scholarly journals Sperm morphology: assessment, pathophysiology, clinical relevance, and state of the art in 2017

Andrology ◽  
2017 ◽  
Vol 5 (5) ◽  
pp. 845-862 ◽  
Author(s):  
N. Gatimel ◽  
J. Moreau ◽  
J. Parinaud ◽  
R. D. Léandri
Keyword(s):  
Clinical Relevance ◽  
Sperm Morphology ◽  
State Of The Art ◽  
Sperm Morphology Assessment

scholarly journals Our experience in sperm morphology assessment

2010 ◽  
Vol 13 (2) ◽  
pp. 201-202 ◽  
Author(s):  
Julia Irene Ariagno ◽  
Susana Mercedes Curi ◽  
Patricia Chenlo ◽  
Herberto Ernesto Hector Repetto ◽  
Mercedes Norma Pugliese ◽  
...  
Keyword(s):  
Sperm Morphology ◽  
Sperm Morphology Assessment

scholarly journals Clinical Relevance of State-of-the-Art Analysis of Surface Electromyography in Cerebral Palsy

2020 ◽  
Vol 11 ◽  
Author(s):  
Germana Cappellini ◽  
Francesca Sylos-Labini ◽  
Carla Assenza ◽  
Laura Libernini ◽  
Daniela Morelli ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Neurological Disorders ◽  
Surface Electromyography ◽  
Clinical Relevance ◽  
State Of The Art ◽  
Neuromuscular System ◽  
Neural Controllers ◽  
Children With Cerebral Palsy ◽  
Tendon Surgery ◽  
Reference Databases

Surface electromyography (sEMG) can be used to assess the integrity of the neuromuscular system and its impairment in neurological disorders. Here we will consider several issues related to the current clinical applications, difficulties and limited usage of sEMG for the assessment and rehabilitation of children with cerebral palsy. The uniqueness of this methodology is that it can determine hyperactivity or inactivity of selected muscles, which cannot be assessed by other methods. In addition, it can assist for intervention or muscle/tendon surgery acts, and it can evaluate integrated functioning of the nervous system based on multi-muscle sEMG recordings and assess motor pool activation. The latter aspect is especially important for understanding impairments of the mechanisms of neural controllers rather than malfunction of individual muscles. Although sEMG study is an important tool in both clinical research and neurorehabilitation, the results of a survey on the clinical relevance of sEMG in a typical department of pediatric rehabilitation highlighted its limited clinical usage. We believe that this is due to limited knowledge of the sEMG and its neuromuscular underpinnings by many physiotherapists, as a result of lack of emphasis on this important methodology in the courses taught in physical therapy schools. The lack of reference databases or benchmarking software for sEMG analysis may also contribute to the limited clinical usage. Despite the existence of educational and technical barriers to a widespread use of, sEMG does provide important tools for planning and assessment of rehabilitation treatments for children with cerebral palsy.

Pasireotide in the treatment of neuroendocrine tumors: a review of the literature

2018 ◽  
Vol 25 (6) ◽  
pp. R351-R364 ◽  
Author(s):  
Giovanni Vitale ◽  
Alessandra Dicitore ◽  
Concetta Sciammarella ◽  
Sergio Di Molfetta ◽  
Manila Rubino ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Clinical Relevance ◽  
State Of The Art ◽  
Somatostatin Receptor ◽  
Somatostatin Analogs ◽  
Future Perspectives ◽  
Review Of The Literature ◽  
Antiproliferative Effects ◽  
High Affinity ◽  
Well Differentiated

Somatostatin analogs have an important role in the medical therapy of neuroendocrine tumors (NETs). Octreotide and lanreotide, both somatostatin analogs binding with high affinity for the somatostatin receptor (SSTR)2, can control symptoms in functional NETs. In addition, these compounds, because of their antiproliferative effects, can stabilize growth of well-differentiated NETs. Pasireotide is a novel multireceptor-targeted somatostatin analog with high affinity for SSTR1, 2, 3, and 5. This review provides an overview of the state of the art of pasireotide in the treatment of NETs, with the aim of addressing clinical relevance and future perspectives for this molecule in the management of NETs.

Status of sperm morphology assessment: an evaluation of methodology and clinical value

2015 ◽  
Vol 103 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Leonie van den Hoven ◽  
Jan C.M. Hendriks ◽  
Jozé G.M. Verbeet ◽  
Johan R. Westphal ◽  
Alex M.M. Wetzels
Keyword(s):  
Sperm Morphology ◽  
Clinical Value ◽  
Sperm Morphology Assessment

scholarly journals Familial Mediterranean fever: clinical state of the art

QJM ◽  
2020 ◽  
Author(s):  
B H Egeli ◽  
S Ugurlu
Keyword(s):  
Familial Mediterranean Fever ◽  
Clinical Relevance ◽  
Scientific Literature ◽  
State Of The Art ◽  
Treatment Modalities ◽  
Clinical State ◽  
Inflammation Research ◽  
The Past ◽  
Mediterranean Fever

Summary As the inflammation research improves year-by-year, so does our understanding of the autoinflammatory conditions. Over the past years, the number of monogenic autoinflammatory conditions snowballed thanks to our understanding of basic immunology and genetics. Familial Mediterranean fever (FMF), being the entrance to this fascinating world, still has clinical relevance as it enables us to understand our approach to these patients, treatment modalities and pathological mechanisms. This review can be used as a tool for clinicians already working with FMF patients to update themselves on recent scientific literature.

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