Response to Re: Hepatic resection for malignant liver tumours in the elderly: a systematic review and meta-analysis

2016 ◽  
Vol 86 (3) ◽  
pp. 210-211
Author(s):  
Kevin Phan ◽  
Vincent V. G. An ◽  
Hakeem Ha ◽  
Steven Phan ◽  
Vincent Lam ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hepatic Resection ◽  
Meta Analysis ◽  
The Elderly ◽  
Liver Tumours ◽  
Malignant Liver

scholarly journals Hepatic resection for malignant liver tumours in the elderly: a systematic review and meta-analysis

2015 ◽  
Vol 85 (11) ◽  
pp. 815-822 ◽  
Author(s):  
Kevin Phan ◽  
Vincent Vinh Gia An ◽  
Hakeem Ha ◽  
Steven Phan ◽  
Vincent Lam ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hepatic Resection ◽  
Meta Analysis ◽  
The Elderly ◽  
Liver Tumours ◽  
Malignant Liver

Laparoscopic versus open hepatectomy for malignant liver tumours in the elderly: systematic review and meta-analysis

2021 ◽  
Author(s):  
Ali Yasen Y. Mohamedahmed ◽  
Shafquat Zaman ◽  
Mohamed Albendary ◽  
Jenny Wright ◽  
Hiba Abdalla ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
The Elderly ◽  
Liver Tumours ◽  
Open Hepatectomy ◽  
Malignant Liver

scholarly journals Effectiveness of Oral Nutritional Supplements on Older People with Anorexia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 835
Author(s):  
Mengqi Li ◽  
Si Zhao ◽  
Shuang Wu ◽  
Xiufen Yang ◽  
Hui Feng
Keyword(s):  
Systematic Review ◽  
Body Weight ◽  
Older People ◽  
Energy Intake ◽  
Meta Analysis ◽  
Nutritional Supplements ◽  
The Elderly ◽  
Randomized Controlled ◽  
Oral Nutritional Supplements ◽  
Positive Effect

Background: Nutrition plays an important role in maintaining the overall health of older people. Inadequate intake may lead to impaired body function, higher morbidity, and mortality. Oral nutritional supplements (ONS) showed positive effect on the nutritional status of the elderly; however, systematic evidence is currently lacking on the effect of ONS on the elderly with anorexia. Aims: The current systematic review and meta-analysis included randomized controlled trial (RCT) articles to investigate the effectiveness of ONS on the main aspects of anorexia of aging (AA). Methods: By using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method, researchers independently searched PubMed/MEDLINE, EMBASE, CINAHL, PsycINFO, the Cochrane Library, China National Knowledge Infrastructure (CNKI) and other gray literature resources for publications that met the inclusion criteria by October 2020. The Cochrane Risk of Bias Tools were used for quality assessment. The inverse-variance method was used for the fixed model (FM) while the DerSimonian–Laird method was used for the random model (RM). Respective 95% confidence intervals (95% CIs), mean difference (MD) or standardized mean difference (SMD) was used for indices in terms of effect size (ES). Results: 2497 records were found through the systematic search, while 17 RCTs (n = 1204) were included, with a mean age of 81.9 years (range: 74–87 years). Supplementation occurred in the morning, mid-day, and evening, while the times varied from one to three times a day. The results of meta-analysis showed that, generally, ONS had a positive effect on the overall appetite, MD = 0.18, 95% CI (0.03, 0.33), p = 0.02, and consumption, MD = 1.43, 95% CI (0.01, 2.86), p = 0.05; but not significant in terms of other aspects of appetite: hunger, p = 0.73; fullness, p = 0.60; desire to eat, p = 0.80; preoccupation, p = 0.15. Additionally, it showed an increase in the overall energy intake, SMD = 0.46, 95% CI (0.29, 0.63), p < 0.001, in protein intake, SMD = 0.59, 95% CI (0.16, 1.02), p = 0.007, and in fat intake, MD = 3.47, 95% CI (1.98, 4.97), p < 0.001, while no positive effect was found on carbohydrates intake, p = 0.06. Significance differences were also found in the body weight, SMD = 0.53, 95% CI (0.41, 0.65), p < 0.001, and body mass index (BMI), MD = 0.53, 95% CI (0.12, 0.95), p = 0.01. Moreover, subgroup analyses were conducted according to the nutrient density with no positive results showed except for the low-density ONS on overall energy intake. Conclusions: The results of the present study indicated that ONS had beneficial effects on overall appetite, energy intake, body weight and BMI.

Marital status and mortality in the elderly: A systematic review and meta-analysis

2007 ◽  
Vol 64 (1) ◽  
pp. 77-94 ◽  
Author(s):  
Lamberto Manzoli ◽  
Paolo Villari ◽  
Giovanni M Pirone ◽  
Antonio Boccia
Keyword(s):  
Systematic Review ◽  
Marital Status ◽  
Meta Analysis ◽  
The Elderly

Ileal Pouch Anal Anastomosis in the Elderly: A Systematic Review and Meta‐Analysis

2021 ◽  
Author(s):  
Karina E. Pedersen ◽  
Xue Jia ◽  
Stefan D. Holubar ◽  
Scott R. Steele ◽  
Amy L. Lightner
Keyword(s):  
Systematic Review ◽  
Ileal Pouch ◽  
Meta Analysis ◽  
The Elderly ◽  
Ileal Pouch Anal Anastomosis ◽  
Anal Anastomosis

The effectiveness of serious games in improving memory among elderly people with cognitive impairment: A systematic review and meta-analysis (Preprint)

2021 ◽  
Author(s):  
Alaa Abd-alrazaq ◽  
Dari Alhuwail ◽  
Eiman Al-Jafar ◽  
Arfan Ahmed ◽  
Shuja Mohd Reagu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Working Memory ◽  
Cognitive Impairment ◽  
Verbal Memory ◽  
Serious Games ◽  
Meta Analysis ◽  
The Elderly ◽  
Quality Of Evidence ◽  
Meta Analyses

BACKGROUND Memory, one of the main cognitive functions, is known to decline by age. Serious games have been used for improving memory among the elderly. The effectiveness of serious games in improving memory has been investigated by several systematic reviews; however, they are limited by design and methodological weaknesses. OBJECTIVE This study aims to assess the effectiveness of serious games in improving memory among the elderly with cognitive impairment. METHODS A systematic review of randomized controlled trials (RCTs) was carried out. The search sources included searching 8 databases, screening reference lists of the included studies and relevant reviews, and checking studies that cited the included studies. Two reviewers independently carried out the study selection, data extraction, risk of bias assessment, and quality of evidence appraisal. Extracted data were synthesized using a narrative approach and a statistical approach (i.e., meta-analysis), as appropriate. RESULTS Out of 466 citations retrieved, 18 studies met the eligibility criteria of this review. Of those, 15 RCTs were eventually included in 10 meta-analyses. We found that serious games are more effective than no or passive interventions in improving non-verbal memory (P=0.002) and working memory (P=0.02), but not verbal memory (P=0.13). The review also showed that serious games are more effective than conventional exercises in improving verbal memory (P=0.004), but not for non-verbal memory (P=0.12) and working memory (P=0.49). Serious games were as effective as conventional cognitive activities in improving verbal memory (P=0.07), non-verbal memory (P=0.94), and working memory (P=0.08) among the elderly with cognitive impairment. Lastly, the effect of adaptive serious games on working memory was comparable to non-adaptive serious games (P=0.08). CONCLUSIONS Serious games have the potential to improve verbal, non-verbal, and working memory among elderly people with cognitive impairment. However, our findings should be interpreted cautiously given that most meta-analyses were based on a few studies (≤3) and judged to have a low quality of evidence. Therefore, serious games should be offered as supplemental to existing proven and safe interventions, rather than a complete substitute until further, more robust evidence is available. Future studies should investigate the short and long-term effects of serious games on memory and other cognitive abilities among people from different age groups with or without cognitive impairment.

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