scholarly journals Human sperm DNA damage has an effect on immunological interaction between spermatozoa and fallopian tube

Andrology ◽  
2019 ◽  
Vol 7 (2) ◽  
pp. 228-234 ◽  
Author(s):  
Z. Zandieh ◽  
M. Ashrafi ◽  
K. Aflatoonian ◽  
R. Aflatoonian
Keyword(s):  
Dna Damage ◽  
Fallopian Tube ◽  
Human Sperm ◽  
Sperm Dna Damage ◽  
Sperm Dna

Dynamic assessment of human sperm DNA damage III: the effect of sperm freezing techniques

2020 ◽  
Author(s):  
Eva Tvrdá ◽  
Jaime Gosálvez ◽  
Francisca Arroyo ◽  
Pascual Sánchez ◽  
Ramón de Jesús Risco Delgado ◽  
...  
Keyword(s):  
Dna Damage ◽  
Dynamic Assessment ◽  
Human Sperm ◽  
Sperm Dna Damage ◽  
Sperm Dna ◽  
Sperm Freezing

miR-424/322 is downregulated in the semen of patients with severe DNA damage and may regulate sperm DNA damage

2016 ◽  
Vol 28 (10) ◽  
pp. 1598 ◽  
Author(s):  
Kai Zhao ◽  
Yaoping Chen ◽  
Ruifeng Yang ◽  
Yang Bai ◽  
Cuiling Li ◽  
...  
Keyword(s):  
Dna Damage ◽  
Human Sperm ◽  
Vital Role ◽  
Dna Integrity ◽  
Dna Double Strand Breaks ◽  
Human Seminal Plasma ◽  
Sperm Dna Damage ◽  
Sperm Dna ◽  
Murine Homologue

Sperm DNA integrity is an essential factor for accurate transmission of genetic information. Human sperm DNA damage is a common cause of male infertility but the exact mechanism remains poorly understood. Considering the vital role of microRNA (miRNA) in multiple pathophysiological processes, we hypothesised that testicular miRNA is involved in sperm DNA damage during spermatogenesis. Infertile patients with high sperm DNA fragment index (DFI; n = 94) were selected from 1090 infertile men and a total of 18 testis-specific seminal miRNAs previously identified from human seminal plasma were chosen and tested. miR-29c and miR-424 were downregulated in men with high DFI. The inhibition of these two miRNAs in mice confirmed the role of miR-424 (murine homologue miR-322) in sperm DNA damage during spermatogenesis; by contrast, miR-29c exhibited a negative result. Thus, miR-424/322 is involved in sperm DNA damage. Furthermore, the dysregulation of this miRNA can induce DNA double-strand breaks during spermatogenesis.

scholarly journals Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis

2009 ◽  
Vol 24 (9) ◽  
pp. 2061-2070 ◽  
Author(s):  
L.K. Thomson ◽  
S.D. Fleming ◽  
R.J. Aitken ◽  
G.N. De Iuliis ◽  
J.-A. Zieschang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Human Sperm ◽  
Sperm Dna Damage ◽  
Sperm Dna

scholarly journals Human sperm sex chromosome disomy and sperm DNA damage assessed by the neutral comet assay

2014 ◽  
Vol 29 (10) ◽  
pp. 2148-2155 ◽  
Author(s):  
M. E. McAuliffe ◽  
P. L. Williams ◽  
S. A. Korrick ◽  
R. Dadd ◽  
F. Marchetti ◽  
...  
Keyword(s):  
Dna Damage ◽  
Comet Assay ◽  
Sex Chromosome ◽  
Human Sperm ◽  
Sperm Dna Damage ◽  
Neutral Comet Assay ◽  
Sperm Dna

scholarly journals The effect of two cryopreservation methods on human sperm DNA damage

Cryobiology ◽  
2016 ◽  
Vol 72 (3) ◽  
pp. 210-215 ◽  
Author(s):  
Taixiu Liu ◽  
Jianfang Gao ◽  
Niya Zhou ◽  
Min Mo ◽  
Xiaogang Wang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Human Sperm ◽  
Sperm Dna Damage ◽  
Sperm Dna

scholarly journals Dynamic assessment of human sperm DNA damage II: the effect of sperm concentration adjustment during processing

2019 ◽  
Vol 36 (4) ◽  
pp. 799-807 ◽  
Author(s):  
Eva Tvrdá ◽  
Francisca Arroyo ◽  
Michal Ďuračka ◽  
Carmen López-Fernández ◽  
Jaime Gosálvez
Keyword(s):  
Dna Damage ◽  
Dynamic Assessment ◽  
Sperm Concentration ◽  
Human Sperm ◽  
Sperm Dna Damage ◽  
Sperm Dna

scholarly journals Human sperm DNA damage inhibition and antioxidant activity of T. arjuna bark: an in vitro study

3 Biotech ◽  
2017 ◽  
Vol 7 (3) ◽  
Author(s):  
Parameswari R ◽  
Kamini A. Rao ◽  
K. Mano ◽  
M. Aruna ◽  
AS Vickram ◽  
...  
Keyword(s):  
Dna Damage ◽  
Antioxidant Activity ◽  
In Vitro Study ◽  
Human Sperm ◽  
Vitro Study ◽  
Sperm Dna Damage ◽  
Sperm Dna
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