scholarly journals Prevalence of non‐motor symptoms and their association with quality of life in cervical dystonia

2020 ◽  
Vol 142 (6) ◽  
pp. 613-622
Author(s):  
Vladimir Han ◽  
Matej Skorvanek ◽  
Marenka Smit ◽  
Monika Turcanova Koprusakova ◽  
Tialda Hoekstra ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cervical Dystonia ◽  
Motor Symptoms ◽  
Non Motor Symptoms

scholarly journals Emotional well-being and pain could be a greater determinant of quality of life compared to motor severity in cervical dystonia

2020 ◽  
Author(s):  
Lisa Klingelhoefer ◽  
Maximilian Kaiser ◽  
Anna Sauerbier ◽  
Robert Untucht ◽  
Miriam Wienecke ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cervical Dystonia ◽  
Economic Status ◽  
Demographic Data ◽  
Well Being ◽  
Motor Symptoms ◽  
Related Quality ◽  
Health Related ◽  
Non Motor Symptoms

Abstract Non-motor symptoms (NMS) occur in patients with cervical dystonia (CD) but with variable frequencies and impact on health-related quality of life (HRQoL). To define non-motor and motor profiles and their respective impact on HRQoL in CD patients using the newly validated Dystonia Non-Motor Symptoms Questionnaire (DNMSQuest). In an observational prospective multicentre case–control study, we enrolled 61 patients with CD and 61 age- and sex-matched healthy controls (HC) comparing demographic data, motor and non-motor symptoms and HRQoL measurements. 95% CD patients reported at least one NMS. Mean total NMS score was significantly higher in CD patients (5.62 ± 3.33) than in HC (1.74 ± 1.52; p < 0.001). Pain, insomnia and stigma were the most prevalent NMS and HRQoL was significantly impaired in CD patients compared to HC. There was strong correlation of NMS burden with HRQoL (CDQ-24: r = 0.72, EQ-5D: r = − 0.59; p < 0.001) in CD patients. Regression analysis between HRQoL and NMS suggested that emotional well-being (standardized beta = − 0.352) and pain (standardized beta = − 0.291) had a major impact on HRQoL while, in contrast motor severity had no significant impact in this model. Most NMS with the exception of pain, stigma and ADL did not correlate with motor severity. NMS are highly prevalent in CD patients and occur independent of age, sex, disease duration, duration of botulinum neurotoxin therapy and socio-economic status. Specific NMS such as emotional well-being and pain have a major impact on HRQoL and are more relevant than motor severity.

scholarly journals The Parkinson’s Real-World Impact Assessment (PRISM) Study: A European Survey of the Burden of Parkinson’s Disease in Patients and their Carers

2021 ◽  
pp. 1-15
Author(s):  
Eduardo Tolosa ◽  
Georg Ebersbach ◽  
Joaquim J. Ferreira ◽  
Olivier Rascol ◽  
Angelo Antonini ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Impact Assessment ◽  
Real World ◽  
European Countries ◽  
Life Questionnaire ◽  
Motor Symptoms ◽  
Non Motor Symptoms

Background: A greater understanding of the everyday experiences of people with Parkinson’s disease (PD) and their carers may help improve clinical practice. Objective: The Parkinson’s Real-world Impact assesSMent (PRISM) study evaluated medication use, health-related quality of life (HRQoL) and the use of healthcare resources by people with PD and their carers. Methods: PRISM is an observational cross-sectional study, in which people with PD and their carers completed an online survey using structured questionnaires, including the Parkinson’s Disease Quality of Life Questionnaire (PDQ-39), Non-Motor Symptoms Questionnaire (NMSQuest) and Zarit Burden Interview (ZBI). Results: Data were collected from 861 people with PD (mean age, 65.0 years; mean disease duration, 7.7 years) and 256 carers from six European countries. People with PD reported a large number of different co-morbidities, non-motor symptoms (mean NMSQuest score, 12.8), and impaired HRQoL (median PDQ-39 summary score, 29.1). Forty-five percent of people with PD reported at least one impulse control behaviour. Treatment patterns varied considerably between different European countries. Levodopa was taken in the last 12 months by 85.9% of participants, and as monotherapy by 21.8% . Carers, who were mostly female (64.8%) and the partner/spouse of the person with PD (82.1%), reported mild to moderate burden (mean ZBI total score, 26.6). Conclusions: The PRISM study sheds light on the lives of people with PD and those who care for them, re-emphasising the many challenges they face in everyday life. The study also provides insights into the current treatment of PD in Europe.

1.032 NON-MOTOR SYMPTOMS AND QUALITY OF LIFE IN PATIENTS WITH PARKINSON'S DISEASE

2012 ◽  
Vol 18 ◽  
pp. S18
Author(s):  
D. Joshi ◽  
P. Chatterjee ◽  
B. Kumar ◽  
A.Z. Ansari ◽  
V.N. Mishra ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Symptoms ◽  
Non Motor Symptoms

scholarly journals Short-term quality of life after subthalamic stimulation depends on non-motor symptoms in Parkinson's disease

2018 ◽  
Vol 11 (4) ◽  
pp. 867-874 ◽  
Author(s):  
Haidar Salimi Dafsari ◽  
Luisa Weiß ◽  
Monty Silverdale ◽  
Alexandra Rizos ◽  
Prashanth Reddy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Symptoms ◽  
Short Term ◽  
Subthalamic Stimulation ◽  
Non Motor Symptoms

scholarly journals Non-Motor Symptoms of Essential Tremor Are Independent of Tremor Severity and Have an Impact on Quality of Life

2016 ◽  
Vol 6 (0) ◽  
pp. 361 ◽  
Author(s):  
Thomas Musacchio ◽  
Veronika Purrer ◽  
Aikaterini Papagianni ◽  
Anna Fleischer ◽  
Daniel Mackenrodt ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Essential Tremor ◽  
Motor Symptoms ◽  
Non Motor Symptoms

Frequency of non‐motor symptoms and their impact on the quality of life in patients with Parkinson's disease: a prospective descriptive case series

2019 ◽  
Vol 20 (2) ◽  
pp. 206-211 ◽  
Author(s):  
Aydin Gulunay ◽  
Gul Y. Cakmakli ◽  
Mehmet I. Yon ◽  
Ersin K. Ulusoy ◽  
Mehmet Karakoc
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Case Series ◽  
Motor Symptoms ◽  
Non Motor Symptoms
Sign in / Sign up

Export Citation Format

Share Document