of Distal Intestinal Obstruction Syndrome in Children With Cystic Fibrosis

PEDIATRICS ◽  
1989 ◽  
Vol 83 (5) ◽  
pp. 727-733
Author(s):  
Sibylle Koletzko ◽  
David A. Stringer ◽  
Geoffrey J. Cleghorn ◽  
Peter R. Durie
Keyword(s):  
Cystic Fibrosis ◽  
Abdominal Pain ◽  
Intestinal Obstruction ◽  
Nasogastric Tube ◽  
Adverse Reactions ◽  
Iliac Fossa ◽  
Medical Attention ◽  
Patient Reported ◽  
Distal Intestinal Obstruction Syndrome ◽  
Distal Intestinal Obstruction

The efficacy, adverse reactions, and long-term effects of intestinal lavage treatment with a balanced electrolyte solution (Golytely) was evaluated in patients with cystic fibrosis and distal intestinal obstruction syndrome. Twenty-two patients with cystic fibrosis (mean age 21.8 years, range 14 to 34 years, 15 boys or men) who sought medical attention because of abdominal pain and a mass in the right iliac fossa received Golytely, 5.6 ± 1.9 L (mean ± 1 SD), either orally (n = 14) or via nasogastric tube (n = 8) during 5.6 ± 2.4 hours. No serious side effects occurred. Serum electrolyte values remained within normal limits. Body weight did not change significantly. Minor adverse reactions included bloating (n = 12), nausea (n = 8), vomiting (n = 1), and chills (n = 3). All but one patient reported impressive relief of symptoms and remained pain free for an average of 3 months (range 1 to 19 months). Symptoms of abdominal pain and radiologic signs of fecal impaction assessed before and after lavage both decreased significantly (P < .0001). During follow-up (mean 15.2 months, range 4 to 26 months), 11 patients required a total of 38 (range one to nine) additional doses of Golytely. Seven patients drank the solution at home (21 treatments); only two patients chose a nasogastric tube. In ten patients with symptoms of recurrent distal intestinal obstruction syndrome prior to institution of therapy, duration of hospitalization was significantly reduced by this treatment (5.1 ± 7.6 v 2.3 ± 6.3 hospital days per annum, P < .02). It is concluded that intestinal lavage is a well-accepted, safe, and effective therapy for distal intestinal obstruction syndrome in patients with cystic fibrosis.

scholarly journals Acute Appendicitis Masquerading Distal Intestinal Obstruction Syndrome in Adult Cystic Fibrosis

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Sushant M. Nanavati ◽  
Hiren Patel ◽  
Gabriel Melki ◽  
Vinod Kumar ◽  
Edward Milman ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Abdominal Pain ◽  
Acute Appendicitis ◽  
Intestinal Obstruction ◽  
Care Program ◽  
Lower Quadrant ◽  
Quadrant Abdominal Pain ◽  
Distal Intestinal Obstruction Syndrome ◽  
Right Lower Quadrant ◽  
Distal Intestinal Obstruction

Overshadowed by Sino-pulmonary infections, Cystic Fibrosis (CF) commonly affects gastrointestinal organs because of secretory and motility dysfunction. Infrequently, these changes result in Distal Intestinal Obstruction Syndrome (DIOS), an increasingly diagnosed gastrointestinal entity in adult Cystic Fibrosis patients. We present a case 22-year-old male who presented to our hospital with right lower quadrant abdominal pain with suspicion of acute appendicitis and was subsequently diagnosed as DIOS. Our case highlights the importance of DIOS as one of the differential diagnosis of right lower quadrant abdominal pain in a patient with a CF, especially for physicians working at community hospitals which may not have a Cystic Fibrosis care program available.

Distal intestinal obstruction syndrome in cystic fibrosis: presentation, outcome and management in a tertiary hospital (2007-2012)

2013 ◽  
Vol 84 (10) ◽  
pp. 740-744 ◽  
Author(s):  
Rami Subhi ◽  
Rachel Ooi ◽  
Felicity Finlayson ◽  
Tom Kotsimbos ◽  
John Wilson ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Intestinal Obstruction ◽  
Tertiary Hospital ◽  
Distal Intestinal Obstruction Syndrome ◽  
Distal Intestinal Obstruction

scholarly journals Distal intestinal obstruction syndrome: a diagnostic and therapeutic challenge in cystic fibrosis

2020 ◽  
Vol 96 (6) ◽  
pp. 732-740 ◽  
Author(s):  
Natascha S. Sandy ◽  
Lilian H.P. Massabki ◽  
Aline C. Gonçalves ◽  
Antonio F. Ribeiro ◽  
Jose D. Ribeiro ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Intestinal Obstruction ◽  
Therapeutic Challenge ◽  
Distal Intestinal Obstruction Syndrome ◽  
Distal Intestinal Obstruction
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